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Video: New Results From One of the World's Largest Breast Cancer Trials Herald Hope for Thousands of Women
Date:12/18/2007

s the primary goal in breast cancer management. If we can stop the cancer from returning, we can save more lives, more often. These exciting long-term follow-up data show that anastrozole is a more effective treatment option than tamoxifen for postmenopausal women with hormone-sensitive early stage disease - thus it is imperative these women get the most effective treatment at the earliest opportunity after diagnosis."

Professor Forbes continued: "Prior to the ATAC trial, tamoxifen was the standard of care for women with hormone-sensitive disease, with substantial evidence to support its crucial place in practice. However, these new 100- month data from ATAC show us that compared with tamoxifen, anastrozole can significantly reduce the risk of recurrence and minimise life-threatening side effects. Most encouragingly, the data also show us that the protective effect of anastrozole lasts well beyond the standard treatment period of five years and in my opinion confirms there is no longer any rationale for prescribing tamoxifen."

A recent global survey showed that over 70% of physicians believe that telling a patient her breast cancer has come back is worse than giving a diagnosis of early breast cancer.(6) Recurrence, in the same breast, in the opposite breast or at a distant tumour site means that the cancer is more likely to be incurable and the patient is at risk of a bad outcome. It is therefore essential for both patients and their physicians** to know they are on a better therapy than tamoxifen to prevent the disease returning.

The impact of treatment on quality of life is also an important consideration in early breast cancer, and data have shown that the clinical benefits of anastrozole are achieved without adversely affecting the quality of patients' lives.(5)

"The ATAC 100-month data confirm that anastrozole is now the gold standard treatment for post-menopausal women with hormone-sensitive early breast cancer, irrespective of the
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SOURCE AstraZeneca
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