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Zenobia Therapeutics, Inc. And BioBlocks, Inc. Announce Sale Of A Joint Fragment Library Ideal For Screening By All Popular Methods
Date:5/7/2012

LA JOLLA, Calif., May 7, 2012 /PRNewswire/ -- Zenobia Therapeutics, Inc. (Zenobia), the leader in fragment-based lead discovery (FBLD) for CNS diseases and FBLD/structural biology services, and BioBlocks, Inc. (BioBlocks), a leader in medicinal chemistry services and novel building block products, announced today that they are adding a 284 compound fragment library to their product offerings.  The library, ZB-Fragment Library 2, is ready for screening by all popular methods, contains soluble, verified protein binders, is shape and functionally diverse, and has an average molecular weight of 161.4 Da. The library was constructed by combining BioBlocks' unique expertise in medicinal chemistry and scaffold design with Zenobia's expertise in FBLD. Vicki Nienaber, Ph.D., President, CSO and founder of Zenobia, reported the first fragment-based crystallographic screening method (Nature Biotechnology 2000) and Robert Meadows, Ph.D. co-founder of Zenobia is an inventor of the SARbyNMR method (Science 1996). Industry veteran BioBlocks medicinal chemists have advanced numerous leads into preclinical and clinical development and have created a lead discovery platform capable of generating high quality patentable leads in a cost and time efficient manner.    

"Our customers have experienced an impressive success-rate in identifying valuable hits with Zenobia Fragment Library 1 with many returning to purchase additional copies. Establishing a collaborative relationship with BioBlocks allows us to jointly provide Fragment Library 2 with added core diversity and medicinal chemistry readiness using BioBlocks' unique expertise in creating leads from its building blocks," said Dr. Nienaber.  BioBlocks CEO, Dr. Pallai, said, "BioBlocks' core strength is the medicinal chemistry we utilize in collaborative drug discovery programs with our clients. Working with Zenobia allows us to take advantage of their unparalleled capabilities and experien
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