Navigation Links
Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia
Date:12/8/2008

sing infants. Sexually active female patients taking Gleevec should use adequate contraception. If the patient does become pregnant while taking Gleevec, the patient should be advised of the potential hazard to the fetus.

Severe (NCI Grades 3/4) lab abnormalities -- including neutropenia (3.6%-48%), anemia (1%-42%), thrombocytopenia ( > 1%-33%), and hepatotoxicity (approx 5%) -- and severe adverse experiences (NCI Grades 3/4), including severe fluid retention (e.g., pleural effusion, pulmonary edema, and ascites) and superficial edema (1.3%-11%), hemorrhage (1.8%-19%), and musculoskeletal pain (2%-9%) were reported among patients receiving Gleevec*. Severe fluid retention appears to be dose-related, was more common in the advanced phase studies (where the dosage was 600 mg/day), and is more common in the elderly.

Severe congestive heart failure and left ventricular dysfunction have occasionally been reported. Most of the patients with reported cardiac events have had other co-morbidities and risk factors, including advanced age and previous medical history of cardiac disease. Patients with cardiac disease or risk factors for cardiac failure should be monitored carefully, and any patient with signs or symptoms consistent with cardiac failure should be evaluated and treated.

Dose adjustments may be necessary due to hepatotoxicity, other nonhematologic adverse reactions, or hematologic adverse reactions. Therapy with Gleevec was discontinued for drug-related adverse reactions in 2.4% to 5% of patients. Complete blood counts should be performed weekly for the first month, biweekly for the second month, and periodically thereafter as clinically indicated (for example, every 2-3 months).

A 25% decrease in the recommended dose should be used for patients with severe hepatic impairment. Patients with moderate renal impairment (CrCL = 20-39 mL/min) should receive a 50% decrease in the reco
'/>"/>

SOURCE Novartis
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13

Related medicine technology :

1. Video: New Research Discovers Independent Brain Networks Control Human Walking
2. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
3. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
4. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
5. Video: Quest Diagnostics Health Trends(TM) Report Shows Significant Gap in Care for Patients With Chronic Kidney Disease
6. Video: New Results From One of the Worlds Largest Breast Cancer Trials Herald Hope for Thousands of Women
7. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
8. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
9. Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
10. Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
11. Video: Sanford Healths Journey to Cure Type 1 Diabetes Receives Major Boost
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... 18, 2014  ADM Tronics Unlimited, Inc. (OTCQB: ... to its corporate Advisory Board for business development. ... the Harvard Medical School and Visiting Professor at ... his Masters degree in Electronics Engineering and his ... of Bologna. After spending a year as a ...
(Date:9/18/2014)... 18, 2014  ePharmaSolutions, the leading provider ... the Disruptive Innovator of the Year at ... platform. This solution includes an integrated clinical ... (eTMF), a remote monitoring application, eSource and ... screening and matching technology. The ...
(Date:9/18/2014)... , Sept. 18, 2014  Zacks.com announces the ... day the Zacks Equity Research analysts discuss the latest ... Stocks recently featured in the blog include the Avanir Pharmaceuticals ... (Nasdaq: NPSP - Free Report ), Orexigen (Nasdaq: ... MDVN - Free Report ) and Gilead (Nasdaq: ...
Breaking Medicine Technology:ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 2ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 3ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 2ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 3The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 2The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 3The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 4The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 5The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 6
... United Arab Emirates, Sept. 22 NewBridge Pharmaceuticals announced ... agreement with Orexo AB (STO: ORX) that grants NewBridge ... treatment of breakthrough cancer pain, in the Middle East ... and sell the product in these territories.  The agreement ...
... Decision Resources, one of the world,s leading research and ... to generic erosion of key agents, the colorectal cancer drug ... from more than $6.4 billion in 2009 to just under ... Italy, Spain, United Kingdom and Japan. The Pharmacor ...
Cached Medicine Technology:NewBridge Pharmaceuticals Signs Agreement for Abstral™ for the Middle East and Africa 2NewBridge Pharmaceuticals Signs Agreement for Abstral™ for the Middle East and Africa 3NewBridge Pharmaceuticals Signs Agreement for Abstral™ for the Middle East and Africa 4Owing to Generic Erosion of Key Agents, the Colorectal Cancer Drug Market Will Remain Relatively Flat Through 2019 2Owing to Generic Erosion of Key Agents, the Colorectal Cancer Drug Market Will Remain Relatively Flat Through 2019 3
(Date:9/18/2014)... September 18, 2014 According to a new ... Services Market - Global Industry Analysis, Size, Share, Growth, Trends ... services market was valued at USD 77607.7 million in 2013 ... from 2014 to 2020, to reach an estimated value of ... and services market is growing at a rapid pace due ...
(Date:9/18/2014)... September 18, 2014 The new ... boon to contractors and homeowners alike as it ... overtakes the home, causes potential health issues, and ... nationwide, the BuildClean system allows contractors to virtually ... and other standard remodeling tasks. , BuildClean removes ...
(Date:9/18/2014)... T-System Inc. today announced Holyoke Medical ... — EV™ for physicians — improving ... best-of-breed solutions, Holyoke chose T-System’s solution because not ... and reimbursement, but also its ability to integrate ... used to capture emergency department, (ED) nurse documentation. ...
(Date:9/18/2014)... the popular online supplier of funny figurines, has added a ... line. Moreover, all the company’s products are now offered with ... special offer before September 29, 2014. Customers who place bulk ... bobblehead doll ). , “We are pleased to ... make our interesting items available to all the global customers. ...
(Date:9/18/2014)... How much is a serving? , Most ... to the obesity epidemic in the United States. ... to manage portion size during the next “Healthy Eating ... House, 755 Ohltown Road, Austintown. , Registered dietician and ... and answer questions from 12:30 to 2 p.m. Oct. ...
Breaking Medicine News(10 mins):Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 3Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 4Health News:New BuildClean™ System Brings Livability Back to Home Remodeling 2Health News:New BuildClean™ System Brings Livability Back to Home Remodeling 3Health News:New BuildClean™ System Brings Livability Back to Home Remodeling 4Health News:Holyoke Medical Center ER Improves Productivity and Reimbursement with T-System 2Health News:Discounted Custom Bobbleheads Online For Sale At WowBobble.com 2Health News:HMHP Workshop Addresses Portion Control 2
... N.Y. study finds that weather warmer than 75 degrees poses ... research suggests that cocaine overdose deaths in New York City ... average weekly temperature goes past 75 degrees Fahrenheit. , ... Addiction , are based on death statistics in the city ...
... Researchers say defibrillators can be turned off on admission, ... care for people who are dying often forget to ... research has found. , Only 20 percent of more ... that they had a question on their admitting form ...
... , ... ... ... ...
... ... ... , ... , , , ...
... new study, led by researchers at the Herbert Irving ... demonstrates that acupuncture may be an effective therapy for ... are being treated with commonly used hormonal therapies. Results ... . Joint pain and stiffness are common side ...
... it possible to build supercomputers that can replicate the ... to an implantable chip for interfacing with neurons and ... nanoscience and neuroscience are now advancing each other in ... what this means was the topic of an hour-long ...
Cached Medicine News:Health News:Hearts of Hospice Patients Being Needlessly Shocked 2Health News:Hearts of Hospice Patients Being Needlessly Shocked 3Health News:American Dental Association President Testifies Before IOM Committee on Access to Oral Health Care 2Health News:American Dental Association President Testifies Before IOM Committee on Access to Oral Health Care 3Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 2Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 3Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 4Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 5Health News:Acupuncture may relieve joint pain caused by some breast cancer treatments 2
Daubenspeck sharp curette, 8....
Bruns bone curette, 9, oval, solid actagonal handle....
MRI curette, 8.5" overall length....
15" overall length, 5" handle....
Medicine Products: