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XBiotech Reports Positive Phase II Interim Analysis Results in Vascular Disease
Date:11/20/2012

le and safe monoclonal antibody therapy into current treatment practices has the potential to provide significant benefit to patients and a new option for endovascular surgeons."

"Vascular inflammation is the cause of vascular diseases such as atherosclerosis," said Michael Stecher, M.D., Medical Director, XBiotech. "Our MABp1 therapy blocks a key mediator of vascular inflammation. Patients with advanced arterial disease treated with MABp1 after revascularization have shown reduced arterial occlusion and reduced overall complications from the disease.  Based on the interim results, we believe MABp1 may ultimately provide a treatment for millions of patients suffering with vascular disease."

About True Human™ Antibodies

True Human™ antibodies represent the next generation of therapeutic antibodies.  These antibodies are identified using the Company's proprietary platform technology to ensure faithful reproduction of the original human antibody gene.  True Human antibodies are "invisible" to the body's immune system and thus have the potential for better safety, efficacy and patient tolerability compared to earlier generation antibody therapeutics.

About XBiotech

XBiotech is pioneering breakthrough therapies that improve the safety and efficacy of antibody therapeutics. The Company's lead product candidate inhibits chronic sterile inflammation by targeting IL-1a, a master regulator of inflammation. The clinical development program addresses tremendous unmet medical need in multiple disease indications including, acne, psoriasis, cachexia, cancer, type 2 diabetes and cardiovascular disease. XBiotech is also revolutionizing scalable, flexible manufacturing systems for the production of biological therapies.  Using minimal infrastructure and disposable bioreactor technology – to dramatically reduce capital requirements, operating complexity, and lead times -
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