Navigation Links
Vitamin E Improves NASH
Date:10/31/2009

ALEXANDRIA, Va. and BOSTON, Oct. 31 /PRNewswire/ -- In a randomized, double-blind, placebo-controlled trial of 247 patients who had NASH but not diabetes, pioglitazone improved key histological features and liver enzymes; however, vitamin E was more successful for the treatment of NASH in these patients.

NASH is associated with fatty liver disease, insulin resistance, and obesity, and it is estimated that 3 to 4 percent of Americans have NASH. The disease progresses to inflammation in the liver and in 15 to 20 percent of those patients to cirrhosis. There is no current treatment for this common disease.

In this study presented at the annual meeting of the American Association for the Study of Liver Diseases, patients were randomized into three groups and given pioglitazone (an insulin-sensitizer), vitamin E, or a placebo. At the end of the study, 19 percent of patients in the placebo group, 34 percent in the pioglitazone group, and 43 percent in the vitamin E group met the primary endpoint, which was a predetermined histological improvement and no worsening of fibrosis.

According to the study's author, Arun Sanyal, MD, of the Virginia Commonwealth University, vitamin E for the treatment of NASH had shown some success in smaller studies, but this was the first large study to be successful. The upside to this, according to Dr. Sanyal, is that, "Not only did vitamin E improve liver function in 40 percent of the patients treated with it, but the specific type of vitamin E used in the study is inexpensive, readily available, and caused no side effects in patients who participated in the study."

Abstract title:

A randomized controlled trial of Pioglitazone or vitamin E for nonalcoholic steatohepatits (PIVENS)

AASLD is the leading medical society focused solely on advancing the science and practice of hepatology and represents more than 3,300 practitioners, researchers, and allied health p
'/>"/>

SOURCE American Association for the Study of Liver Diseases
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. FDA: Procter & Gamble Unlawfully Marketing Two Vicks Cold and Flu Medicines Containing Vitamin C
2. VitaminSpice Appoints Dr. Richard F. Seelig as Director
3. July 2009 Mayo Clinic Womens HealthSource Highlights Food Storage Safety, Energy Therapies and Vitamins and Minerals
4. Study Suggests Vitamin D Screening and Appropriate Supplementation Indicated for All Cancer Patients
5. Researchers Say More Aggressive Vitamin D Supplementation Needed in Obese Cancer Patients
6. Harvard Study Shows Folic Acid, B Vitamins in Animi-3(R) May Prevent Vision Loss
7. Evidence Lacking in Multivitamin Study of Womens Risk of Cancer, Heart Disease or Death, Says Natural Products Association
8. Mission Pharmacal Launches CitraNatal(R) Assure Prescription Prenatal Vitamin
9. Emisphere Presents Dramatic Clinical Evidence Demonstrating New Approach to Vitamin B12 Supplementation
10. Scientists Reveal Roadmap to Brain Health That Can Be Passed Down to Future Generations: Exercise, Omega-3, Folic Acid, Vitamin B6, and Vitamin B12
11. Free Prostate Cancer Seminar in Lake Ridge, VA: Dr. Charles Snuffy Myers Announces Vitamin D Clinical Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... Calif. , July 29, 2015  Efforts to ... growth strategy of pharmaceutical firms in North ... The realization is that an effective working capital management ... pressures and patent cliffs. Big pharma companies expect to ... Logo - http://photos.prnewswire.com/prnh/20150724/241957LOGO ...
(Date:7/28/2015)... 2015 Codman Neuro*, part of DePuy Synthes ... platform of embolic coils for the treatment of brain ... improve microcatheter stability and provide an optimized detachment zone ... at the Society of NeuroInterventional Surgery (SNIS) 12 th ... filling and finishing coils used during a minimally invasive ...
(Date:7/28/2015)... , July 28, 2015   Regulus Therapeutics Inc ... the discovery and development of innovative medicines targeting microRNAs, ... highlights for the quarter ended June 30, 2015 on ... close. Regulus will host a conference ... 5:00 pm Eastern Daylight Time to discuss its second ...
Breaking Medicine Technology:Working Capital Management Seizes Priority in North American and European Pharma Industry 2Working Capital Management Seizes Priority in North American and European Pharma Industry 3Working Capital Management Seizes Priority in North American and European Pharma Industry 4Codman Neuro Launches Family Of Coils For Treatment Of Brain Aneurysms 2Codman Neuro Launches Family Of Coils For Treatment Of Brain Aneurysms 3Codman Neuro Launches Family Of Coils For Treatment Of Brain Aneurysms 4Regulus Announces Timing for Second Quarter 2015 Financial Results Webcast and Conference Call 2Regulus Announces Timing for Second Quarter 2015 Financial Results Webcast and Conference Call 3
... Incorporated (Nasdaq: VPHM ) today announced initiation ... safety and efficacy of C1 Esterase Inhibitor [Human] for ... of donor-specific cross-match positive kidney transplants. ... safety, tolerability and clinical effect of C1 Esterase Inhibitor ...
... SIAL ) announced the release of the first ... site has been redesigned to support and enhance scientific workflow ... information, tools, products and services they need to accelerate research ... innovative upgrades to the site over the next twelve months. ...
Cached Medicine Technology:ViroPharma Initiates Phase 2 Study of C1 Esterase Inhibitor [Human] for Treatment of Antibody-Mediated Rejection (AMR) 2ViroPharma Initiates Phase 2 Study of C1 Esterase Inhibitor [Human] for Treatment of Antibody-Mediated Rejection (AMR) 3ViroPharma Initiates Phase 2 Study of C1 Esterase Inhibitor [Human] for Treatment of Antibody-Mediated Rejection (AMR) 4ViroPharma Initiates Phase 2 Study of C1 Esterase Inhibitor [Human] for Treatment of Antibody-Mediated Rejection (AMR) 5Sigma-Aldrich Unveils Dynamic New Web Presence 2Sigma-Aldrich Unveils Dynamic New Web Presence 3
(Date:7/29/2015)... , ... July 29, 2015 , ... San Fernando ... on Ultherapy. For a limited time only, patients can get the complete treatment process ... for patients who prefer a non-invasive treatment and have loose or sagging skin. ...
(Date:7/29/2015)... ... ... are privileged to announce that U.S. News & World Report has ranked the ... the nation for 2015-2016. This marks the 21st consecutive year that the USC Eye Institute ... honor to be included in the top 10 ophthalmology hospitals by U.S. News & World ...
(Date:7/29/2015)... ... , ... A June 10, 2015 article from the News-Press, entitled " It's ... having regular skin cancer screenings from an early age. Skin cancer can strike at ... early, skin cancer is rarely fatal; however, if left alone for too long, the ...
(Date:7/29/2015)... ... July 29, 2015 , ... TransFlip is an all new dynamic transition pack ... for FCPX, these transitions are easy to apply and modify for any skill-level user. ... over 60 preset styles, kinetic flipping panel animations are just a few clicks away. ...
(Date:7/29/2015)... ... ... " mybody ” was featured on NewsWatch as part of its monthly Biz ... in their industry. Andrew Tropeano, the host of NewsWatch and business expert, conducted the ... to strengthen the skin’s defense system from the inside out. , According to Statista, ...
Breaking Medicine News(10 mins):Health News:San Fernando Valley Dermatology Office, Castle Dermatology Institute, is Now Offering a Promotional Price on Ultherapy 2Health News:21 Years & Counting: The USC Eye Institute Ranks in the Top 10 Ophthalmology Hospitals in America 2Health News:21 Years & Counting: The USC Eye Institute Ranks in the Top 10 Ophthalmology Hospitals in America 3Health News:Get Checked for Skin Cancer Early and Often 2Health News:Get Checked for Skin Cancer Early and Often 3Health News:Pixel Film Studios Releases FCPX Transition TransFlip for FCPX 2Health News:Strengthen the Skin’s Defense System from the Inside Out with mybody 2
... 2010 The American Society for Gastrointestinal Endoscopy ... its program specifically dedicated to promoting quality in endoscopy, ... United States. The ASGE Endoscopy Unit Recognition Program honors ... quality assurance, endoscopy reprocessing and CDC infection control guidelines. ...
... , ... to Win Trip to LA Film Festival , ... Wellesley, MA (PRWEB) February 10, 2010 -- “ Ban Asbestos Now ... States, today launched the Ban Asbestos Now Video Search, asking citizens across the United States ...
... women don,t believe infection can happen to them , WEDNESDAY, Feb. ... girls should still wanna have fun, they just shouldn,t overlook their ... Lady Gaga are teaming up on a new campaign -- sponsored ... that the virus that causes AIDS remains a potent threat to ...
... type 2 diabetes who take a commonly prescribed class of medications ... developing bone fractures. After taking a thiazolidinedione (TZD) for one ... fracture than patients not taking TZDs, according to study results. And ... women older than 65. "Older women are already at ...
... sporting gaze towards Vancouver for the 2010 Winter Olympics, ... the occasion with a special issue exploring the biological ... win gold. "When most people think about these ... high mountains", said co-editor Mike White from the University ...
... Finds Voters Prefer Tobacco Tax to Other Tax Increases, Budget Cuts ... Colorado ,s cigarette tax by $1 per pack ... to help close the state,s budget shortfall, while also reducing smoking ... a coalition of public health organizations. , (Logo: http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO ...
Cached Medicine News:Health News:ASGE recognizes 32 endoscopy units for quality and safety 2Health News:Nationwide Video Search Kicks off Ban Asbestos Campaign 2Health News:Nationwide Video Search Kicks off Ban Asbestos Campaign 3Health News:Cyndi Lauper, Lady Gaga Put Spotlight on Women and HIV 2Health News:Cyndi Lauper, Lady Gaga Put Spotlight on Women and HIV 3Health News:Cyndi Lauper, Lady Gaga Put Spotlight on Women and HIV 4Health News:Diabetes drug ups risk for bone fractures in older women 2Health News:Exploring the limits: Understanding the challenges facing Winter Olympic champions 2Health News:New Report: $1 Cigarette Tax Increase Would Raise $113.9 Million for Colorado and Cut Youth Smoking 2Health News:New Report: $1 Cigarette Tax Increase Would Raise $113.9 Million for Colorado and Cut Youth Smoking 3
... St. Jude Medical is the world ... introducers are used worldwide for permanent ... venous catheter and port implantation, and ... design of St. Jude Medical Peel-Away ...
This unique hemostatic seal provides a simple option for beating heart CABG anastomoses, allowing you to use your own hand-suturing technique without the release of cerebral emboli associated with th...
The RX HERCULINK® PLUS Biliary Stent System is Guidant's high performance .014" guide wire compatible system. It is available in stent diameters of 4.0-6.5mm for the 12mm stent length and 4.0-7.0...
... The OMNILINK®.035 Biliary Stent System is a supportive .035" ... 5.0 - 10.0 mm in lengths of 18 mm, ... - 7.0 mm diameters available in 12 and 16 ... available in 18mm lengths. Two "diameter specific" OMNILINK® ...
Medicine Products: