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YM BIOSCIENCES ANNOUNCES NIMOTUZUMAB PRESENTATIONS TO BE MADE AT THE 100TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH AND EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY
Date:3/13/2009

ximab against EGFR-overexpressing tumors.

    European Society for Medical Oncology (ESMO) Presentation, March 23-25,
    2009

Additionally, YM announced that a further poster entitled "Differences in clinical safety profiles of nimotuzumab and cetuximab, EGFR-targeting antibodies, as a consequence of divergent monovalent/bivalent binding profiles of these agents" has been accepted for presentation at the European Society for Medical Oncology's 7th International Symposium on Targeted Anticancer Therapies 2009 in Amsterdam, Netherlands being held March 23rd - 25th, 2009 (Abstract code C02).

"The three posters referenced are a partial reflection of the current, extensive activity at YM, its licensees and at other nimotuzumab developers worldwide aimed at explaining the benign toxicity profile of nimotuzumab given its established anti-tumour activity," said David Allan. "We believe that these compelling results, combined with the evidence of efficacy of nimotuzumab in the correct settings, and with the appropriate regimens, should convince investors that the market is inappropriately discounting the value of the nimotuzumab clinical program."

YM is conducting two international, multi-center, randomized, double-blinded Phase II trials with nimotuzumab in combination with radiation. These two indications - brain metastasis from lung cancer and palliative therapy in non-small cell lung cancer (NSCLC) - represent indications of high unmet need. In the US, approximately 140,000 cases of brain metastasis are diagnosed annually and the frequency is increasing as more patients live longer. The incidence of lung cancer in the US is approximately 215,000 cases of which 80-85% is NSCLC. Recruitment of these trials is expected to be complete in 2010.

Notice for AIM Compliance

The Company was notified on 27 February 2009 that on 17 February 2009, Mr. Gabe Hoffman directly and through Accipi
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