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WorldHeart Announces Further Milestone in Miniaturized Assist Pump Development
Date:9/6/2007

OAKLAND, Calif., Sept. 6 /PRNewswire-FirstCall/ -- (Nasdaq: WHRT, TSX: WHT) World Heart Corporation (WorldHeart), a developer of mechanical circulatory support systems, announced successful completion of the first multi-day animal study of a miniaturized, pediatric, ventricular assist device (VAD). The PediaFlow(TM), developed by a National Institutes of Health-funded consortium including WorldHeart, is expected to be the platform for a future minimally invasive adult VAD, intended to meet a large clinical need for earlier-stage heart failure patients.

The animal implant was performed by Peter Wearden, M.D., Ph.D., pediatric cardiac surgeon at the Children's Hospital of Pittsburgh. The six-day study, at the University of Pittsburgh McGowan Institute, focused on hemodynamic performance and biocompatibility under physiologic conditions. The device provided uninterrupted support and met all design targets. Biocompatibility was demonstrated, with no indications of blood damage or clotting.

Dr. Harvey Borovetz, the Robert L. Hardesty Professor of Surgery, Chairman of Bioengineering at the University of Pittsburgh and Principal Investigator of the associated NIH PediaFlow development contract, remarked that, "With the success of the recent in vivo experiments, we are encouraged to begin 30-day animal implants, focusing again on pump performance and biocompatibility."

Mr. Jal Jassawalla, WorldHeart's President and CEO, commented, "The positive results of the initial in vivo implants highlight the potential benefits of WorldHeart's MagLev(TM) technology. We are excited that this technology, first embodied in the Levacor(TM) VAD, is being extended to the pediatric VAD and then potentially to a WorldHeart minimally invasive adult VAD." The latter, providing partial circulatory support, would serve a broad population with less advanced heart failure. Such a device would complement WorldHeart's Levacor VAD, which is intended to provide a greater degree
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SOURCE World Heart Corporation
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