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aTyr Pharma Completes $49 Million Financing to Advance a Therapeutic Pipeline for Rare Autoimmune Diseases from a Newly Discovered Class of Proteins, Physiocrines
Date:7/29/2013

SAN DIEGO, July 29, 2013 /PRNewswire/ -- aTyr Pharma, an innovative protein therapeutics enterprise focused on rare diseases, announced today the successful completion of a $49 million financing. A premier, global public investment fund joined existing investors Alta Partners, Cardinal Partners, Domain Associates and Polaris Partners in the equity financing. The financing supports the clinical development of aTyr's first therapeutic program to treat rare autoimmune diseases and a rare disease pipeline in immune disorders.  The financing had robust demand, and the private stock placement was capped at $49 million by the company. 

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"Our focus on new biology in immunology rapidly translated into development of protein therapeutics to treat essentially untreatable, grave immune disorders.  Our existing and new investors recognized the promise in a new class of proteins, Physiocrines, to treat many different types of disease with proteins made by the human body to orchestrate our immune system," said John Mendlein, Ph.D., CEO and executive chairman of aTyr Pharma. "Our emerging pipeline in immunomodulation represents an industry unique opportunity to therapeutically intervene via the basic mechanisms of innate and adaptive immunity in a way never enabled before. The aTyr team believes these mechanisms will benefit patients with grave outcomes in ways that antibody and small molecule approaches can not because Physiocrines evolved to naturally balance the immune system to resolve inflammation rather than being a designed inhibitor of pro-inflammatory pathways."

About Physiocrines

Physiocrines act as extracellular signaling molecules to orchestrate cellular homeostasis in response to stress. Physiocrines are naturally occurring proteins derived
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SOURCE aTyr Pharma
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