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arGEN-X Identifies Potent Antibody Antagonists against Complex Chronic Pain Target Nav1.7
Date:9/12/2013

#8482; has exceeded all our expectations. Once again, our technology platform has enabled us to generate novel antibody leads against a complex and high value target, confirming its huge potential in the dynamic therapeutic antibody space. We are eager to broaden this campaign in partnership now and progress our most promising leads into development."

Professor de Haard will present the Nav1.7 program for the first time in public forum in an arGEN-X-sponsored platform presentation at the 11th Annual 'Discovery on Target' conference, Boston, MA, USA (September 24-26, 2013). The presentation will showcase the attributes of SIMPLE Antibody™ in addressing the most challenging, high value targets in disease.

About arGEN-X - http://www.arGEN-X.com

arGEN-X is a clinical stage human therapeutic antibody company that is rapidly developing a product pipeline using its unique suite of antibody technologies. arGEN-X is creating first and best in class antibody therapeutics with highly differentiated target product profiles. Its therapeutic antibody programs, focused on cancer and autoimmune indications, are designed to deliver tangible benefits to patients with these diseases.

arGEN-X's SIMPLE Antibody™ platform generates an unprecedented diversity of high quality human antibodies, enabling optimal product choice. SIMPLE Antibodies™ are able to address and modulate any disease target, including complex receptors such as GPCRs and ion channels and highly conserved targets that are often intractable with other antibody technologies. SIMPLE Antibody™ generated leads are further differentiated as products through enhancement of cell killing properties (POTELLIGENT®, licensed from BioWa Inc.) and optimization of circulation time and distribution in the body (NHance™). arGEN-X is also developing ABDEG™ technology, to pote
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