Navigation Links
Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
Date:6/10/2008

gram for liraglutide.

The double-blinded, double-dummy, randomized, parallel group, actively-controlled, multicenter, multinational 52-week trial compared the efficacy and safety of two doses of liraglutide (1.2 and 1.8 mg once daily) to glimepiride (8 mg once daily) in patients with type 2 diabetes treated with diet/exercise or not more than half the maximum dose of one OAD for greater than or equal to two months. Patients treated with diet and exercise had HbA1c between 7.0% and 11.0%. Patients previously treated with oral monotherapy had an HbA1c between 7.0% and 10.0%.

The data showed that at both doses tested, liraglutide provided substantial improvement in glucose control from baseline and statistically significantly better glucose control than glimepiride. Patients previously treated with diet and exercise had greater decreases in HbA1c, as compared to subjects switched from an OAD to liraglutide.

In addition, there was significant weight loss, as compared to weight gain with glimepiride, and significantly greater reduction in systolic blood pressure with both liraglutide groups compared to glimepiride.

Results of a 52-week trial of liraglutide monotherapy in patients with inadequate glucose control from previous diet and exercise or treatment with one OAD:

Monotherapy

Liraglutide Liraglutide Glimepiride

1.8 mg 1.2 mg

N 246 251 248

HbA1c (%) (Mean)

Baseline 8.2 8.2 8.2

Change from baseline -1.14 -0.84 -0.51

Previous diet/exercise-

treated patients -1.60 -1.19 -0.88

Previous OAD-treated

patients -0.71 -0.47 -0.17

Patients (%)

achieving HbA1C <7%

All patients 50.9
'/>"/>

SOURCE Novo Nordisk
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Video: New Research Discovers Independent Brain Networks Control Human Walking
2. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
3. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
4. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
5. Video: Quest Diagnostics Health Trends(TM) Report Shows Significant Gap in Care for Patients With Chronic Kidney Disease
6. Video: New Results From One of the Worlds Largest Breast Cancer Trials Herald Hope for Thousands of Women
7. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
8. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
9. Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
10. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
11. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 11, 2014 According to a ... Devices Market (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) ... Forecast, 2013-2019" the global endoscopy devices market was valued ... to grow at a CAGR of 6.8% from 2013 ... 36.9 billion in 2019. Browse the full ...
(Date:7/11/2014)... , July 11, 2014 ... to Safety & Health Expo 2014 were ... move to London , ... attending exhibition.          ... http://photos.prnewswire.com/prnh/20140711/696892-a )      (Photo: ...
(Date:7/10/2014)... , 11. Juli 2014 /PRNewswire/ ... Kameras für die molekulare Bildgebung, einschließlich ... heute die CE-Zulassung für sein Navigator ... kann Dilon das Produkt jetzt europaweit ... den Großteil der europäischen Länder ausgedehnt ...
Breaking Medicine Technology:Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2
... Nov. 21 An urgent need for new medicines ... has prompted a growing number of collaborations among academic ... biotechnology companies. As noted today in a symposium at ... Tropical Medicine and Hygiene (ASTMH), these collaborations are opening ...
... , LARGO, Fla., Nov. 20 Unilens ... UVI), which develops, licenses, manufactures, distributes and markets specialty ... first quarter ended September 30, 2009 (FY2010). , Net ... first quarter, 4.4% less then $1,761,526 reported in the ...
Cached Medicine Technology:ASTMH Symposium Showcases Efforts To Meet the Need for New Medicines to Treat Infectious Diseases in Developing Countries 2ASTMH Symposium Showcases Efforts To Meet the Need for New Medicines to Treat Infectious Diseases in Developing Countries 3Unilens Vision Reports Record First Quarter Earnings and Royalty Income 2Unilens Vision Reports Record First Quarter Earnings and Royalty Income 3Unilens Vision Reports Record First Quarter Earnings and Royalty Income 4
(Date:7/11/2014)... Utilizing the Keller Funnel, Quatela Center ... topped a record number of complication-free breast augmentations. ... successful procedures without the occurrence of a capsular contraction. ... the country for his expertise with the breast augmentation ... the foundation for numerous studies and research. Most ...
(Date:7/11/2014)... -- U.S. health officials have concluded that it,s highly ... during a safety mishap last month. But, the ... announced a moratorium on the transfer of any dangerous ... a report issued Friday, the CDC outlined several measures ... incident doesn,t occur again. Last month, as many as ...
(Date:7/11/2014)... According to a new market research ... Communication Technology (ZigBee, Z-Wave, Bluetooth, Wi-Fi, NFC, RFID), Application ... Transportation, Agriculture) & Geography - Global Trends & Forecasts ... Things market was worth $1029.5 Billion in 2013, and ... an estimated CAGR of 4.08% from 2014 to 2020. ...
(Date:7/11/2014)... As reported by the New ... a significant number of severe adverse events such as ... even death from the highly-promoted and costly immune-system drug, ... report , a regulatory filing revealed that the ... was almost 14% of prescriptions, up from 9.1% in ...
(Date:7/11/2014)... The Corn Farming industry experienced ... the heels of fresh biofuel demand. The Federal Renewable ... larger share of their farmland to cultivating high-value corn ... the mixing of 5.0% renewable content in gasoline across ... States created a key export market for Canadian corn, ...
Breaking Medicine News(10 mins):Health News:Rochester Surgeon Hits Milestone with Keller Funnel 2Health News:CDC Issues Tough Report on Anthrax Scare 2Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Acthar’s Deadly Adverse Events Revealed 2Health News:Acthar’s Deadly Adverse Events Revealed 3Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 2Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 3
... ... for a blue parking placard utilized by persons with permanent disabilities violated federal law. On ... meet to discuss reimbursement to Class Members. To qualify for reimbursement, a valid claim form ... Austin, TX (PRWEB) ...
... , ... America , WASHINGTON , Jan. 16 ... Haiti relief efforts using a new Portuguese website called ... American States announced. , AjudaPanamericana.org is the third language option offered ...
... ... ... to the disastrous earthquake in Haiti, the State of California has asked Scripps Health to ... (SMRT) for deployment to Haiti with one of the state’s mobile field hospitals. The ...
... prostatectomy, obese whites have worse outcomes, study finds , ... may affect the outcome of men with diabetes who ... , "We found that diabetes was significantly associated with ... aggressive disease for all other subsets of men in ...
... OAKLAND, Calif. , Jan. 15 Kaiser ... four national disaster relief organizations to provide aid to ...  The nonprofit health care organization has wired the funding to ... and is providing expertise and support to U.S. disaster response ...
... , NASHVILLE, Tenn. , ... it has committed to match employee contributions and provide in-kind ... donations will go to relief organizations including the Red Cross ... , Relief agencies are advising that cash and supplies are ...
Cached Medicine News:Health News:$20,200,816.17 Settlement Fund Proposed for Blue Parking Placard Litigation to be Divided Among Class Members Who Submit a Valid Claim Form. 2Health News:Haiti Relief Site Now in Portuguese 2Health News:Haiti Relief Site Now in Portuguese 3Health News:Scripps Health Preparing for Deployment of Medical Response Team to Haiti, 2Health News:Scripps Health Preparing for Deployment of Medical Response Team to Haiti, 3Health News:Scripps Health Preparing for Deployment of Medical Response Team to Haiti, 4Health News:Race, Weight May Influence Success of Prostate Surgery 2Health News:Kaiser Permanente Donates $500,000 for Relief Efforts Following Earthquake in Haiti 2Health News:Kaiser Permanente Donates $500,000 for Relief Efforts Following Earthquake in Haiti 3Health News:HCA Pledges $1 Million in Cash and Supplies to Haiti Relief Effort 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: