Navigation Links
Analysis of Caliper's Phase I EPA ToxCast™ Data Published in Leading Scientific Journal
Date:2/24/2011

HOPKINTON, Mass., Feb. 24, 2011 /PRNewswire/ -- Caliper Life Sciences, Inc. (Nasdaq: CALP), today announced that the results of its initial screening efforts under the U.S. Environmental Protection Agency's (EPA) ToxCast program have been published in the scientific journal Toxicology. Key findings reported include (1) a high level of quality and reproducibility in the dataset allowing for robust statistical analyses, and (2) the role that specific targets in biological pathways could play in toxicity events. These findings underscore the success of the Phase I ToxCast effort and support continued expansion of the program to build predictive models for identifying chemicals with high risk for human toxicity or environmental hazard.  Caliper has recently been awarded three new task orders with an aggregate value of $3.1 million to fund additional activities under the EPA ToxCast program.  

The initial goal of the ToxCast program is to create a database of in vitro (laboratory) assay data on a broad set of compounds for which in vivo (animal) safety data already exists. The Toxicology article covers the first phase of ToxCast data produced by Caliper, which involved more than 93,000 chemical-assay pairs. Caliper has contributed 292 assays, more than half of all of the assays, to the EPA ToxCast program. The long term goal of this program is to identify in vitro assays that can predict toxicity in humans and animals and then employ those predictive tests to supplement or replace existing animal-based tests, thus reducing the cost and improving the speed of regulatory approval of new environmental chemicals.    

The article published in Toxicology (Volume 282, Nos. 1-2, pp. 1-15) is entitled "Activity profiles of 309 ToxCast chemicals evaluated across 292 biochemical targets".  The authors include senior scientific staff from
'/>"/>

