Navigation Links
Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome
Date:1/15/2014

ences.  Key hormones, including adiponectin and leptin, also showed changes characteristic of non-PWS obese patients, demonstrating that the drug was highly active in these patients and had a similar effect to that seen in non-PWS patients.

"These results are very exciting for the treatment of PWS, as most patients showed improvements in body weight, hunger-related behaviors, and body fat content, despite the increased food intake included in the trial design," explained Dr. Jennifer Miller, Associate Professor of Pediatric Endocrinology, University of Florida, and Principal Investigator for the study.  "PWS is a complex genetic disease that is difficult to treat and the results of this trial demonstrate that beloranib has a beneficial impact on this underserved patient population.  Notably, we were encouraged by reports of fullness, a first-time occurrence for PWS patients who otherwise lack the capacity to feel sated after meals."

"PWS patients remain severely impacted by their disease and are not treatable with other anti-obesity agents," added Janalee Heinemann, Director of Research & Medical Affairs for the Prader-Willi Syndrome Association (USA).  "PWS represents one of the most severe forms of genetic obesity and we welcome these results, which are a significant step towards finding a treatment for those suffering from this life threatening condition."

Beloranib, a novel obesity therapy that utilizes a unique mechanism of action, is being studied for its ability to reduce body weight and improve cardiometabolic risk factors in obese patients with and without PWS.  This study was a randomized, double-blind, placebo-controlled trial to evaluate the safety and tolerability of a dose range of beloranib administered as twice-weekly subcutaneous injections for four weeks.  The randomized treatment part of the study was follow
'/>"/>

SOURCE Zafgen, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Zafgen Announces Initiation of Phase 2a Clinical Development with Beloranib in Obesity
2. Zafgen Secures $21 Million in Series D Financing
3. Zafgen Announces New Weight Loss and Safety Data from Phase 2 Study of Beloranib in Obesity at Obesity Week 2013
4. Zafgen Secures $45 Million in Series E Financing
5. Zafgen Appoints Chief Commercial Officer and New Member of Board of Directors
6. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
7. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
8. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
9. Misonix Announces New Distribution Agreement For Panama
10. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
11. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... , Oct. 1, 2014 ... now available. Interested parties can learn about ... Cardinal Health is supporting the health care ... http://cardinalhealth.com/annualreport . Photo- http://photos.prnewswire.com/prnh/20140930/149504-INFO ... summary financials and the chief executive officer,s ...
(Date:10/1/2014)... (NYSE: RMD ), a pioneer and innovator in ... sleep apnea solutions specifically for women, is launching a new ... night,s sleep. The Better Sleep For Women ... just part of living a busy life. It will encourage ... health, essential to not only living an active lifestyle but ...
(Date:10/1/2014)... 1, 2014  Varian Medical Systems (NYSE: ... for the fourth quarter of fiscal year 2014 following ... 2014.  The news release will be followed by a ... PT.  The news release and a link to the ... website at: www.varian.com/investor .  To access the teleconference ...
Breaking Medicine Technology:Cardinal Health 2014 Digital Report to Shareholders Now Available 2ResMed Launches Initiative to Help Women Get Better Sleep 2ResMed Launches Initiative to Help Women Get Better Sleep 3Varian Medical Systems Schedules Fourth Quarter FY2014 News Release and Conference Call 2
... 7 The 14th Annual Webby Awards named Regence BlueCross ... of Rich Media: Business to Consumer. More than a million people ... steep competition from companies that included Doritos® and NIKE. , ... The People,s Voice win ...
... May 7 Catalyst Pharmaceutical Partners, Inc. (NasdaqCM: ... Officer, will be making a presentation at the MoneyShow Conference ... at Caesars Palace in Las Vegas .  Catalyst will ... and CPP-115. Further, the Company reported that its presentation materials ...
Cached Medicine Technology:Regence BlueCross BlueShield Wins People's Voice Award for Online Consumer Campaign in the 14th Annual Webby Awards 2Regence BlueCross BlueShield Wins People's Voice Award for Online Consumer Campaign in the 14th Annual Webby Awards 3Catalyst Pharmaceutical Partners to Present at the MoneyShow Conference 2
(Date:10/1/2014)... (PRWEB) October 01, 2014 Join the more ... Eating Disorder Treatment Center’s first ever charity golf tournament to ... people with eating disorders who cannot afford treatment. The tournament ... Club in Eureka, Mo. , The day-long event starts ... A reception and award dinner will begin at 5 p.m. ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Innovations announces ... scheduled to broadcast on Monday, October 20, 2014 at ... episode, Innovations will go behind the scenes to learn ... This segment will explore the practical help and information ... which teaches the warning signs of abuse, how to ...
(Date:10/1/2014)... Scientists at the University of Western Australia ... system proteins has the power to knock out mesothelioma ... the new study on their website. Click here ... the UWA School of Pathology and Laboratory Medicine administered ... mesothelioma with promising results. , “A timed triple ...
(Date:10/1/2014)... October 01, 2014 October is national ... and early detection plans while raising money for breast ... Breast Cancer Awareness Month in the effort to ... to promote the importance of having access to clean, ... may be linked to certain forms of cancer. ...
(Date:10/1/2014)... Two bicyclists began a journey on ... country in an effort to raise funds and awareness ... cyclists, a father-daughter team, plan to bike more than ... and finishing in Key West Florida. Funds raised ... a national nonprofit organization that assists post-9/11 service members, ...
Breaking Medicine News(10 mins):Health News:Project HEAL Benefit Golf Tournament Gaining Momentum 2Health News:Project HEAL Benefit Golf Tournament Gaining Momentum 3Health News:Innovations to Explore Breakthroughs in Health and Wellness in Upcoming Episode Airing Monday, October 20, 2014 via Discovery Channel 2Health News:New Mesothelioma Study Says Mice Cured by Immuntherapy “Cocktail”, Reports Surviving Mesothelioma 2Health News:Pelican Water Supports Breast Cancer Awareness Month with Order Donations 2Health News:Father-Daughter Cycling Duo to Ride Cross-Country to Benefit Hope For The Warriors 2
... Treatment Model Blends Eastern and Western Therapies to Create ... ... Feb. 13 Moonview Sanctuary, the exclusive,non-residential treatment and ... approaches practiced by more than 70,experts in their fields, ...
... SUINING, China, Feb. 13 /Xinhua-PRNewswire/ -- China Health ... that Jia Minru, famous,professor of the Chinese Medicine ... be responsible for deep development,high-tech development and systematic ... The joining of Jia Minru will certainly ...
... Calif., Feb. 12 Blue Cross of California,highly values ... members have with their physicians and medical groups. It ... and up to date,both for the benefit of our ... the ways we do this is to send the ...
... Event Name ... Same Commitment to ... the Health of all Babies, CINCINNATI, ... announce that 4-year-old Bradley,Coffey of Kennedy Heights and his family will serve ... as WalkAmerica,March for Babies is the March of Dimes premier fundraising event ...
... (OTC Bulletin Board: ECTE), a specialty pharmaceuticals and,diagnostics ... approximately,$2.3 million private financing with Montaur Capital through ... select institutional and strategic,investors of senior unsecured convertible ... principal amount of Senior Convertible,Notes to be issued ...
... 12 Edwards Lifesciences,Corporation (NYSE: EW ), the ... that it has filed a patent infringement lawsuit against,CoreValve, ... Court for,the District of Delaware. The suit seeks injunctive ... family of patents for transcatheter,heart valve technology., "Edwards ...
Cached Medicine News:Health News:High-End Treatment Center Moonview Sanctuary Unveils Four New Core Treatment Programs 2Health News:High-End Treatment Center Moonview Sanctuary Unveils Four New Core Treatment Programs 3Health News:Renowned Chinese Herbal Medicine Development Specialist Joins China Health Resources 2Health News:Local Families Chosen for Ambassador Role for 2008 March for Babies 2Health News:Local Families Chosen for Ambassador Role for 2008 March for Babies 3Health News:Echo Therapeutics Announces Closing of Approximately $2.3 Million Private Financing 2Health News:Echo Therapeutics Announces Closing of Approximately $2.3 Million Private Financing 3Health News:Edwards Lifesciences Initiates Patent Infringement Litigation Against CoreValve in the U.S. 2