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XBiotech Reports Positive Phase II Interim Analysis Results in Vascular Disease
Date:11/20/2012

AUSTIN, Texas, Nov. 20, 2012 /PRNewswire/ -- XBiotech, a privately held biotechnology company, announced positive interim analysis results today from a Phase II study in patients receiving MABp1 to reduce restenosis after percutaneous revascularization of the Superficial Femoral Artery (SFA).  Patients receiving MABp1 demonstrated a 58 percent reduction in Major Adverse Cardiovascular Events (MACE) and 60 percent longer patency in treated vessels compared to control patients. This is the first report of MAB therapy in restensois and fourth clinical indication where the Company's lead candidate, MABp1, has demonstrated strong safety and effectiveness. Positive results in cachexia, psoriasis, and type 2 diabetes have also recently been reported by XBiotech.

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The Phase II clinical study is a randomized, open-label multi-center trial involving some of the most prestigious cardiac hospitals in the country. The study  is being lead by Hosam El-Sayed, M.D., Ph.D., R.V.T, Assistant Professor of Cardiovascular Surgery, Weill Cornell Medical College, Methodist DeBakey Heart and Vascular Center, The Methodist Hospital, Houston, Texas.  Dr. El-Sayed's career includes positions as Assistant Professor of Surgery in the Vascular Surgery Division of Baylor College of Medicine and the Michael E. DeBakey VA Medical Center, Assistant Professor of Surgery at the University of Cincinnati, and Vascular Surgery Chief a
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