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Video: MADIT-CRT Trial Results Provide Clinical Evidence That Cardiac Resynchronization Therapy Significantly Slows Heart Failure Progression
Date:9/1/2009

NATICK, Mass., and BARCELONA, Spain, Sept. 1 /PRNewswire/ -- Boston Scientific Corporation (NYSE: BSX) today announced final results from the landmark MADIT-CRT trial, which were published by the New England Journal of Medicine and presented during a Hot Line session at the annual European Society of Cardiology (ESC) Congress in Barcelona.

To view the Multimedia News Release, go to: http://www.prnewswire.com/mnr/bostonscientific/36500/

(Photo: http://www.newscom.com/cgi-bin/prnh/20090901/NY68733 )

Arthur Moss, M.D., Professor of Medicine at the University of Rochester Medical Center and Principal Investigator of the trial, presented the MADIT-CRT data. The primary endpoint showed that Boston Scientific's cardiac resynchronization therapy defibrillators (CRT-Ds) were associated with a 34 percent relative reduction in the risk of all-cause mortality or first heart failure event in asymptomatic and mild (NYHA Class I and II(1)) heart failure patients, when compared to standard implantable cardioverter defibrillators (ICDs) (p=0.001).

In addition, MADIT-CRT data showed that:

  • CRT-D therapy reduces the relative risk of heart failure events by 41 percent when compared to ICD therapy (p< 0.001).
  • Patients treated with CRT-D therapy showed an improvement of 11 percent in Left Ventricular Ejection Fraction(2) after one year, compared to a three percent improvement for ICD patients.

"The MADIT-CRT Executive Committee anticipated that the benefit for the CRT-D
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SOURCE Boston Scientific Corporation
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