Navigation Links
Zusetzen von Obinutuzumab (GA101) oder Rituximab zu Chlorambucil verbessert Aussichten für ältere Patienten mit chronischer lymphatischer Leukämie (CLL) und gleichzeitig vorliegenden Erkrankungen (Komorbiditäten)
Date:6/14/2013

STOCKHOLM, June 14, 2013 /PRNewswire/ --

Dr. Valentin Goede wird auf dem 18. Kongress der European Hematology Association in Stockholm vielversprechende Ergebnisse für ältere CLL-Patienten vorstellen.

CLL ist die häufigste Leukämieform in der westlichen Welt. Viele CLL-Patienten sind Senioren mit Komorbiditäten, so dass die aggressiven Standardbehandlungen für sie nicht in Frage kommen. Bislang war ungeklärt, ob (i) eine Kombinationsbehandlung mit dem Chemotherapeutikum Chlorambucil plus einem monoklonalen CD20-Antikörper die Aussichten für diese Patienten gegenüber einer Behandlung mit Chlorambucil allein verbessert und ob (ii) diese Patienten mehr vom Einsatz des neuartigen CD20-Antikörpers Obinutuzumab (GA101) im Vergleich zum zugelassenen CD20-Antikörper Rituximab profitieren.

Die von der Deutschen CLL-Studiengruppe (DCLLSG) in Zusammenarbeit mit Hoffmann-La Roche durchgeführte CLL11-Studie vergleicht erstmals direkt die folgenden Behandlungen für ältere Patienten mit Komorbiditäten: GA101 plus Chlorambucil, Rituximab plus Chlorambucil und Chlorambucil allein.

Das Zusetzen von GA101 oder Rituximab zu Chlorambucil verlängerte die Zeit, in der die Menschen ohne Verschlechterung ihres Zustands lebten (progressionsfreies Überleben), gegenüber Chlorambucil allein wesentlich. Beide Kombinationsbehandlungen zeigten ein akzeptables Sicherheitsprofil für die untersuchte Patientengruppe. Diese Ergebnisse sind ein bedeutender Schritt hin zur Verbesserung der Behandlung älterer CLL-Patienten mit Komorbiditäten (obwohl die Ergebnisse des Direktvergleichs der zwei Antikörper erst zu einem späteren Zeitpunkt der Studie verfügbar sein werden).

Präsentator : Valentin Goede

Zugehörigkeit: Deutsc
'/>"/>

SOURCE European Hematology Association
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Rituximab Promotes Long-Term Response for Patients with Immune Destruction of Platelets
2. Neue klinische Richtlinien für ältere Patienten mit Typ 2 Diabetes, um einen europaweiten Pflegenotstand zu verhindern
3. Een studie in het New England Journal of Medicine bevestigt dat universele dekolonisatie van ic-patiënten voor 44% minder bloedstroominfecties zorgt
4. Studie von Grifols zeigt, dass eine höhere Dosis von PROLASTIN-C den Alpha1-PI-Spiegel in Patienten mit AAT-Mangel in den normalen Bereich anhebt
5. American College of Chest Physicians (ACCP) und Simbionix arbeiten zusammen, um klinische Ausbildung und Patientensicherheit zu verbessern
6. Wie die Operation am echten Patienten - Simulationsausbildung für Gefäßchirurgen und Kardiologen
7. Krebspatienten an neuem Schweizer Zentrum für Strahlentherapie werden mit Elektas fortschrittlichem Versa HD-System behandelt
8. IDEV gibt Ergebnisse von Studie zur Revaskularisation mit Supera an echten Patienten (RESTORE) bekannt - Studie demonstriert positive klinische Ergebnisse bei schwerkranken Patienten mit langen Läsionen
9. Neue europaweite Umfrage Ergibt, dass die Behandlung chronischer Schmerzen bei vielen Patienten unzureichend ist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... , July 29, 2014 Numotion,s Board of Directors ... Swinford will be the company,s new Chief Executive Officer. ... 22-year career at GE where he worked primarily for GE ... revenue to over $5 billion. His most recent position was ... "I am thrilled to join Numotion," said ...
(Date:7/29/2014)... NEW YORK , July 29, 2014 ... and services for the science, technical, and medical communities, ... , the first off-line mobile application of the world-renowned ... of the new AccessMedicine App , available for ... users will now be able to gain access to ...
(Date:7/29/2014)... 29, 2014  Neurocrine Biosciences, Inc. (Nasdaq: ... its second quarter 2014 financial results after the Nasdaq ... then host a live conference call and webcast to ... Thursday morning, August 7, 2014 at 8:00 a.m. Eastern ... access the live conference call by dialing 866-952-1907 (US) ...
Breaking Medicine Technology:Numotion Names Mike Swinford CEO 2McGraw-Hill Education Professional's AccessMedicine App Delivers Instant Access to Essential Diagnostic Tools 2McGraw-Hill Education Professional's AccessMedicine App Delivers Instant Access to Essential Diagnostic Tools 3Neurocrine Biosciences Announces Conference Call And Webcast To Report Second Quarter 2014 Financial Results 2
... BILLERICA, Mass., May 7, 2011 Objet Geometries Ltd. ... rapid prototyping and additive manufacturing, will demonstrate the ... LAB DAY West. Exhibiting at Booth B6, B-7, Objet will ... throughout the show on the Objet Eden260V™ 3D printing system. ...
... PRINCETON, N.J., May 6, 2011 Covance Inc. (NYSE: ... Baird,s 2011 Growth Stock Conference on Tuesday, May 10, 2011 ... of the presentation at www.covance.com .  In order to ... minutes early. Covance, with headquarters in Princeton, New ...
Cached Medicine Technology:Objet to Showcase Exceptionally Detailed and Accurate Dental Models at LMT LAB DAY West 2Objet to Showcase Exceptionally Detailed and Accurate Dental Models at LMT LAB DAY West 3Objet to Showcase Exceptionally Detailed and Accurate Dental Models at LMT LAB DAY West 4Covance to Present at Baird's 2011 Growth Stock Conference 2
(Date:7/30/2014)... Pain Free Living web: Superior ... pain relief and improved performance. This new magnetic sports ... a silicone core that is sheathed in nylon soaked ... embedded with scalar energy and Schumann frequency thus making ... has 12 years experience developing magnetic bracelets. We developed ...
(Date:7/30/2014)... Nuanced Media, a specialist in web design ... the Medical Web Design Trends of 2014. The web ... multiple agencies and the medical web design industry throughout the ... the industry grows. Therefore it is important for existing practices ... enjoy most. New trends are defined by advances in the ...
(Date:7/29/2014)... Paul Mata, CEO of ‘Create Indestructible Wealth,’ ... 30 Days” E-book. The e-book includes a myriad of fast ... cash. Examples include downloading and utilizing specific phone apps ... people monetize the assets they didn't know they had like ... find in their garage. , After reading the e-book, ...
(Date:7/29/2014)... MO (PRWEB) July 30, 2014 ... have recently been awarded the Patient-Centered Medical Home ... the National Committee for Quality Assurance. Only one ... NCQA Level I, Level 2, or Level 3 ... participate in Patient-Centered Medical Home report faster access ...
(Date:7/29/2014)... 29, 2014 1Heart Caregiver Services’ ... with focus on Brain Fitness Education brings great ... Brain Fitness Program Director Tee Barr delivered an ... Care unit and the Assisted Living section of ... Enrichment Director Christy Rozsa and Aegis Life Neighborhood ...
Breaking Medicine News(10 mins):Health News:Superior Magnetics Released New Magnetic Sports Bracelet for Pain 2Health News:Nuanced Media Releases "Medical Web Design Trends of 2014" Article 2Health News:Create Indestructible Wealth Launches Innovative E-Book: “Realistic Ways to Make More Money in 30 Days” 2Health News:Saint Luke’s Medical Group Awarded Patient-Centered Medical Home 2011 Level 3 Recognition 2Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 2Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 3Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 4
... research has pointed out the increasing problem of super bugs ... ,Super bugs are a new kind of microorganisms, mainly ... wide range of antibiotics. ,The researchers of Fogarty International ... blame the use of antibiotics in agricultural farms for creating ...
... A study published in the July edition of the ... // number and severity of cases of constriction of ... ,Normally constriction of blood vessels occurs ... to strokes and neurological deficits. This can cause not ...
... In an article in the recent issue of the ... and smoking. ,Researchers have looked into the data ... a firm connection between smoking and incidence of tuberculosis ... them tested positive for tuberculin skin test. The research ...
... an important component of mammal’s daily life and more so of ... known to sleep for over 18 hours. However, it is different ... been reported in Nature that newborn bottlenose dolphins and killer whales ... moms manage with only a wink or two than the newborns. ...
... The July issue of the health journal Epidemiology has published ... of cancer are higher if there is associated infertility. ... Rockville, Maryland, and her team followed 12,193 U.S. women ... risk among infertile women with that of the general population. ...
... the womb of the mother, may have asthma at a ... an 11-year observation of incidence of asthma and other respiratory ... to incidence of asthma in childhood. Passive smoking by the ... of asthma in children. ,Researchers are of the opinion ...
Cached Medicine News:Health News:Clazosentan May help to Improve Blood Circulation after Brain Hemorrhage due to burst Aneurysm 2
... Injection is supplied in an isotonic solution ... intravenous administration. Each milliliter contains 37 megabecquerels ... calibration time, made isotonic with 9 milligrams ... benzyl alcohol. The pH is adjusted to ...
... single-detector system offers general purpose ... for gurneys and wheelchairs. This ... versatile open gantry, caudal/cephalic detector ... for SPECT and whole body ...
Stainless steel lancet blade in stainless steel....
Sharp diamond shaped double blade in stainless steel....
Medicine Products: