Navigation Links
Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
Date:8/19/2007

Administration (FDA) to include these data in the prescribing information in the U.S.

Pharmion is also developing a next generation product, oral Azacitidine, for the treatment of MDS and other cancers where demethylation can provide an anti-tumor effect. Oral Azacitidine is the subject of a Phase 1 multi-center, open label dose escalation trial that will assess the maximum tolerated dose, dose limiting toxicities and safety of a seven day, multi-cycle oral dosing regimen of oral Azacitidine in patients with MDS and AML. In addition, the trial will examine pharmacokinetics and pharmacodynamic effects of orally administered Azacitidine, as compared with parenteral Vidaza.

Pharmion will hold a conference call to discuss these results later this morning, August 2, at 9:00 a.m. ET. The conference call will be simultaneously webcast on the Company's web site at http://www.pharmion.com, and archived for future review. Dial-in numbers for the conference call for institutional investors and analysts are as follows: participants from the U.S. 866.314.5232, International participants 617.213.8052, passcode: 71992680.

About the Trial Design

This was the largest randomized study ever conducted in higher-risk MDS. The study was a multi-center, randomized, open-label, parallel-group, Phase 3 trial of subcutaneous (SC) Vidaza (administered at 75/mg/m2/day SC for seven consecutive days every 28 days) plus best supportive care versus CCR plus best supportive care for the treatment of MDS. CCR consisted of one of three physician selected regimens: best supportive care alone, low-dose cytarabine plus best supportive care or standard chemotherapy plus best supportive care. EPO and prophylactic G-CSF use was not permitted. The CCR represented standard of care within the territories where the trial was conducted. The study evaluated 358 higher-risk MDS patients at sites in the U.S., Europe and Australia. Patients
'/>"/>

SOURCE Pharmion Corporation

Copyright©2007 PR Newswire.

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Clinical Data Reported on Vidaza in Hematologic Malignancies and Advanced Solid Tumors
2. Liraglutide provides significantly better glucose control than insulin glargine in phase 3 study
3. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
4. Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
5. Lumiracoxib Study Showed Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
6. Actemra (tocilizumab) Significantly Improves Symptoms of Rheumatoid Arthritis Compared to a Current Standard of Care
7. Next Safety, Inc.s Innovative Drug Delivery System Will Replace Cigarettes and Significantly Advance Pulmonary Medication Delivery
8. Ivivis PEMF Technology Significantly Improves Neuron Survival in Parkinsons Disease Model, Study Finds
9. Mercks Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study
10. The Eloxatin-Based Regimen (FOLFOX4) Significantly Improved Progression Free Survival When Given Before and After Surgery in Patients With Resectable Liver Metastases From Colorectal Cancer
11. Nexavar Significantly Extends Overall Survival by 44% in Liver Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... , September 17, 2014 According ... by Component (Sensor, Battery, Memory Device, Display, & Microprocessor/MCU), ... & Wellness), and by Geography - Global Forecast to ... electronics market is expected to reach $56.50 Billion by ... to 2020. Browse 235 market data Tables ...
(Date:9/17/2014)... -- Women everywhere know how frustrating a vaginal infection ... often also embarrassing and have a way of derailing ... http://ph-defense.com ) is a new, over-the-counter product designed to ... Odor, discharge, and discomfort or itch ... many cases, the cause of such problems can be ...
(Date:9/17/2014)... LEIPZIG, Germany , Sept. 17, ... has entered into an exclusive technology development partnership ... imaging agents to image CD4+ positive immune T ... ImaginAb,s capability to precisely diagnose and determine therapeutic ... areas. The ability to image CD4+ T-cells will ...
Breaking Medicine Technology:Medical Electronics Market Worth $56.50 Billion by 2020 2Medical Electronics Market Worth $56.50 Billion by 2020 3Medical Electronics Market Worth $56.50 Billion by 2020 4New Product from Vireo Systems: pH-D Feminine Health Support 2ImaginAb Expands ImmunoPET Pipeline to Include CD4+ T-Cell Imaging 2
... , , , ... service Contract Research Organization (CRO) founded in India, today announced the ... Application Suite (OLSAS) by going live with Oracle Siebel Clinical Trial ... , "We are excited to have the rollout of ...
... Aug. 5 /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: DDS; NASDAQ: ... a New Drug Submission (NDS) with the Therapeutic Products ... the antidepressant trazodone. , "We are pleased to file ... R. Howard-Tripp, President and Chief Executive Officer, Labopharm Inc. ...
Cached Medicine Technology:SIRO Clinpharm Completes Successful Implementation of Oracle Life Sciences Application Suite 2Labopharm files New Drug Submission with Health Canada for novel antidepressant 2Labopharm files New Drug Submission with Health Canada for novel antidepressant 3
(Date:9/17/2014)... Recently, UWDress.com, an innovative company that provides many kinds ... released its 2014 empire waist evening dress ... big sale for these new and beautiful products. All ... from 15 to 65 percent off. , It ... to wear materials. Its elegant items include gold empire ...
(Date:9/17/2014)... 2014 According to Centers for ... an estimated 173,285 sports- and recreation-related traumatic brain injuries, ... a blood test may be available to help doctors ... recovery will take. , In March of this ... found a way to test blood for a protein ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 According ... Drug Administration report titled “Adverse Events Associated with ... a Dermal Filler,” unapproved use of Expression, a ... resulted in adverse reactions including discoloration, lumps, bruising, ... with FDA approval for cosmetic use include ...
(Date:9/17/2014)... Final Cut Pro X plugin developers have ... Pixel Film Studios. , “ProBlue 5k is a compilation of ... to epic,” said Christina Austin, CEO of Pixel Film Studios. ... a definite game changer.” , ProBlue 5k is the ultimate ... filmmaker ! This footage compilation of over 100 anamorphic flares ...
(Date:9/17/2014)... struggle to distinguish between a business strategy and business plan, ... answer by reading Per Wickstrom’s latest blog post. , “The ... and a business strategy are both strategic – and what’s ... view it is that a business plan is part one, ... , According to the blog post, a business plan is ...
Breaking Medicine News(10 mins):Health News:2014 Empire Waist Evening Dress Collection Now Unveiled At UWDress.com 2Health News:Breakthrough blood test will improve concussion diagnoses, treatment 2Health News:Breakthrough blood test will improve concussion diagnoses, treatment 3Health News:Simon Ourian, Kim Kardashian's Cosmetic Surgeon, Warns About Illegal Use of Expression as a Dermal Filler 2Health News:A New Plugin Entitled ProBlue 5k Was Released Today from Pixel Film Studios Exclusively for Final Cut Pro X 2Health News:Per Wickstrom’s Latest Blog Explores the Difference Between a Business Plan and a Business Strategy 2
... the Eye ... Americans at Great Risk, PINELLAS PARK, Fla., Nov. 12 ... largely unaware of,the dangers that extended exposure to harmful ultraviolet (UV) ... England Eye Institute,and Transitions Optical, found that while nearly 80 percent ...
... November 12 Schlafender Hase GmbH,today released the ... The Text Verification Tool is a patent-protected ... print layout ("artwork") on the data,level - independent ... may be annotated, saved in PDF format and ...
... with prostate cancer are at greater risk of death after ... 2007 issue of CANCER, a peer-reviewed journal of the American ... Massachusetts General Hospital in Boston and colleagues, found that a ... diagnosis was an independent risk factor for prostate cancer-related death. ...
... We Are" (p. 42). "There was at,the end of 1968 ... For the Sixties were also the glory years of the ... writes former,NBC News anchor Tom Brokaw, in his forthcoming book, ... which Newsweek looks back at,one of the defining years of ...
... in Washington D.C., North Texas, Los Angeles, and ... Chicago, Effort latest in long K of C tradition ... ... distributed a total of $1 million worth of wheelchairs to veterans,in need at four locations on ...
... of the same,family, who owned and operated a ... Comprehensive Outpatient Rehabilitation Facilities have,each been sentenced to ... General Alice S. Fisher of the Criminal Division ... District of Florida announced today., Carlos Berenguer, ...
Cached Medicine News:Health News:Survey Confirms Americans Have a True 'Blind Spot' Regarding Their Eye Health - and the Real Danger of UV Rays 2Health News:Survey Confirms Americans Have a True 'Blind Spot' Regarding Their Eye Health - and the Real Danger of UV Rays 3Health News:Survey Confirms Americans Have a True 'Blind Spot' Regarding Their Eye Health - and the Real Danger of UV Rays 4Health News:Schlafender Hase Releases Text Verification Tool 4.0 2Health News:Obesity and overweight linked to higher prostate cancer mortality 2Health News:NEWSWEEK: Media Lead Sheet/November 19, 2007 Issue (on newsstands Monday, November 12) 2Health News:NEWSWEEK: Media Lead Sheet/November 19, 2007 Issue (on newsstands Monday, November 12) 3Health News:NEWSWEEK: Media Lead Sheet/November 19, 2007 Issue (on newsstands Monday, November 12) 4Health News:NEWSWEEK: Media Lead Sheet/November 19, 2007 Issue (on newsstands Monday, November 12) 5Health News:Knights Distribute $1 Million Worth of Wheelchairs to Veterans 2Health News:Four Miami Health Care Company Owners Sentenced to 57 Months in Prison For Medicare Fraud 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: