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Voices Against Brain Cancer Awards Grant to Tocagen to Support Investigation of Toca 511 & Toca FC in Patients with Recurrent Brain Cancer
Date:6/19/2013

ission is to help find a cure for brain cancer and brain tumors by advancing scientific research, increasing awareness within the medical community and supporting patients, their families and caregivers affected by this devastating disease.

Voices Against Brain Cancer has a wide variety of initiatives in place for brain cancer research, awareness and support. The organization is committed to ensuring that the proceeds of the monies donated are used to fund cutting-edge research that will have a monumental impact on the diagnosis and treatment of brain cancer. Currently, these grants are being funded at numerous esteemed institutions including: Columbia, Cornell, Duke, Harvard, John Hopkins, MD Anderson, Memorial Sloan Kettering, New York University, Yale and more.

For more information please visit: www.voicesagainstbraincancer.org

About Toca 511 & Toca FC
Tocagen Inc., the clinical trial sponsor, is developing the investigational drug Toca 511 (vocimagene amiretrorepvec) in combination with Toca FC (an investigational extended-release formulation of 5‑FC) for the treatment of recurrent high grade glioma, including glioblastoma multiforme (GBM, Grade IV glioma), the most common and aggressive form of brain cancer. Toca 511 is a retroviral replicating vector (RRV) encoding the genetic instructions for the enzyme cytosine deaminase (CD). Toca 511 is designed to selectively infect dividing cancer cells and spread through the tumor after administration. Each patient then begins a course of Toca FC. Within Toca 511-infected cells the CD enzyme converts 5‑FC to the anti-cancer drug 5‑FU. By producing 5‑FU locally, this technology has the potential to pr
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SOURCE Voices Against Brain Cancer
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