Navigation Links
Versatility of 454 Sequencing(TM) Demonstrated in Three Publications in Science Last Week
Date:10/2/2007

and care for their siblings is a defining feature of eusociality and a major challenge for evolutionary theory. In the study, "Wasp Brain Gene Expression Supports an Evolutionary Link between Maternal Behavior and Eusociality," researchers used 454 Sequencing to examine messenger RNA from the brains of wasps and correlate different expression patterns to different social behaviors. Insulin-related genes were among those genes showing a distinct pattern, suggesting that the evolution of eusociality involved major nutritional and reproductive pathways.

The study entitled "Whole-Genome Shotgun Sequencing of Mitochondria from Ancient Hair Shafts" combines a novel approach of preparing ancient DNA with 454 Sequencing to quickly and affordably sequencing the complete mitochondria from 10 individual mammoths. To put this new study in perspective, only seven mitochondrial genomes from extinct animals had been previously published, four from ancient birds, two mammoths and one of the mastodon, a distant relative of mammoths. The method for obtaining ancient DNA, as described in today's paper, uses hair shafts and not live cells. Hair from many extinct species is available in museum collections around the world. The new protocol, along with 454 Sequencing, opens the door to sequence many ancient species.

"Three diverse publications appearing in Science the same week and utilizing 454 Sequencing is a testament to the system's flexibility and applicability to life science research," explained Michael Egholm, Ph.D., vice president of research and development at 454 Life Sciences. "Researchers were able to sequence ancient and degraded DNA, obtain a paired-end map of structural variation throughput the human genome at unprecedented resolution, and analyze the role of gene expression in the evolution of eusociality. All of this in one week in Science is very inspirational."

454 Life Sciences develops and commercializes the innovative Genome Sequencer(TM) system f
'/>"/>

SOURCE 454 Life Sciences
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Study Shows Ixabepilone Demonstrated Clear Activity in Patients with Metastatic Breast Cancer Resistant to Anthracycline, Taxane, and Capecitabine
2. Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone
3. Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone
4. Investigational Study Demonstrated a Re-Establishment of Clinical Improvement with Orencia (Abatacept) in Children with Juvenile Idiopathic Arthritis upon Re-Introduction of Therapy
5. Study Demonstrated Rozerem (ramelteon) Does Not Affect Middle-of-the-Night Balance in Older Adults with Insomnia
6. Repros Reports That Proellex Has Demonstrated Superior Efficacy and Safety in Endometriosis When Compared to Standard of Drug Care
7. Organons Sugammadex Demonstrated a 9-12 Times Faster Recovery in Phase III Pivotal Trial as Compared to Neostigmine
8. Organons Sugammadex Demonstrated a 9-12 Times Faster Recovery in Phase III Pivotal Trial Compared to Neostigmine
9. Trexima (Sumatriptan/Naproxen Sodium) Demonstrated Migraine-Free Response Across Multiple Attacks
10. Data Demonstrated Metastatic Melanoma Response to Investigational Immunotherapy Ipilimumab
11. Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... PALM BEACH GARDENS, Fla. , Jan. 15, 2014  In an ... C. difficile and TB in ambulances and other transport vehicles, an ... being used by rescue personnel for the first time. ... coming in contact with these deadly pathogens, West Palm ...
(Date:1/15/2014)... 2014  Echo Therapeutics, Inc. (Nasdaq: ECTE ) ... System as a non-invasive, wireless continuous glucose monitoring system, ... Chairman and Interim CEO of Echo Therapeutics, will present ... Conference. Mr. Doman will make a ...
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... & Forecast – Worldwide Analysis ... Pump Market Analysis ...
Breaking Medicine Technology:Superbugs No Longer Ride In Rescue Vehicles 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17
... April 18, 2012  CAQH® announced today that ... the Universal Provider Datasource® (UPD®), demonstrating that ... standard for self-reported provider data used to ... network directories, referrals and claims administration. ...
... Live has revealed further details of the newest event ... (SEA) 2012. Set to debut from 10-12 May 2012 at ... first trade show and exhibition of its kind to be ... CPhI SEA will provide a meeting place ...
Cached Medicine Technology:One Million Healthcare Providers Now Use the CAQH Universal Provider Datasource 2One Million Healthcare Providers Now Use the CAQH Universal Provider Datasource 3Leading Pharma Ingredients Event Debuts in Growing ASEAN Market 2Leading Pharma Ingredients Event Debuts in Growing ASEAN Market 3
(Date:4/24/2014)... A national response to the epidemic of prescription opioid ... England Journal of Medicine by leaders of agencies ... The commentary calls upon health care providers to ... and reduce overdose deaths, and describes a number of ... medications. The commentary also discusses how medications can be ...
(Date:4/24/2014)... NH, 4/24/14) Dartmouth has been awarded one of ... serve as a Lead Academic Participating Site in its ... Award recipients are a select groups of investigators charged ... fewer cooperative groups., The NCTN grant system reflects recommendations ... It streamlines operations to achieve four goals:, ...
(Date:4/24/2014)... scientist at the University of York reveals that a ... of the nervous system may also play a pivotal ... research team, led by Dr Will Brackenbury, a Medical ... York, has studied how voltage-gated sodium channels assist in ... in the membranes of excitable cells, such as neurons, ...
(Date:4/23/2014)... for a new experimental drug to treat acute ... with CPX-351, a combination of the chemotherapeutic drugs ... patients treated with the standard drug formulation. ... aggressive blood cancer with very low rates of ... Lancet, M.D., senior member of the Department of ...
(Date:4/23/2014)... 23, 2014 The American Society for Radiation Oncology ... of Postoperative Radiation Therapy for Endometrial Cancer: An ... adjuvant radiation therapy in the treatment of endometrial ... the May-June 2014 issue of Practical Radiation ... of ASTRO. The full-length guideline is available as ...
Breaking Medicine News(10 mins):Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 2Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 3Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 4Health News:Dartmouth awarded lead role in NCI clinical trials network 2Health News:Dartmouth awarded lead role in NCI clinical trials network 3Health News:Breast cancer replicates brain development process 2Health News:Moffitt Cancer Center's phase 3 study may be game-changer for acute myeloid leukemia 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 3
... done too soon can lead to respiratory trouble, other ... -- The rise in Caesarean deliveries could be fueling ... these early births carry risks, including respiratory problems, jaundice ... Tuesday during a March of Dimes conference in New ...
... been selected as the Grand Prize winner of the Jump Start ... ... Hudson, OH (PRWEB) December 18, 2008 -- A resident of ... the Jump Start ,09 national online sweepstakes sponsored by ActiveAmericans.com ...
... wellness center, will implement the C4 IP™ hosted VoIP and ... ... Atlanta, GA (PRWEB) December 18, 2008 -- ... implement the C4 IP™ hosted VoIP and ...
... recognize human gestures could provide a new way for ... related system for the able bodied could also be ... is described in detail in a forthcoming issue of ... , Manolya Kavakli of the Virtual and Interactive Simulations ...
... up after 3 years, study finds , , THURSDAY, Dec. 18 ... medication to prevent narrowing of the artery do better one ... stents, a new study shows. , However, within three years ... a greater risk of more surgery to increase blood flow ...
... Group-based treatment programs may effectively combat childhood obesity ... Florida study. , Children who participated in one of ... less overweight compared with children in a control group. ... Archives of Pediatric and Adolescent Medicine . , The ...
Cached Medicine News:Health News:Elective Early Deliveries Pose Risks for Babies 2Health News:Elective Early Deliveries Pose Risks for Babies 3Health News:Pittsburgh Area Resident Wins $15,000 In Online Sweepstakes 2Health News:MALO CLINIC Avoids Capital Expense and Gains Scalability with Hosted Unified Communications 2Health News:MALO CLINIC Avoids Capital Expense and Gains Scalability with Hosted Unified Communications 3Health News:MALO CLINIC Avoids Capital Expense and Gains Scalability with Hosted Unified Communications 4Health News:Gesture recognition 2Health News:Coated Stents Better Than Bare Metal Ones in Short Run 2Health News:Group treatment may help children achieve healthier weights 2Health News:Group treatment may help children achieve healthier weights 3
... in Canons DR innovations, the CXDI-31 is ... a compact and lightweight design, the Canon ... conventional screen-film cassettes. It is designed to ... to get with fixed devices and supports ...
... a cost-effective synthetic bone filler tailored ... Phosphate (TCP) and Hydroxyapatite (HAP), its ... BAB formulates the chemistry and microstructure ... This formulation provides optimal osteo-conduction. The ...
The Oscor PACE 101 H is an external single chamber cardiac demand pacemaker. The PACE 101 H feature an option for a atrial overdrive stimulation....
... TAU Lead is a ... stimulation lead for temporary ... The unique shaft design ... straight or preformed stylets ...
Medicine Products: