Navigation Links
Video: Femara(R) First Aromatase Inhibitor to Indicate Survival Benefit Versus Tamoxifen When Taken for Five Years After Breast Cancer Surgery
Date:12/11/2008

sented these results from the BIG 1-98 trial today at the 31st Annual CTRC-AACR San Antonio Breast Cancer Symposium (SABCS), an international scientific symposium for scientists and clinicians in breast cancer.

"These data represent an important milestone in the treatment of women with breast cancer. For the first time, we are seeing suggested survival benefit with aromatase inhibitor therapy for five years compared with tamoxifen for the same time period," said Henning T. Mouridsen, MD, PhD, Professor of Oncology, Copenhagen University Hospital and one of the investigators of the BIG 1-98 trial. "The potential reduction in the risk of death that we are seeing with letrozole in the adjuvant setting may be a positive result of letrozole's early and sustained reduction in the risk of recurrence and distant metastases."

BIG 1-98 is the only clinical trial designed to explore both a head-to-head comparison of an aromatase inhibitor with tamoxifen during the first five years following breast cancer surgery and the sequencing of both agents to determine the most effective approach to minimizing the risk of recurrence. In the initial adjuvant setting, Femara is the only aromatase inhibitor to have demonstrated an early significant reduction in distant metastases versus tamoxifen, at a median duration of follow-up of 26 months.

Beyond the potential survival benefit of 13% (P=0.08, HR=0.87, 95% CI: 0.75-1.02) reduction in risk of death for Femara patients seen in the ITT analysis, Femara demonstrated significant long-term benefit in reducing the risk of disease-free survival events by 12% (P=0.03, HR=0.88, 95% CI: 0.78-0.99) and reducing the risk of distant metastases by 15% (P=0.05, HR=0.85, 95% CI: 0.72-1.00) compared with tamoxifen.

"Femara has consistently demonstrated remarkable results and these data reaffirm the benefit of Femara for postmenopausal women with early-stage bre
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia
2. Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Dont Get Their Families Vaccinated
3. Video: Novartis Vaccines and PTA Battle Flu: Public Health Vaccination Initiative Urges Families Lets Fight Flu Together!
4. Video: Answer to Curing a Failing Heart May Exist in Bodys Own Do-It-Yourself Repair Kit
5. Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain
6. Video: The Looming Crisis in Cancer Drug Development: 97% of Adult Cancer Patients Do Not Take Advantage of Clinical Trial Programs
7. Video: Large, Multi-Center Trial Demonstrates Comparable Accuracy for Virtual Colonoscopy and Standard Colonoscopy
8. Video: Prognosis Split for Hip Fracture and Hip Replacement in the Elderly
9. Video: Resveratrol-based Nutriceutical (Longevinex(R)) Induces Favorable Changes on Gene Expression in Mouse Heart At Doses 17-320 Times Lower Than Prior Studies
10. Video: Sanford Healths Journey to Cure Type 1 Diabetes Receives Major Boost
11. Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/6/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/rvhg65/european_patient ) has ... Equipment Market by Product, by Type of Care, by ... report to their offering. The European ... a double-digit CAGR of 11.4% to reach $5,150.2 million ... geriatric population, increasing incidences of lifestyle diseases, and high ...
(Date:3/5/2015)... DETROIT , March 5, 2015   ... percent and met all seven optional leading indicators ... Benefit Management. "We are very proud ... said Rene Acker , Chief Operating Officer ... employees, dedication and commitment to transparency, flexibility and ...
(Date:3/5/2015)... March 5, 2015 Vermillion, Inc. (Nasdaq: ... focused on gynecologic disease, announced today it will ... the market open on Wednesday, March 25, 2015, ... at 8:30am Eastern. Conference Call & Webcast: ... Eastern/5:30am Pacific Domestic: , 800-753-9057International: , 913-981-5571Conference ID: ...
Breaking Medicine Technology:European Patient Handling Equipment (Wheelchair, Scooters, Bathroom Safety Supply, Mechanical, Ambulatory) Market 2015-2019 2European Patient Handling Equipment (Wheelchair, Scooters, Bathroom Safety Supply, Mechanical, Ambulatory) Market 2015-2019 3MeridianRx Earns Highest URAC Accreditation Status 2Vermillion to Report Fourth Quarter and Year-End 2014 Financial Results and Host an Investor Conference Call on March 25 2
(Date:3/6/2015)... York, New York (PRWEB) March 06, 2015 ... dancing’s dazzling days on the grand stage, to the silver ... Dancers sparkle throughout with precision toe-tapping numbers and their famous ... Karyn Tomczak deliver the rich history of tap dancing in ... forms to come out of the United States. , ...
(Date:3/6/2015)... 06, 2015 At Natural Products ... today the launch of its powerful, location-aware iOS ... and sustainable products at any retailer that carries ... at Expo West Booth 6054. , Makeena’s ... Kosher, non-GMO, organic, Paleo, and vegan, among many ...
(Date:3/6/2015)... First Choice Emergency Room opened its ... located at 13351 W. Bowles Avenue, Littleton, Colorado and is ... 24-7 to provide the highest quality emergency medical care to ... First Choice Emergency Room Littleton. , First Choice ... Denver Chamber of Commerce and a medical community open house ...
(Date:3/6/2015)... 06, 2015 Truly Nolen, the largest ... announce the grand opening of their first independently-owned and ... down to the Fort Mill – Rock Hill, SC ... 27th, 2015 at their new location. , ... of collective experience in the pest control industry. Locally ...
(Date:3/6/2015)... The Gluten-Free Certification Program (GFCP), ... pleased to announce that Dufflet Pastries, the ground-breaking ... their product line of gluten-free treats certified by ... as satisfying as any of their other desserts! ... contains hydrogenated fats or oils, artificial flavours, colours ...
Breaking Medicine News(10 mins):Health News:The Legacy Dancers, a Dazzling Dance Troupe of Former Rockettes, Kick to New Heights in “On Tap: From Broadway to the Silver Screen” 2Health News:Makeena Launches App that Makes Healthy and Sustainable Products More Affordable for Shoppers 2Health News:Makeena Launches App that Makes Healthy and Sustainable Products More Affordable for Shoppers 3Health News:First Choice Emergency Room Opens New Facility in Littleton, Colorado 2Health News:First Truly Nolen Franchise Opening in North Carolina 2Health News:Dufflet Pastries® Impressive Collection of Brownies, Cakes, Pies and Cakelets® Now Includes a Gluten-Free Line Certified By the GFCP. 2Health News:Dufflet Pastries® Impressive Collection of Brownies, Cakes, Pies and Cakelets® Now Includes a Gluten-Free Line Certified By the GFCP. 3Health News:Dufflet Pastries® Impressive Collection of Brownies, Cakes, Pies and Cakelets® Now Includes a Gluten-Free Line Certified By the GFCP. 4
... research team led by Queen,s University have developed a ... new drug will benefit sufferers who have the ,Celtic ... Ireland. The study, which was carried out by ... the Belfast Health and Social Care Trust and teams ...
... LOS ANGELES(June 20, 2011)Doctors warned of a potential public health ... and New York who developed serious skin reactions after smoking ... medication drug dealers are using to dilute, or "cut," up ... report, published online in the Journal of the American ...
... Although sex and infidelity are now only a keyboard ... no substitute for physical, face-to-face contact in our sexual ... Kholos Wysocki, from the University of Nebraska at Kearney, ... They investigated the behaviors of infidelity on the internet ...
... as lesbian, gay, or bisexual increases emotional well-being even ... benefits of revealing one,s sexual identity -- less anger, ... supportive settings, shows a study published June 20 in ... findings underscore the importance of creating workplaces and other ...
... SUNDAY, June 19 (HealthDay News) -- Dads don,t have to forego ... research that has linked red and processed meat consumption to ... M.D. Anderson Cancer Center say that small changes in what people ... toward lowering their risk of cancer. , , "The good news ...
... An international research team, co-led by scientists at ... potential susceptibility genes for development of progressive supranuclear ... symptoms similar to those of Parkinson,s disease ... being published online June 19 in Nature Genetics ...
Cached Medicine News:Health News:Scientists develop first ever drug to treat 'Celtic gene' in cystic fibrosis sufferers 2Health News:Adulterated cocaine causing serious skin reactions 2Health News:Let your fingers do the talking: Sexting and infidelity in cyberspace 2Health News:Is coming out always a good thing? 2Health News:Is coming out always a good thing? 3Health News:Dads Can Light Their Grills Without Fear 2Health News:Possible susceptibility genes found in neurodegenerative disorder 2Health News:Possible susceptibility genes found in neurodegenerative disorder 3
Arthrex has the most extensive offering of arthroscopic suture passing instruments,available anywhere in the world. We have speci? cally designed the function of our,instruments to work hand in hand ...
Arthrex has the most extensive offering of arthroscopic suture passing instruments,available anywhere in the world. We have speci? cally designed the function of our,instruments to work hand in hand ...
Arthrex has the most extensive offering of arthroscopic suture passing instruments,available anywhere in the world. We have speci? cally designed the function of our,instruments to work hand in hand ...
45 left angled suture passer....
Medicine Products: