Navigation Links
Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults
Date:5/26/2009

200 and 400 mg/day experienced a median percent reduction in seizure frequency per 28 days of 33.3% and 36.8%, respectively, versus only 18.4% reduction in the placebo group. Additionally, 34.1% and 39.7% of patients taking Vimpat at 200 and 400 mg/day, respectively, experienced greater than or equal to 50% reduction in seizure frequency versus only 22.6% in the placebo group.

Patients randomized to Vimpat(R) also experienced improvement in seizure freedom rates, compared with placebo. Across the pivotal trials, 3.3% of patients randomized to 400 mg/day of Vimpat(R) were seizure free throughout the 12-week maintenance phase, vs. 0.9% of placebo patients. Seizure free days increased by 8% with 200 mg/day of Vimpat(R) and by 12% with 400 mg/day of Vimpat(R), compared with 6% for placebo.

Patients began experiencing a reduction in seizures during the titration phase and maintained or had improved seizure control throughout the studies. The most common adverse events (>10 percent in the Vimpat(R)-treated group and greater than placebo) reported in these trials included dizziness, headache, nausea, and diplopia. More than half of the patients completing the clinical trials opted to continue treatment, some for longer than five years.

Vimpat(R) demonstrated efficacy and tolerability when combined with a broad range of existing AEDs, and also provided efficacy regardless of the number of concomitant AEDs. Vimpat was also studied with several commonly used medications, including digoxin, metformin, omeprazole, and an oral contraceptive (containing 0.03 mg ethinylestradiol and 0.15 mg levonorgetstrel).

Vimpat(R) dosing should start at 50 mg twice daily and may be increased to a daily dose of 200 to 400 mg per day (recommended therapeutic dosing) administered in two divided doses. Vimpat(R) is available as oral tablets and as an intravenous (IV) infusion to allow for consistent treatment in an emergency r
'/>"/>

SOURCE UCB
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Video: New Research Discovers Independent Brain Networks Control Human Walking
2. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
3. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
4. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
5. Video: Quest Diagnostics Health Trends(TM) Report Shows Significant Gap in Care for Patients With Chronic Kidney Disease
6. Video: New Results From One of the Worlds Largest Breast Cancer Trials Herald Hope for Thousands of Women
7. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
8. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
9. Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
10. Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
11. Video: Sanford Healths Journey to Cure Type 1 Diabetes Receives Major Boost
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... SAN ANTONIO , Jan. 15, 2014 Most ... take, according to a recent online survey* sponsored by ... among the National Osteoporosis Foundation online support community, ... to take medication that comes in a form other ...
(Date:1/15/2014)... , Jan. 15, 2014  Celsion Corporation (the "Company") (NASDAQ: ... received commitments from institutional investors to purchase an aggregate ... in an at-the-market registered direct offering, led by a ... into definitive purchase agreements with these investors pursuant to ...
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and ... be able to protect their most important business ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because of the ... steadfastly remains one of the most litigious industry ...
Breaking Medicine Technology:Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Intellectual Property Insurance for Medical-related Products and Services 2
(Date:4/24/2014)... the first in the world to discover a gene ... jaw. , Ameloblastoma is an odontogenic tumour with a ... often found in the posterior of the lower jaw. ... deficiencies in the jaws as well as loss of ... need for surgery and the recurrence of ameloblastoma, but ...
(Date:4/24/2014)... the first flu pandemic in the 21st century. The ... than 50 people in the country. Since 2011 the ... seasons). , Infections with influenza pH1N1 virus vary ... has recommended Tamiflu for treatment of patients with severe ... that it targets viral proteins which mutate quickly and ...
(Date:4/23/2014)... from Sub-Saharan Africa, Latin America and Caribbean islands ... new research from St. Michael,s Hospital. , The ... of Obstetrics and Gynaecology , assessed the differences ... native-born women in six high-immigration countries Australia ... Valencia) and the United States (California, New Jersey ...
(Date:4/23/2014)... looking to give exercise enthusiasts the extra nudge they ... that a cyber buddy can help. , The study, ... , is the first to indicate that although a ... a software-generated partner also can be effective. , "We ... still motivate people to give greater effort while exercising ...
(Date:4/23/2014)... have identified an important enzyme pathway that helps prevent ... chromosomes, a condition that has been directly linked to ... of biochemistry, found that near the end of cell ... ensures any breaks in DNA are fully repaired before ... daughter cells. This process helps safeguard against some of ...
Breaking Medicine News(10 mins):Health News:Pregnancy complications may be more common in immigrants from certain regions 2Health News:Cyber buddy is better than 'no buddy' 2Health News:Study identifies enzymes that help fix cancer-causing DNA defects 2
... for its complementary therapy. Silymarin, is a mixture made of ... number of active constituents called flavolignans, which protect the liver ... in the treatment of liver conditions like Cirrhosis and ... been suggested that Silymarin may also help control blood sugar ...
... the park; ,Age is grey,a toothless hag // ,Stumbling ... reflect the glory of youth and the dismal emotions that ... they shrink from the thought of greying hair, sagging flesh ... old age. ,With the changing trends, the ...
... of acquiring a sexually transmitted infection, according to the ... November issue of Pediatrics which reports the study suggests ... spreading such infections by up to 50 percent, which ... ,This study is only one of many ...
... is in a dilemma; whether to preserve the Roman ... a relative yes-sometimes //policy that gives us an effective ... on contraception, abortion and infallibility to new challenges," according ... a Catholic newspaper. ,Cardinal Javier Lozano Barragan ...
... health trusts, 300 sexual assault cases have been reported in ... ,During the period November 2003-March 2006, women have been ... England alone. Of these, patients attacked other patients in 224 ... the psychiatric wards have mixed sex. ,Mental health campaigner Marjorie ...
... across Indiana have no one to look out for them. ... homes //or in the community without any money or family ... or another condition that impairs their judgment or ability to ... explode as baby boomers age. ,There is only one ...
Cached Medicine News:Health News:A Wonder Drug From Milk Thistle 2Health News:Botox – The 'Celebrity' Dru 2Health News:Risk of STD Lowered with Circumcision 2Health News:Sexual assault cases in mixed-sex psychiatric wards on the high 2Health News:Hoosiers Live at the Mercy of Nursing Homes 2Health News:Hoosiers Live at the Mercy of Nursing Homes 3
RapidStrep A test is a qualitative test that detects group A,streptococcal antigen. The test is a rapid, in vitro assay. It is,intended for professional use to help diagnose Strep A,infection i...
The IntraStent DoubleStrut Biliary Stent represents a completely new direction in stent design. The combination of parallel struts and unique cell geometry provide unparalleled performance....
Inquire...
OneStep Midstream Urine hCG Pregnancy InstaTest is a test kit for the determination of hCG(Human Chorionic Gonadotropin) in urine specimens. This test kit is used to obtain a visual, qualitative resu...
Medicine Products: