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aTyr Pharma Closes $10 Million Venture Debt Loan from Silicon Valley Bank
Date:7/29/2013

SAN DIEGO, July 29, 2013 /PRNewswire/ -- aTyr Pharma, an innovative protein therapeutics enterprise focused on rare diseases, announced today the close of $10 million debt financing from Silicon Valley Bank to support the clinical development of aTyr's first therapeutic program to treat rare autoimmune diseases and a rare disease pipeline in immune disorders.

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"In conjunction with our Series D financing, this loan provides additional funding as we translate Physiocrine biology into a new class of protein therapeutics to treat many different types of immune disorders," said John Mendlein, Ph.D., CEO and executive chairman of aTyr Pharma. 

"We're proud to be a partner of aTyr Pharma, offering the added flexibility the company needs to pursue its meaningful goals," said Mike White, managing director in life sciences for Silicon Valley Bank in San Diego. "Working with life sciences companies like aTyr, which are in pursuit of innovations that will directly impact the quality of people's lives, is inspiring and rewarding."

About Physiocrines

Physiocrines act as extracellular signaling molecules to orchestrate cellular homeostasis in response to stress.  Physiocrines are naturally occurring proteins derived from tRNA synthetases that play fundamental roles in the function of human physiology and the resolution of inflammation. As potent endogenous modulators of inflammation, Physiocrines offer the opportunity for modulating biological pathways through new naturally occurring mechanisms, many of which have multiple therapeutic advantages, including improved selectivity, efficacy and reduced side effect profiles compared to many existing anti-inflammatory therapeutics.

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