Navigation Links
Ziopharm Oncology's ZIO-201 - a stable formulation of palifosfamide
Date:11/25/2013

DUBLIN, November 25, 2013 /PRNewswire/ --

Research and Markets (http://www.researchandmarkets.com/research/q99tkv/ziopharm) has announced the addition of the "Ziopharm Oncology's ZIO-201 - a stable formulation of palifosfamide" report to their offering.

     (Logo: http://photos.prnewswire.com/prnh/20130307/600769)


The rationale to develop a stable formulation of palifosfamide is strong: it is the active metabolite of ifosfamide, a well-established alkylating chemotherapy agent. Palifosfamide may spare patients from the toxicities of two other inactive ifosfamide metabolites while retaining its anti-tumor activity. A phase III trial of palifosfamide in first line soft tissue sarcoma (PICASSO III) is underway with progression-free survival results expected later this year. In this report, we review the evidence supporting palifosfamide's development, the likelihood of clinical trial success, key regulatory hurdles as well as the commercial opportunity.

Key Topics Covered:

INTRODUCTION

1. Sarcomas
2. Treatment and prognosis of soft tissue sarcoma
3. Treatment of advanced or metastatic soft tissue sarcoma



PALIFOSFAMIDE

1. Palifosfamide as a single-agent
2. Palifosfamide in combination with doxorubicin
3. Phase I
4. Phase II
5. On-going phase III
6. Phase III trial in small cell lung cancer



CLINICAL AND REGULATORY OPINION

1. The rationale supporting the development of palifosfamide
2. Ifosfamide is active in STS: what does this mean for palifosfamide?
3. Phase II trial of palifosfamide suggests antitumor activity

'/>"/>

SOURCE Research and Markets
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. JDRF Announces Two Partnerships to Develop Stable, Pumpable Glucagon to Support Advanced Generation Artificial Pancreas Systems
2. EECP Therapy Receives Class lla Recommendation in European Society of Cardiology Guidelines for the Management of Stable Coronary Artery Disease
3. Hoopes Vision Surgeon First in Utah to Implant New Light Adjustable Artificial Lens
4. Soligenix Submits NIAID Contract Proposal for Development of a Thermostable Ricin Vaccine
5. European Interventional Cardiology Device Market Will Remain Stable Through 2022 at Over $1.2 Billion
6. Long Term Follow Up Data On WEB Aneurysm Embolization System Demonstrate High Rate Of Stable Occlusion In Difficult To Treat Aneurysms
7. Biodel Obtains Exclusive License to Aegis Therapeutics Technologies for Development and Commercialization of Glucagon Pharmaceutical Formulations
8. Halozymes Ultrafast Insulin Formulations Improved Postprandial Glycemic Control in Patients Living with Type 1 Diabetes: Phase 2 Study Results Presented at ADA 2012
9. Par Formulations (Formerly Edict Pharmaceuticals) Receives First ANDA Approval
10. Maximum-Strength Formulation Offers Highest Concentration and Purity
11. Biodel Awarded NIH Grant to Develop Concentrated Ultra-Rapid-Acting Insulin Formulations for Use in Artificial Pancreas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... , June 02, 2015 Research and Markets ( ... Incision Closures - Global Strategic Business Report" report to ... for the US, Canada , ... Asia-Pacific , Latin America , and ... markets for Surgical Incision Closures in US$ Million by the ...
(Date:6/2/2015)... 2, 2015  Only a quarter of physicians who ... patients they prescribe them to, according to new survey ... Medicine (BUSM) and myCME , Haymarket Medical ... Alford, M.D. , director of BUSM,s Safe and ... said, "This indicates a critical need for provider education ...
(Date:6/2/2015)... June 2, 2015  ErgoNurse, the leader in bedside safety ... products in the United States , have ... long-term care and skilled nursing markets. ... Thousands of ... fully take advantage of the ErgoNurse products to stop unnecessarily ...
Breaking Medicine Technology:Surgical Incision Closures - Global Strategic Business Report 2015 2Survey Results Show Few Doctors Are Very Confident Managing Patients on Opioids 2ErgoNurse and Briggs Healthcare Positioned to Completely Eliminate the Unnecessary Cost of Healthcare-Related Back Injuries 2
... July 22, and OSAKA, Japan, July 23 ... Takeda Global Research & Development Center, Inc., a wholly ... U.S. Food and Drug Administration (FDA) that the FDA ... for the fixed-dose combination (FDC) of alogliptin and ACTOS((R)) ...
... , MENLO PARK, Calif., July 22 Apieron, ... positive coverage policy for the measurement of exhaled nitric oxide ... peer-reviewed evidence is sufficient to support benefit coverage for the ... the measurement of exhaled nitric oxide is considered medically necessary ...
Cached Medicine Technology:Takeda Provides Update on the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl) 2Takeda Provides Update on the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl) 3CareFirst BCBS Covers eNO Measurement for Diagnosis, Asthma Treatment 2
(Date:6/2/2015)... NC (PRWEB) June 02, 2015 Food ... hosting its sixth annual “Thriller on the Griller” events, ... Carolina and South Carolina locations. Each event will raise ... dedicated to restoring a sense of self, restoring the ... and our military families. , Through these events, ...
(Date:6/2/2015)... June 02, 2015 Highly qualified dental care ... plan to drive prolific change in the dental tourism industry ... Team Dental Clinic offers a full range of superior ... structure for dental tourism. , Partnered with a top ... committed to advancing dentistry and has earned a reputation as ...
(Date:6/2/2015)... The term “Augmented Reality” was coined in ... the real world. Since then many promising technologies have ... map of the vasculature on the surface of the ... AccuVein, the leader in vein visualization, exemplifies this growth ... such widespread adoption of its AccuVein AV400 devices that ...
(Date:6/2/2015)... “ Radaris ” was featured on NewsWatch as ... the latest and coolest applications on the market for iOS, ... technology expert, conducted the app review and shared with viewers ... a person. , According to Psychology Today, humans are a ... explain that curiosity is a part of human development. People ...
(Date:6/2/2015)... FL (PRWEB) June 02, 2015 MedPro ... staffing services to healthcare facilities, today announced the worldwide ... and effective mobile tool to help candidates find best ... Glassdoor survey released in 2014, 9 in 10 job ... during their job search. , The MedPro Top Jobs ...
Breaking Medicine News(10 mins):Health News:Food Lion to Launch “Thriller on the Griller” Events to Benefit Military Families through Hope For The Warriors® 2Health News:Food Lion to Launch “Thriller on the Griller” Events to Benefit Military Families through Hope For The Warriors® 3Health News:Team Dental Clinic Unveils Plan to Drive Change in the Dental Tourism Industry 2Health News:Team Dental Clinic Unveils Plan to Drive Change in the Dental Tourism Industry 3Health News:Vein Visualization Emerges as Premier Augmented Reality Application 2Health News:A Comprehensive People Search Application Was Featured on NewsWatch Television 2Health News:MedPro Healthcare Staffing Launches New MedPro Top Jobs App To Facilitate Job Search For Healthcare Professionals 2
... French study in rats finds olanzapine changes metabolism in ... of the antipsychotic medication olanzapine may put a person ... 2 diabetes, new findings show. , A team of ... found that, after consuming olanzapine over several weeks, the ...
... the Country Gather to Discuss, Interactive Patient Care Topics and ... ... Patient Experience, WASHINGTON, April 7, 2008 ... today,announced the kick-off of GetConnected2008. Designed exclusively for the,GetWellNetwork community, ...
... Advanced Life Sciences,Holdings, Inc. (Nasdaq: ADLS ), ... live webcast at 8:30 am (EDT) on Thursday, April ... discuss the Company,s April 7, 2008,meeting with The US ... for the Company,s novel once-a-day oral antibiotic, cethromycin,as a ...
... is caused by mutations that allow defective blood ... effective therapies it is crucial to know which mutations ... leukaemic cells. Researchers from the European Molecular Biology Laboratory ... the Universities of Harvard, USA, and Lund, Sweden, have ...
... N.Y., April 7, 2008 CardWorks Servicing, LLC,("CardWorks") ... known as Cardholder Management Services, LLC ("CMS"), announced,today ... the new HumanaAdvance,Visa Card. CardWorks will partner with ... offer the HumanaAdvance Visa. Humana,is one of the ...
... treatment aren,t known, researchers say , , MONDAY, April 7 ... bone density and reduce bone loss in older men ... prevent osteoporosis, a new study suggests. , Testosterone ... muscle mass in some men. However, the hormone treatment ...
Cached Medicine News:Health News:Antipsychotic Drug Boosts Risk of Heart Disease, Diabetes 2Health News:GetWellNetwork Kicks Off GetConnected2008, First Annual Users Conference 2Health News:GetWellNetwork Kicks Off GetConnected2008, First Annual Users Conference 3Health News:Advanced Life Sciences to Host Conference Call to Discuss April 7th Meeting with FDA 2Health News:Advanced Life Sciences to Host Conference Call to Discuss April 7th Meeting with FDA 3Health News:An unexpected way to cause leukemia 2Health News:CardWorks Named Servicer of Choice for Innovative Credit Card for Healthcare Services 2Health News:CardWorks Named Servicer of Choice for Innovative Credit Card for Healthcare Services 3Health News:Testosterone Therapy May Reduce Bone Loss in Older Men 2
... new Finnpipette Focus from Thermo ... combine ergonomics with uncompromising performance. ... plate offers a custom fit ... new shorter tip cones allow ...
... Reference Series 2000 Pipette is a synonym ... compact and robust design, and superior operating ... to operate the measuring stroke and blow-out ... features:Eppendorf "pipette/tip" system ensures utmost accuracy and ...
... Carl Zeiss is expanding the borders ... field, excellent color reproduction, high-contrast images ... patented optics provide improved resolution and ... (Systems Control Panel) combines all essential ...
Inquire...
Medicine Products: