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Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial
Date:11/12/2008

nt of the CMV vaccine; whether the CMV vaccine will achieve the safety and efficacy endpoints in the Phase 2 trial; whether T-cell responses will control CMV reactivation and disease; whether the interim evaluation of immunogenicity in the Phase 2 trial will be predictive of clinical benefit, and if so, whether such benefit will be confirmed with clinical efficacy results in the second quarter of 2009, if at all; whether the company will expand development of a CMV vaccine to address prevention of congenital disease, and if so, whether such results will be successful; whether Vical or its collaborative partners will seek or gain approval to market any product candidates; whether Vical or its collaborative partners will succeed in marketing any product candidates; and additional risks set forth in the company's filings with the Securities and Exchange Commission. These forward-looking statements represent the company's judgment as of the date of this release. The company disclaims, however, any intent or obligation to update these forward-looking statements.

(1) Avetisyan G, et al. Impact on the cytomegalovirus (CMV) viral load by CMV-specific T-cell immunity in recipients of allogeneic stem cell transplantation. Bone Marrow Transplant. 2006 Nov;38(10):687-92.

Avetisyan G, et al. Evaluation of intervention strategy based on CMV-specific immune responses after allogeneic SCT. Bone Marrow Transplant. 2007 Nov;40(9):865-9.

Contact: Alan R. Engbring

(858) 646-1127

Website: http://www.vical.com


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