Navigation Links
ViroPharma Initiates Phase 2 Study of VP 20621 for Prevention of Recurrence of Clostridium difficile Infection (CDI)
Date:5/19/2011

rupt the normal gastrointestinal flora which renders individuals susceptible to C. difficile colonization.  Orally-dosed liquid VP 20621 utilizes non-toxigenic spore-based technology as a potential means of recolonization and protection. The goal of VP 20621 dosing following antibiotic exposure is to colonize with this non-toxigenic strain of C. difficile and to prevent colonization and infection with toxigenic strains, thereby preventing disease. VP 20621 may have therapeutic utility in the prevention of recurrence following treatment of acute CDI and in the primary prevention of CDI.  A Phase 1 escalating dose study included healthy subjects above 60 years of age who were pre-dosed with oral vancomycin to disrupt their gastrointestinal flora and render them potentially susceptible to C. difficile colonization. In this study, all subjects who received VP 20621 had positive non-toxigenic C. difficile stool cultures by day 6, suggesting that VP 20621 rapidly colonizes the susceptible GI tract.  The most common side effects observed following multiple doses of VP 20621 were mild loose or watery stools on a single study day that resolved despite continued dosing, mild burning sensation on the tongue, and mild dyspepsia.

About Vancocin® (vancomycin hydrochloride capsules, USP)

Vancocin® Capsules (vancomycin hydrochloride capsules, USP) is the only antibiotic approved to treat two significant bacterial infections of the lower digestive tract. It is administered orally for treatment of enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains) and antibiotic-associated pseudomembranous colitis caused by Clostridium difficile. Vancocin Capsules are contraindicated in patients with known hypersensitivity to vancomycin.

To reduce the development of drug-resistant bacteria and maintain
'/>"/>

SOURCE ViroPharma Incorporated
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. ViroPharma to Present at Three Upcoming Healthcare Conferences
2. ViroPharma to Present at the Natixis Bleichroeder Conference
3. ViroPharma To Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference
4. ViroPharma to Release 2008 First Quarter Financial Results on April 30, 2008
5. ViroPharma Announces Discontinuation of HCV-796 Development
6. ViroPharma Announces Completion of Enrollment in Phase 3 Study of Maribavir in Stem Cell Transplant Patients
7. ViroPharma Incorporated Completes Acquisition of Lev Pharmaceuticals
8. ViroPharma Announces Presentation of Cinryze(TM) Data in Acute Treatment of Hereditary Angioedema
9. ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients
10. ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance
11. ViroPharma Incorporated Reports Third Quarter 2009 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... BURLINGTON, Mass. , Aug. 27, 2014 /PRNewswire/ ... six different specialties (medical oncology, hematology-oncology, rheumatology, gastroenterology, ... of clinical trials that a biosimilar has been ... which biosimilar product they choose to prescribe. ... Advisory Service report entitled Acceptance of ...
(Date:8/27/2014)... -- Decision Resources Group finds that the intense physician ... health system and hospital sector in recent years ... Le Bonheur Healthcare and Baptist Memorial Health Care pulling ... In addition, a national contract recently signed between Tenet ... in the Memphis market, sets ...
(Date:8/27/2014)... , Aug. 27, 2014 By now, if ... likely not living on this planet. The awareness campaign has ... and has helped to raise over $88.5 Million (and counting) ... involved and some companies are starting to as well. ... Orlando, Florida , who actually works with ALS ...
Breaking Medicine Technology:Surveyed Physicians Expect to Choose Between Future Biosimilars Based on Robustness and Number of Clinical Trials 2Memphis-area Health Systems Turn Attention to Clinical Integration 2Acorn Stairlifts Gives a Lift to the ALS Ice Bucket Challenge 2
(Date:8/28/2014)... Now in its 4th year, Step for Hope ... brain aneurysm survivors. The ongoing mission of Step for Hope ... increase early detection and to help support individuals and families ... that you will be able to join this remarkable event ... for Hope Run/ Walk on Saturday, September 6, 2014. ...
(Date:8/28/2014)... Coveros, Inc., the market leader ... has partnered with InfoZen on the contract that ... of 2/4/2014 with U.S. Citizenship and Immigration Services ... that oversees lawful immigration to the United States. ... automate the integration and delivery of critical immigration ...
(Date:8/28/2014)... Aurora, Colo. (PRWEB) August 28, 2014 ... introduces a fun-loving man from Tallahassee, Fla. He’s a ... Broadway, but his 448-pound frame has made achieving that ... weight loss transformations, “Extreme Weight Loss” airs Tuesday, September ... , 49-year-old Rod always wears a big smile on ...
(Date:8/27/2014)... (PRWEB) August 28, 2014 According to ... "Surgical Navigation Systems Market (Neurosurgical Navigation Systems, ENT Navigation ... Size, Share, Growth, Trends and Forecast 2014 - 2020", ... USD 218.5 million in 2013 and is expected to ... 2020, to reach an estimated value of USD 295.5 ...
(Date:8/27/2014)... (PRWEB) August 28, 2014 The National ... Pierce Dennis, DrPH, MN, RN, FAAN, became the inaugural ... for the Advancement of the Science of Nursing Education ... seven that comprise the NLN Home for Transformative Excellence, ... capital a year ago. , Under Dr. Dennis’s ...
Breaking Medicine News(10 mins):Health News:Step for Hope and Raise Brain Aneurysm Awareness 2Health News:Coveros Partners with InfoZen on USCIS Transformation Integration Award 2Health News:“Extreme Weight Loss”: Rod’s Journey Begins at the University of Colorado Anschutz Health and Wellness Center 2Health News:Surgical Navigation Systems Market Expected to Reach USD 295.5 Million Globally in 2020: Transparency Market Research 2Health News:Surgical Navigation Systems Market Expected to Reach USD 295.5 Million Globally in 2020: Transparency Market Research 3Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 2Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 3Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 4
... assistant professor of psychology in the School of Science ... Center for Aging Research affiliated scientist, has received a ... whether treatment of depression before one experiences a heart ... The research study, Beating the Blues for ...
... way to immobilise radioactive forms of iodine using a microwave, ... Sheffield. Iodine radioisotopes are produced by fission of uranium ... concern because it is highly mobile in the environment and ... cancer risk following long term exposure. Furthermore, iodine-129, which is ...
... HealthDay Reporter , MONDAY, May 23 (HealthDay News) -- Cutting ... pain and foregoing annual ECG screenings for healthy, low-risk patients ... experts say. Perhaps taking a page from David Letterman,s ... up with a "Top 5" list of action items for ...
... concern about the effects of media violence on children, ... and marketed to them. An Indiana University research study ... of such programs and their characters. In a ... , Andrew J. Weaver, an assistant professor of telecommunications ...
... that quality of life means more than just material ... to be interested in letting people,s subjective well-being guide ... in Ethiopia, a city of three million people, shows ... citizens themselves consider to make them satisfied with life. ...
... MONDAY, May 23 (HealthDay News) -- Women who gained 18 or ... three times more likely to develop gestational diabetes during their second ... the study, published in the May 23 online issue of ... to shed six or more pounds between babies cut their risk ...
Cached Medicine News:Health News:IUPUI study first to look at early treatment of depression to reduce heart disease risk 2Health News:Expert discovers simple method of dealing with harmful radioactive iodine 2Health News:Experts Issue 'Top 5' List for Better Primary Care 2Health News:Experts Issue 'Top 5' List for Better Primary Care 3Health News:New study finds that violence doesn't add to children's enjoyment of TV shows, movies 2Health News:New study finds that violence doesn't add to children's enjoyment of TV shows, movies 3Health News:What do policymakers know about the factors influencing people's well-being? 2Health News:Losing Baby Weight Cuts Odds of Pregnancy-Linked Diabetes 2
The Columbus microplate strip washer is for individual strips or whole plates.Programming and control are via an alphanumeric display. Up to 30 methods are stored for easy recall....
Easy to use , Allow for a flexible washing , Uniform and efficient , Very robust and reliable , Adjustable to all well shapes , Rack included (not autoclavable) , Autoclavable at 121C , No e...
... Embla microplate washers available ... and most cell-based assays. Embla ... probes that have been optimized ... systems are robotic compatible and ...
ELISA Microplate Washer, Manual...
Medicine Products: