Navigation Links
ViroPharma Initiates Phase 2 Study of C1 Esterase Inhibitor [Human] for Treatment of Antibody-Mediated Rejection (AMR)
Date:3/29/2011

EXTON, Pa., March 29, 2011 /PRNewswire/ -- ViroPharma Incorporated (Nasdaq: VPHM) today announced initiation of a Phase 2 clinical study to evaluate the safety and efficacy of C1 Esterase Inhibitor [Human] for the treatment of acute antibody-mediated rejection (AMR) in recipients of donor-specific cross-match positive kidney transplants.

This randomized, double blind, placebo-controlled study will evaluate the safety, tolerability and clinical effect of C1 Esterase Inhibitor [Human] for the treatment of acute antibody-mediated rejection in recipients of donor-specific cross-match positive kidney transplants. The study will enroll 20 subjects (10 study drug/10 placebo), and will be conducted at up to four (4) transplant centers in the United States.  Subjects will be assessed after two weeks of treatment for safety, PK/PD, and clinical effect and again at six months post-transplant for graft function and patient survival.  

"Each year, thousands of kidney failure patients fail to receive a potentially life-saving transplant because of pre-existing antibodies to a prospective donor kidney," commented Marc E. Uknis, M.D., ViroPharma's medical director.  "These antibodies initiate complement-mediated inflammation and damage, better known as antibody mediated rejection, or AMR.  These patients, many of whom have a willing but incompatible live donor, are currently added to the deceased donor wait list and many will die waiting for a transplant. Current clinical therapies deal with removing antibodies from the circulation, but do not address the damage to the transplant caused by complement activation.  We have the potential with C1 esterase inhibitor - a complement inhibitor - to add to the treatment paradigms which could then permit broader access to transplantation for patients with such antibodies."

ViroPharma's C1 esterase inhibitor, com
'/>"/>

SOURCE ViroPharma Incorporated
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. ViroPharma Launches HAE and Me, A New Online Community to Unite People Living With Hereditary Angioedema
2. ViroPharma Announces Positive CHMP Opinion for Cinryze® (C1 Inhibitor [Human]) in European Union
3. ViroPharma Announces Securities Repurchase Program
4. ViroPharma to Participate in Two March Healthcare Conferences
5. ViroPharma to Release 2010 Fourth Quarter and Full Year Financial Results on February 24, 2011
6. ViroPharma to Participate in Several Upcoming Healthcare Investor Conferences
7. ViroPharma Receives Complete Response Letter for Cinryze™ (C1 Esterase Inhibitor [Human]) Industrial Scale Supplement
8. ViroPharma to Release 2010 Third Quarter Financial Results on October 27, 2010
9. ViroPharma to Present at the Jefferies 2010 Global Healthcare Conference
10. ViroPharma Announces Presentation of Data from Non-Toxigenic Clostridium difficile (VP20621) Phase 1 Study
11. ViroPharma To Participate in Two September Healthcare Investor Conferences
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... PARK, N.J. , July 30, 2015  Unichem ... voluntarily recalling one lot of Hydrochlorothiazide tablets 25 mg ... been initiated as a precautionary measure due to the ... of the product. The risk associated ... Hydrochlorothiazide tablet is the increased probability of experiencing Clopidogrel,s ...
(Date:7/30/2015)...  Amgen (NASDAQ: AMGN ) today announced the appointment ... Warburg Pincus LLC, to the Amgen Board of Directors. ... and the deep, global experience he brings in the ... Bradway , chairman and chief executive officer of Amgen. "Fred,s breadth ... well." Mr. Hassan has been Partner and Managing ...
(Date:7/30/2015)... , July 30, 2015  Growth of the ... as they bring former prescription users to the OTC ... Kline forecasts robust Rx-to-OTC switch activity over the ... emerging along with many new brands entering the market ... over the next five years (even those with low ...
Breaking Medicine Technology:Unichem Pharmaceuticals (USA), Inc. Issues a Voluntary Nationwide Recall of Hydrochlorothiazide Tablets Due to the Potential Presence of Foreign Tablets 2Amgen Announces Appointment Of Fred Hassan To Board Of Directors 2Amgen Announces Appointment Of Fred Hassan To Board Of Directors 3Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 3
... More and the Lalela Project announced today their new joint ... international celebrities are taking to the African airwaves to leverage ... message about malaria.   NightWatch is an interactive ... text messaging (SMS) to remind people to sleep under their ...
... YORK, Nov. 9, 2010 Reportlinker.com announces that a ... Proteomics - Technologies, Markets and Companies ... SummaryThis report describes and evaluates the proteomic technologies that ... diagnostics and practice of medicine in the post-genomic era ...
Cached Medicine Technology:World-Renowned Singer Youssou NDour Launches NightWatch Program 2Reportlinker Adds Proteomics - Technologies, Markets and Companies 2Reportlinker Adds Proteomics - Technologies, Markets and Companies 3Reportlinker Adds Proteomics - Technologies, Markets and Companies 4Reportlinker Adds Proteomics - Technologies, Markets and Companies 5Reportlinker Adds Proteomics - Technologies, Markets and Companies 6Reportlinker Adds Proteomics - Technologies, Markets and Companies 7Reportlinker Adds Proteomics - Technologies, Markets and Companies 8Reportlinker Adds Proteomics - Technologies, Markets and Companies 9Reportlinker Adds Proteomics - Technologies, Markets and Companies 10Reportlinker Adds Proteomics - Technologies, Markets and Companies 11Reportlinker Adds Proteomics - Technologies, Markets and Companies 12Reportlinker Adds Proteomics - Technologies, Markets and Companies 13Reportlinker Adds Proteomics - Technologies, Markets and Companies 14Reportlinker Adds Proteomics - Technologies, Markets and Companies 15Reportlinker Adds Proteomics - Technologies, Markets and Companies 16Reportlinker Adds Proteomics - Technologies, Markets and Companies 17Reportlinker Adds Proteomics - Technologies, Markets and Companies 18Reportlinker Adds Proteomics - Technologies, Markets and Companies 19Reportlinker Adds Proteomics - Technologies, Markets and Companies 20
(Date:7/31/2015)... ... July 31, 2015 , ... Eldermark Software, ... LeadingAge’s Center for Aging Services Technologies (CAST) Medication Management Technologies whitepaper. The whitepaper ... care providers understand the benefits of using medication management technologies . ...
(Date:7/31/2015)... McLean, VA (PRWEB) , ... July 31, 2015 , ... ... solution at OSEHRA 2015. , What is HITaaS? Health IT as a Service (HITaaS) ... (IaaS) and software as a service (SaaS). , HITaaS manages all aspects ...
(Date:7/31/2015)... ... 31, 2015 , ... Physical therapy for knee osteoarthritis is an important ... It keeps the patient from doing what they want or need to do. The patient ... using the stairs. The patient's exercise regime may be limited by the pain in their ...
(Date:7/31/2015)... ... , ... New Energy Works Timberframers invites the public to join their timber ... from 9am – 12pm. Timber frame raisings are special, celebrating both craft ... the culmination of months of effort, planning, fundraising, and dreaming takes shape. , ...
(Date:7/31/2015)... ... ... The Radiology Business Management Association’s 2015 Fall Educational Conference ... Care: A View From Capitol Hill” on Sunday, Sept. 27, 2015, in Austin, Tex. ... has a special understanding of the real world impact of health care policy issues,” ...
Breaking Medicine News(10 mins):Health News:LeadingAge Selects Eldermark Case Study to Highlight Medication Error Reduction Results 2Health News:LeadingAge Selects Eldermark Case Study to Highlight Medication Error Reduction Results 3Health News:ZH Healthcare Unveils Health IT as a Service (HITaaS) at OSEHRA 2015 2Health News:ZH Healthcare Unveils Health IT as a Service (HITaaS) at OSEHRA 2015 3Health News:ZH Healthcare Unveils Health IT as a Service (HITaaS) at OSEHRA 2015 4Health News:NYDNRehab Is the First Clinic in NYC to Provide APOS Therapy Based on Results of Complete Gait Analysis 2Health News:NYDNRehab Is the First Clinic in NYC to Provide APOS Therapy Based on Results of Complete Gait Analysis 3Health News:Timber Frame Raising: Granary District Stage Amphitheater Timber Frame Hand-Raising by New Energy Works Timberframers 2Health News:Timber Frame Raising: Granary District Stage Amphitheater Timber Frame Hand-Raising by New Energy Works Timberframers 3Health News:Congressional Health Caucus Founder Rep. Michael Burgess, MD, to Speak at RBMA Fall Educational Conference 2Health News:Congressional Health Caucus Founder Rep. Michael Burgess, MD, to Speak at RBMA Fall Educational Conference 3
... frozen ready meals including 20 Asda own brand, 4 Sainsbury’s ... may contain small pieces of glass. Customers are also being ... ,The products came from Rye Valley Foods in Carrickmacross, a ... the country's biggest food processors. The company said pieces of ...
... group from Los Angeles has pressed upon Viagra manufacturers to ... pushes the drug’s use as a recreational drug. ... by gay and bisexual men who are also patronizing methamphetamine, ... risks. The AIDS Healthcare Foundation is especially worried that this ...
... after being administered DPT (diphtheria, pertussis and tetanus) injection Saturday. ... ,According to official sources, the deaths took place ... km from here. Twelve children have been admitted to Ara ... programme was launched for children below one year of age. ...
... Breast and Bowel Project (NSABP) B-33 study, presented ... showed that// postmenopausal women with hormone receptor-positive breast ... tamoxifen were 56% less likely to have a ... placebo (P=0.004). ,“Aromasin provided patients with ...
... The prescription for an anti-smoking pill Zyban, given by a ... ,Smokers who were residents of Glasgow, were trying to ... pill. This was mistakenly read as Viagra due to a ... Greater Glasgow and Clyde said , due to an error ...
... that women treated for ovarian cancer are at increased ... their tumor cells have high// levels of a binding ... death, both hallmarks of malignancy. ,“Now there’s ... tissue removed during surgery might identify women most at ...
Cached Medicine News:Health News:New Study Shows Efficacy of AROMASIN on Early Breast Cancer 2Health News:New Study Shows Efficacy of AROMASIN on Early Breast Cancer 3Health News:New Study Shows Efficacy of AROMASIN on Early Breast Cancer 4Health News:'Clumping' Protein Linked to Return of Ovarian Cancer 2
Slightly curved 10 mm jaws and serrated cross action handle with polished finish. Overall length 4.6 inches....
Hartman Mosquito forceps, straight, 3.5"....
Curved 20 mm serrated jaws. Ring handle with ratchet lock and dull finish. Most popular size or model. Overall length 3.9 inches...
Shafts angled 45 degrees with 10 mm jaws. Serrated handle with polished finish. Crisscross serrated jaws. Most popular size or model....
Medicine Products: