Navigation Links
Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
Date:5/31/2008

two years(1).

The primary endpoint of the study was disease-free survival for all four study groups. Recurrence-free survival, overall survival, and safety were secondary endpoints. (Disease-free survival was defined as the length of time after randomization during which patients had no local recurrence, contralateral breast cancer, distant metastasis, secondary carcinoma, and/or death from any cause. Recurrence-free survival was defined as the length of time after randomization during which patients had no local recurrence, contralateral breast cancer, distant metastasis, and/or secondary carcinoma.) Exploratory endpoints included bone-metastases-free survival(1).

At the median follow-up of five years, disease-free survival events were reduced by 36% (P=0.01) with Zometa and the risk of recurrence-free survival events fell by 35% (P=0.015) versus hormone therapy alone. Sixteen deaths had occurred among patients who received Zometa with hormone therapy versus 26 deaths in patients who received hormone therapy alone, which resulted in a nonsignificant reduction in the risk of death in patients who received Zometa compared with those who received hormone therapy alone (P=0.103). A similar trend was noted toward a reduction in bone metastases among patients who received Zometa compared with those who received hormone therapy alone (16 versus 23). Longer follow-up and a larger number of events will be necessary to determine if any significant differences exist between the groups for overall survival and bone-metastases-free survival. Overall, treatment was generally well-tolerated and side effects were consistent with known drug safety profile(1).

About Zometa

Zometa is indicated for patients with multiple myeloma and documented bone metastases from solid tumors in conjunction with standard antineoplastic therapy; prostate cancer should have progressed after treatment with at least one hormonal therapy.

Important Safety Information '/>"/>

SOURCE Novartis
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
2. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
3. Video: New Results From One of the Worlds Largest Breast Cancer Trials Herald Hope for Thousands of Women
4. Video: Quest Diagnostics Health Trends(TM) Report Shows Significant Gap in Care for Patients With Chronic Kidney Disease
5. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
6. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
7. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
8. Video: New Research Discovers Independent Brain Networks Control Human Walking
9. BioElectronics Announces Major Clinical Trials
10. XIENCE(TM) V Drug Eluting Stent from Abbott Outperforms Market-Leading Stent in Reducing Major Adverse Cardiac Events at Two Years
11. New Data on SEROQUEL XR(TM) in Treatment of Both Major Depressive Disorder and Generalized Anxiety Disorder Presented at APA Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2015)...  DURECT Corporation (Nasdaq: DRRX ) announced today ... revenues were $4.8 million and net loss was $4.9 ... as compared to total revenues of $6.3 million and ... ended March 31, 2014.At March 31, 2015, we had ... and investments of $34.9 million at December 31, 2014.  ...
(Date:4/30/2015)... -- Pharmacists at Osco Drug have voted to become members ... . The newly organized group consists of 20 pharmacists ... throughout Maine . "We ... them the powerful representation that Teamsters Local 340 can bring ... Local 340. "We will work tirelessly, providing them with the ...
(Date:4/30/2015)... , April 30, 2015  Isis Pharmaceuticals, Inc. ... earned a $10 million milestone payment from Biogen ... to treat a neurological disorder.  This is the ... in development, under Isis, and Biogen,s broad strategic ... treat neurological and neuromuscular disorders.  ...
Breaking Medicine Technology:DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 2DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 3DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 4DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 5DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 6DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 7DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 8DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 9Isis Pharmaceuticals Earns $10 Million Milestone Payment From Biogen 2Isis Pharmaceuticals Earns $10 Million Milestone Payment From Biogen 3
(Date:5/2/2015)... 02, 2015 On Tuesday April 7th, ... (ELCH) gathered to celebrate improvements in patient care. In ... Partners (RVHP), had zero acquired ventilator associated infections, zero ... infections. ELCH was also recently named a Top Performer ... at ELCH credited the teamwork of staff from all ...
(Date:5/2/2015)... ZoomCare, the Portland-based innovator of on-demand healthcare ... its new healthcare insurance to individuals and small businesses ... System is the nation’s first health insurance system built ... Personal Health Insurance was ZoomCare’s first such filing including ... to review and regulation by the Oregon Insurance Division. ...
(Date:5/1/2015)... Caicos Islands, BWI (PRWEB) May 02, 2015 ... website! It is http://www.thevenetiangracebay.com , and it ... it incorporates the stunning white and attractive turquoise hues ... study of Google, sixty seven percent of leisure travelers ... study showed that smartphones were used in the planning ...
(Date:5/1/2015)... 01, 2015 Royal River Natural Foods, ... reports on a new study that found two natural ... and improved physical function as well as standard drug ... of the knee. , The report is part of ... Well Being® ,” which Royal River Natural Foods publishes ...
(Date:5/1/2015)... DC (PRWEB) May 01, 2015 It’s raining ... and House introducing proposals to expand federal support for telemedicine. ... years that ATA has been working with Congress,” said Jonathan ... actions signify how the nation is poised to embrace the ... is one more step in fulfilling ATA’s mission to improve ...
Breaking Medicine News(10 mins):Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2Health News:ZoomCare Applies to be on Oregon Exchange 2Health News:Turks and Caicos Resort, The Venetian on Grace Bay, Launches New Web Presence 2Health News:New Study Finds Nutrients Ease Arthritis Pain, Retailer Reports 2Health News:ATA: Congress Floods the Halls with Telemedicine Proposals 2
... (Nasdaq: ALTH ) today announced the appointment ... this position, Mr. Bennett,will lead the Company,s manufacturing ... of Allos, product candidates., "We are delighted ... Berns,President and CEO. "Bruce,s experience in all aspects ...
... Jan. 28 In a reversal of what has,become ... online interactive training coupled with two hours of live ... all EZM Web,customers., EZM Web tracks and controls ... vehicle plus inventory control via the Web. It is ...
... (NYSE: NTY ), (http://www.NBTY.com ), a leading global ... the fiscal first quarter ended,December 31, 2007., For ... sales were,$511 million compared to $506 million for the ... $5 million or 1%., Net income for the ...
... Advocates for Women,s Health and Rights call for an ... Government Funding for Failed Abstinence-Only Programs, NEW ... Sexuality Information and Education Council of the United States,(SIECUS) ... will hold,panel discussions at Bowdoin College (January 29) and ...
... Shazaaam! LLC, an integrated,marketing communications agency headquartered ... and Marketing Communications Agency of,Record for Enuresis ... social marketing, proactive and reactive,blogging, traditional and ... and visibility among its target market., ...
... of caffeine in coffee, tea or soft drinks increases ... and may undermine efforts to control their disease, say ... new technology that measured participants glucose (sugar) levels on ... a psychologist at Duke and the lead author of ...
Cached Medicine News:Health News:Allos Therapeutics Appoints Bruce K. Bennett as Vice President, Manufacturing 2Health News:Allos Therapeutics Appoints Bruce K. Bennett as Vice President, Manufacturing 3Health News:Maintenance Software Company Bucks Trend, Offers Unlimited No-Charge Product Tech Support 2Health News:NBTY Reports First Quarter Results 2Health News:NBTY Reports First Quarter Results 3Health News:NBTY Reports First Quarter Results 4Health News:NBTY Reports First Quarter Results 5Health News:NBTY Reports First Quarter Results 6Health News:NBTY Reports First Quarter Results 7Health News:NBTY Reports First Quarter Results 8Health News:NBTY Reports First Quarter Results 9Health News:NBTY Reports First Quarter Results 10Health News:NBTY Reports First Quarter Results 11Health News:NBTY Reports First Quarter Results 12Health News:NBTY Reports First Quarter Results 13Health News:NBTY Reports First Quarter Results 14Health News:Harm of Abstinence-Only Programs in U.S. and Abroad Subject of Panel Discussion at Two Maine College Campuses 2Health News:Harm of Abstinence-Only Programs in U.S. and Abroad Subject of Panel Discussion at Two Maine College Campuses 3Health News:Shazaaam! Named PR Agency of Record for Enuresis Treatment Center 2Health News:Cutting caffeine may help control diabetes 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: