Navigation Links
XBiotech Announces it is Developing Therapy for MRSA

AUSTIN, Texas, Sept. 4, 2013 /PRNewswire/ -- XBiotech announced today that it has completed discovery and has begun pre-clinical development of a new True Human™ antibody therapy for methicillin resistant staphylococcus aureus (MRSA). The new antibody therapy is expected to be effective at neutralizing drug resistant staphylococcus infection by circumventing key immune evasion strategies of the bacteria, thereby facilitating natural clearance of the bacteria by the patient's own immune system. The Company believes that the therapy could represent a breakthrough in the management of infectious disease. XBiotech reports that the MRSA antibody came out of its True Human™ antibody discovery program for identifying and cloning pharmacologically relevant antibodies from human donors. XBiotech expects this product candidate to enter human clinical trials next year.

One-third of the world's population is believed to have S. aureus bacteria present on or in their bodies (particularly nasal cavities). It is estimated that 2.7% of these cases are MRSA strains which, under certain situations, can cause severe infections such as so called "flesh-eating" disease, necrotizing pneumonia, infective endocarditis, or more commonly impetigo, cellulitis and abscesses. In the US, community acquired MRSA infections have been reported to occur in 25.7/100,000 persons annually, whereas with respect to nosocomial infections, as many as 60% have been reported to be MRSA. Lethal MRSA infections have increased dramatically, killing 30-fold higher numbers of patients in the UK in 2006 compared to just over a decade earlier.

The Company's CEO, John Simard said, "To date, XBiotech has made significant strides on the discovery and development of anti-inflammatory antibodies. We are now truly excited about the possibility of revolutionizing the management of infectious disease through the use of shared natural immunity with True Human™ therapeutic antibodies. Needles to say, we are eager to see this important therapy in the clinic."

XBiotech is leading the commercialization of biological therapies—including the discovery and development of True Human™ antibodies. The Company's lead product candidate—in Phase III clinical studies—is a novel, breakthrough treatment for advanced colorectal cancer. XBiotech has also developed manufacturing technology to reduce infrastructure needs, lessen capital requirements and reduce lead times for biological drugs, ushering in a new era for cost and development efficiency in the biopharmaceutical industry.

Ashley Otero

Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. XBiotech to Present at UBS Global Healthcare Conference
2. XBiotech Reports Positive Phase II Interim Analysis Results in Vascular Disease
3. XBiotech Reports Positive Phase II Interim Analysis Results From Type 2 Diabetes Study
4. Mylan Announces Completion of Transdermal Patch Facility Expansion Project in St. Albans, Vt.
5. SanBio Announces The Completion Of Enrollment Of Its Clinical Trial Of Cell Therapy For Chronic Stroke Deficits
6. Ryan & Maniskas, LLP Announces Class Action Lawsuit Against NuVasive, Inc.
7. Hamilton Regional Laboratory Medicine Program Announces Decision to Acquire COPANs WASPLab, the Next Generation Full Laboratory Automation and Digital Bacteriology System
8. IVD Technology Magazine Announces the IVD Business Strategy Conference in San Diego
9. Avanir Pharmaceuticals Announces Settlement of NUEDEXTA Patent Litigation with Actavis
10. Intra-Cellular Therapies Announces Closing of $60 Million Private Placement and Completion of Reverse Merger
11. Encision Announces Death of Chief Executive Officer Fred F. Perner
Post Your Comments:
(Date:6/24/2016)... , June 24, 2016 ... has announced the addition of the " Global ... This report ... provides an updated review, including its applications in various ... total market, which includes three main industries: pharmaceutical and ...
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
(Date:6/23/2016)...  MedSource announced today that it has selected ... of choice.  This latest decision demonstrates MedSource,s commitment ... clients by offering a state-of-the-art electronic data capture ... as the EDC platform of choice in exchange ... has long been a preferred EDC platform by ...
Breaking Medicine Technology:
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Global law ... magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition are ... , Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. ... magazine’s Code Talker Award, an essay contest in which patients and their families pay ... be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
Breaking Medicine News(10 mins):