SOURCE Caliper Life Sciences, Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Anthera Announces Conference Call to Discuss Analytical Method and Timing of Upcoming VISTA-16 Biomarker Analysis
2. Reportlinker Adds U.S. Pain Management Products & Services: a Market Analysis - 7th Edition
3. Reportlinker Adds Generic and innovative drug market in CE countries 2011 - Comparative analysis, reimbursement policies and development forecasts for 2011-2013
4. Reportlinker Adds Brand Erosion Post-Patent Expiry - An analysis of small molecule brand erosion post-patent expiry
5. Reportlinker Adds Dental Implants and Biomaterials - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016
6. Reportlinker Adds Cardiac Rhythm Management (CRM) Devices - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016
7. Reportlinker Adds Glucose Monitoring Systems - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016
8. Reportlinker Adds Magnetic Resonance Imaging (MRI) Systems - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016
9. Reportlinker Adds AstraZeneca PLC Market Share Analysis
10. New Sub-Analysis of RE-LY Trial Examines Pradaxa in Patients with Atrial Fibrillation Undergoing Cardioversion
11. New Software for Improving the Analysis of OCT Images
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... Amgen (NASDAQ: AMGN ) will present ... on Thursday, May 30, 2013, at the Westin Boston Waterfront ... Eastern Daylight Time. Arvind Sood , vice ... conference. Live audio of the presentation can be accessed from ... Investors. A replay of the webcast will also be available ...
(Date:5/23/2013)... Hearing health affects a man,s lifestyle, and if he wants ... engaged, he should address any hearing loss he may be ... Hearing Institute (BHI) is delivering to men around the ... which leads up to and includes Father,s Day. This year, ... 16. To help men address their hearing ...
(Date:5/23/2013)... , May 23, 2013  TeamHealth Medical ... nurse triage and nurse advice lines, announces its ... comprising physician, nursing and administrative leaders, provides clinical ... quality and cost-effective services for hospital clients, physician ... national healthcare system evolves, it,s imperative to continuously ...
Breaking Medicine Technology:Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4TeamHealth Medical Call Center Forms Clinical Advisory Committee 2
... EDDA Technology, a leading provider of advanced computer ... successful commercial installation of its IQQA®-Liver Enterprise product ... one of the top performing living donor liver ... use EDDA Technology,s IQQA®-Liver Enterprise in conjunction with ...
... Perrigo Company (Nasdaq: PRGO ; TASE) ... Papa will present at the 29th Annual J.P. Morgan ... (PST) at the Westin St. Francis Hotel in San ... following link: http://jpmorgan.metameetings.com/webcasts/healthcare11/directlink?ticker=PRGO Perrigo Company ...
Cached Medicine Technology:EDDA Technology Successfully Installs IQQA®-Liver at Mayo Clinic in Arizona 2
(Date:5/24/2013)... Florida (PRWEB) May 24, 2013 KC and ... the Title Sponsors for FreeRide836. Their oldest sons, Kyle and ... and Tracey Russell family and several professional kiteboarders. , KC ... amazing project. "This has miraculously come together such that virtually ... able to participate." , 20 kite boarders will meet at ...
(Date:5/24/2013)... May 24, 2013 CHI-California Healthcare ... and the California congressional delegation, joined by over ... industry user fees paid to the U.S. Food ... that future across-the-board cuts will not include user ... FY14 Agriculture, Rural Development and FDA Appropriations Bill. ...
(Date:5/24/2013)... failed to replicate what appeared to be breakthrough results ... were published last year in the journal Science ... suggested that the drug bexarotene (marketed as Targretin) could ... a pathological hallmark of Alzheimer,s disease in ... the 2012 report, drug treatment quickly removed most of ...
(Date:5/24/2013)... to the development of infantile myofibromatosis (IM)a disorder characterized ... tissuemay provide new therapeutic targets, according to researchers from ... findings, published in the American Journal of Human ... this debilitating disease, for which the only current treatment ... IM is an inheritied disorder that develops in infancy ...
(Date:5/24/2013)... (HealthDay News) -- Low-income, minority parents have more ... are more open to vaccinating their daughters against ... new study contends. Conversely, white, middle-class parents ... their daughters, according to researchers from the Boston ... will get an HPV-related cancer each year, many ...
Breaking Medicine News(10 mins):Health News:FreeRide836 Sponsor Living Fuel, The Leader in Superfood Nutrition, Announces Kiteboard Launch For This Sunday To Raise Money For Orphans In Africa 2Health News:FreeRide836 Sponsor Living Fuel, The Leader in Superfood Nutrition, Announces Kiteboard Launch For This Sunday To Raise Money For Orphans In Africa 3Health News:California Biomedical Industry Leaders Urge Congress to Take Action on FDA User Fees for FY2014 2Health News:California Biomedical Industry Leaders Urge Congress to Take Action on FDA User Fees for FY2014 3Health News:Multiple research teams unable to confirm high-profile Alzheimer's study 2Health News:Multiple research teams unable to confirm high-profile Alzheimer's study 3Health News:Researchers identify first drug targets in childhood genetic tumor disorder 2Health News:Low-Income, Minority Parents More Open to HPV Vaccine for Girls, Study Says 2
... hockey player Hayley Wickenheiser one of only two women ... Mannatech,(Nasdaq: MTEX ) athlete Hayley Wickenheiser has been ... world., http://sportsillustrated.cnn.com/2008/extramustard/03/28/25.toughest.at ,hletes/, Wickenheiser is one ... list, which,was published on the Sports Illustrated Web site ...
... with Murray,s Chicken,s Green and Sustainable, Commitment ... Water(TM), ATLANTA, April 16 In keeping ... most natural,chicken possible, Murray,s Chicken, a family-run poultry ... to electrolyzed water as its primary,processing cleaning agent. ...
... 15 The Medical Tourism,Association, the international non-profit ... announces the World Medical Tourism &,Global Health Congress, ... tourism convention to take place in the United ... at the Westin St.,Francis in San Francisco, California, ...
... cone snail venom and African plants are being used by ... to treat chronic pain. , Professor David Craik and ... received $218,275 from the National Health and Medical Research Council ... available for Australians to use. , Studies on the ...
... China, April 16 /Xinhua-PRNewswire-FirstCall/ -- China Sky ... ,the Company,) (OTC Bulletin,Board: CSKI), a leading ... external use in the People,s Republic,of China ... participation in the 20th International Medical Instruments ...
... and human ... resources, ... peak performance within Health Information Management (HIM),departments, today announced the appointment ... Precyse from Pegasus,Communications where she served as Senior Vice President of ...
Cached Medicine News:Health News:Sports Illustrated Names Team Mannatech Athlete to Top 25 Tough List 2Health News:Sports Illustrated Names Team Mannatech Athlete to Top 25 Tough List 3Health News:Electrolyzed Water Gives Boost to Eliminating Food-Borne Bacteria Such as Salmonella, E. coli and Listeria Murray's Chicken to be First Poultry Processor to Utilize New Technology in its Food Sanitation Process 2Health News:Electrolyzed Water Gives Boost to Eliminating Food-Borne Bacteria Such as Salmonella, E. coli and Listeria Murray's Chicken to be First Poultry Processor to Utilize New Technology in its Food Sanitation Process 3Health News:Electrolyzed Water Gives Boost to Eliminating Food-Borne Bacteria Such as Salmonella, E. coli and Listeria Murray's Chicken to be First Poultry Processor to Utilize New Technology in its Food Sanitation Process 4Health News:Medical Tourism Association Announces World's Largest Medical Tourism Convention in San Francisco, CA USA - September 9-12, 2008 2Health News:Medical Tourism Association Announces World's Largest Medical Tourism Convention in San Francisco, CA USA - September 9-12, 2008 3Health News:Cone snails and plants used to develop oral drug for pain 2Health News:China Sky One Medical, Inc. Announces Its Successful Participation in the 20th International Medical Instruments and Equipment Exhibition 2Health News:China Sky One Medical, Inc. Announces Its Successful Participation in the 20th International Medical Instruments and Equipment Exhibition 3Health News:Precyse Solutions Appoints Karen Heisler as New Corporate Vice President, Human Resources 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: