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Xcovery Vision Founders to Speak at ARVO 2011
Date:4/25/2011

cted alone and this number is projected to double by 2020.  The macula is part of the retina responsible for central vision, and AMD is characterized by slow deterioration of central visual acuity.  Approximately 5-10% of patients with AMD develop abnormal blood vessel growth underneath the macula which leak and distort vision.  This is known as "wet" (exudative) AMD.  Current treatments for wet AMD involve monthly injections of medication directly into the eye.  

About XV-615

XV-615 is novel tyrosine kinase inhibitor with dual activity against the vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR). Xcovery Vision is developing XV-615 as an extended-release intravitreal injection for wet AMD.  Preclinical studies to date demonstrate safety, efficacy and formulation properties that are ideal for ophthalmic applications.  XV-615 has the potential to improve efficacy for treatment of wet AMD because it targets two synergistic pathways mediated by VEGFR and PDGFR.  As an extended-release formulation, XV-615 also has the potential to improve safety by reducing the frequency of injections into the eye.

About Xcovery Vision

Xcovery Vision is an ophthalmology therapeutics company founded in 2010 as subsidiary of Xcovery, LLC.  Its core focus is to repurpose Xcovery's pipeline of novel kinase inhibitors for ophthalmic indications.  For more information about Xcovery Vision please visit www.xcoveryvision.com.

Contact:
Teri Swift
Vice President of Business Development
(561) 835-9356
teri@xcoveryvision.com


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