Navigation Links
Xcovery Vision Founders to Speak at ARVO 2011

WEST PALM BEACH, Fla., April 25, 2011 /PRNewswire/ -- The ophthalmic therapeutics company Xcovery Vision announced today that Sheridan G. Snyder, OBE, Chairman and CEO, and Dr. Ken Mandell, President and COO, will be speaking at The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting in Fort Lauderdale Florida, May 1-5, 2011.  Mr. Snyder's talk Perspective of a Serial Entrepreneur recounts his repeated success as founder of multiple biotech companies that include Genzyme, Upstate Biotechnology, Biotage and Molecular MD.  

Dr. Ken Mandell will present preclinical study results with Xcovery Vision's novel angiogenesis inhibitor XV-615 currently being developed for age-related macular degeneration (AMD). This study Intravitreally Delivered VEGFR/PDGFR Inhibitor XV-615: Safety Assessment in Rabbits was conducted in collaboration with Massachusetts-based ocular therapeutics company EyeGate Pharma (

About the Ophthalmology Drug Market

Ophthalmic drugs constitute a prominent segment of the global pharmaceutical market. From 2003 to 2008, sales of ophthalmic medications nearly doubled from $2.9 billion to $5.2 billion in the U.S. alone. Globally, ophthalmic pharmaceuticals are growing at annual rate of 6% and expected to reach $33 Billion by 2023. This growth has been attributed in part to the aging population in which the prevalence of diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma and dry eye syndrome are steadily rising.  There is therefore an increasing need for novel therapies to provide treatment to this growing patient population.

About Age-related Macular Degeneration (AMD)

AMD is the leading cause of blindness in patients over 55 in the United States and affects 50 million people worldwide.  More than 10 million people in U.S. are currently affected alone and this number is projected to double by 2020.  The macula is part of the retina responsible for central vision, and AMD is characterized by slow deterioration of central visual acuity.  Approximately 5-10% of patients with AMD develop abnormal blood vessel growth underneath the macula which leak and distort vision.  This is known as "wet" (exudative) AMD.  Current treatments for wet AMD involve monthly injections of medication directly into the eye.  

About XV-615

XV-615 is novel tyrosine kinase inhibitor with dual activity against the vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR). Xcovery Vision is developing XV-615 as an extended-release intravitreal injection for wet AMD.  Preclinical studies to date demonstrate safety, efficacy and formulation properties that are ideal for ophthalmic applications.  XV-615 has the potential to improve efficacy for treatment of wet AMD because it targets two synergistic pathways mediated by VEGFR and PDGFR.  As an extended-release formulation, XV-615 also has the potential to improve safety by reducing the frequency of injections into the eye.

About Xcovery Vision

Xcovery Vision is an ophthalmology therapeutics company founded in 2010 as subsidiary of Xcovery, LLC.  Its core focus is to repurpose Xcovery's pipeline of novel kinase inhibitors for ophthalmic indications.  For more information about Xcovery Vision please visit

Teri Swift
Vice President of Business Development
(561) 835-9356

SOURCE Xcovery Vision
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. New Localized Cancer Treatment for Advanced Retinoblastoma Saves Children From Having Eyes Removed, Restores Vision in Some Cases
2. Dr. Calvin Grant Presents Results from Xibrom(TM) Combination Therapy with Lucentis(R) at the 2008 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
3. Gene Therapy Provides Vision to People who Were Nearly Blind
4. Gene Therapy Improves Vision in Patients with Congenital Retinal Disease
5. Strykers Biotech Division Receives FDA Warning Letter
6. Menicon Undertakes With the Novovision Clinic a Paediatric Myopia Control Clinical Trial
7. Vision Problems Affect How Children Learn Math Skills
8. TOZAL(R) Nutritional Supplement Improves Vision in Common Form of Macular Degeneration
9. Harvard Study Shows Folic Acid, B Vitamins in Animi-3(R) May Prevent Vision Loss
10. Sirion Therapeutics Announces Clinical Data Presentations at the 2009 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
11. Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting
Post Your Comments:
(Date:12/1/2015)... 1, 2015 Building on its 25-year ... Johnson (NYSE: JNJ ) today announced four ... to significantly reduce the burden of HIV incidence, ... percent of new HIV infections among adolescents in ... Day, these new initiatives include collaborations with the ...
(Date:12/1/2015)... York , December 1, 2015 /PRNewswire/ ... Pills, Contraceptive Injectables, Topical Contraceptives, Male Condoms, ... Contraceptive Vaginal Rings, Contraceptive Diaphragms, Contraceptive Sponges, ... Analysis, Size, Share, Growth, Trends and Forecast ... by Transparency Market Research (TMR).The report states ...
(Date:12/1/2015)... ATLANTA , Dec. 1, 2015   ... automated value cycle solutions, today announced the company ... Pharmacy ChargeLink ® solution at ... 2015 Midyear Clinical Meeting . The new features ... complicated process of monitoring and managing enterprise-wide pharmacy ...
Breaking Medicine Technology:
(Date:12/1/2015)... FL (PRWEB) , ... December 01, 2015 , ... ... announces the Multi Jar, a container patent that allows for easier packing and organizing ... the US is worth $90 billion," says Scott Cooper, CEO and Creative Director of ...
(Date:12/1/2015)... ... ... Hospital Tampa is the first health care provider in the region to offer the ... is a vagal blocking therapy, delivered via the Maestro® System, for the treatment of adult ... least 40 to 45 kg, or a BMI of at least 35 to 39.9 kg ...
(Date:12/1/2015)... Houston, TX (PRWEB) , ... December 01, 2015 , ... ... owner of Vitenas Cosmetic Surgery, has been named by MedEsthetics magazine as the Best ... best of the best among the many elite aesthetic physicians honored by the industry ...
(Date:12/1/2015)... Delaware (PRWEB) , ... December 01, 2015 , ... ... winner at the 7th Annual 2015 Golden Bridge Business Awards under the New ... is a zero capex web based sample management software that helps ...
(Date:12/1/2015)... ... December 01, 2015 , ... For many X-rays ... film for accurate interpretation by the radiologist. The marking utensils are so small, ... Calif., has found a way to alleviate this problem. , He developed the ...
Breaking Medicine News(10 mins):