Navigation Links
Vermillion's Biomarkers Prove Beneficial in Identifying Women With Ovarian Cancer and Detecting Early-Stage Disease
Date:3/10/2008

the validation set, which is a critical step in diagnostic test development.

Positive Results in Early-Stage Disease Detection (Poster 080)

The ovarian cancer detection study showed that Vermillion's panel of biomarkers in combination with CA-125 could more accurately identify early- stage ovarian cancer than could CA-125 alone. CA-125 is the only tumor marker for ovarian cancer currently available on the market; however, it is not cleared for early-stage disease detection. When examining stage-1 disease, the combination of the two markers correctly identified 87 percent of the cancers.

The study trained a model on pre-operative serum samples from 231 patients, and then tested the model on pre-operative serum samples from 450 patients. Vermillion worked in collaboration with Robert C. Bast, Jr., M.D. and colleagues from the University of Texas M.D. Anderson Cancer Center on this research.

New Ovarian Biomarkers on the Horizon (Poster 175) Another study found that calgranulin A and B, two proteins commonly found in malignant ovarian cysts, may be useful in helping diagnose and predict prognosis of ovarian cancer.

Researchers at Vermillion and the University of Kentucky Chandler Medical Center used surface enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF) to analyze ovarian cyst fluids and identify the underlying proteins that could serve as potentially useful biomarkers for ovarian cancer. Fluids from benign (n=45), malignant (n=15), and low malignant potential (n=13) ovarian tumors were examined. The calgranulin proteins were increased in malignant ovarian cyst fluids as compared to benign cyst fluids (p<0.001).

About Vermillion's Ovarian Cancer Diagnostic Program

Vermillion has multiple ovarian cancer diagnostic tests in development. The most advanced of Vermillion's programs is the Ovarian Tumor Triage Test, which utilizes a panel of biomarkers to help identify women with cancer so t
'/>"/>

SOURCE Vermillion, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. JDRF and Lilly Partner to Fund Research to Identify Beta Cell Biomarkers
2. Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
3. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
4. New Study Proves That Minimally Invasive Aneurysm Treatment Yields Successful Long-Term Results
5. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
6. Experimental Drug Ketasyn(TM) Improves Memory in Age-Associated Memory Impairment Study
7. Study Shows Combination Therapy Incorporating AVODART(R) and Tamsulosin Provides Continuous Symptom Improvement Over 2 Years
8. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
9. First Osteoporosis Study in Hip Fracture Patients Finds Once-Yearly Reclast(R) Prevents Additional Fractures and Improves Survival
10. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
11. One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2009)... Dynatronics Corporation (Nasdaq: ... vendor agreement to provide therapy equipment and rehab ... nationwide network of physical, occupational and speech therapy ... Preferred Therapy Providers," said Larry K. Beardall, executive ... "Their vast network of 1,100 clinics is the ...
(Date:12/15/2009)... NEW YORK, Dec. 15 ... research report is available in its ... - Drug Pipeline Analysis and Market ... http://www.reportlinker.com/p0167308/Systemic-Lupus-Erythematosus---Drug-Pipeline-Analysis-and-Market-Forecasts-to-2015.html ,, Systemic Lupus ... Market Forecasts to 2015 ,, ...
(Date:12/15/2009)... Dec. 15 Waters Corporation ... SDMS Vision Publisher(TM) (v.7.1 SR4), an electronic laboratory ... System (SDMS), a secure electronic repository that stores ... a centralized database and is used to boost ... compliant with the SAFE-BioPharma digital identity and signature ...
Breaking Medicine Technology:Dynatronics Inks Preferred Vendor Agreement with 1,100 Member Preferred Therapy Providers, Inc. 2Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 2Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 3Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 4Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 5Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 6Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 7Reportlinker Adds Systemic Lupus Erythematosus - Drug Pipeline Analysis and Market Forecasts to 2015 8Waters SDMS Vision Publisher Now Certified Compliant with SAFE-BioPharma Digital Standard 2Waters SDMS Vision Publisher Now Certified Compliant with SAFE-BioPharma Digital Standard 3Waters SDMS Vision Publisher Now Certified Compliant with SAFE-BioPharma Digital Standard 4Waters SDMS Vision Publisher Now Certified Compliant with SAFE-BioPharma Digital Standard 5Waters SDMS Vision Publisher Now Certified Compliant with SAFE-BioPharma Digital Standard 6Study examines ethical dilemmas of medical tourism 59054 1Study examines ethical dilemmas of medical tourism 59054 2Satellite data instrumental in combating desertification 10283 1Satellite data instrumental in combating desertification 10283 2Satellite data instrumental in combating desertification 10283 3Biotechnology Can Address Global Mega Trends DuPont Leader Says 14382 1Biotechnology Can Address Global Mega Trends DuPont Leader Says 14382 2Biotechnology Can Address Global Mega Trends DuPont Leader Says 14382 3
... 12, 2007—InB:Biotechnologies, Inc.,("BioTech"), a wholly-owned subsidiary of ... positive results in,studies of vaccines against HPV, ... AIPwLV™ vaccine technology. The,studies were conducted by ... the Contract Research Organization led by Dr.,Vidadi ...
... Demonstrates Good Safety Profile and Excellent,Pharmacokinetic Properties -, ... --,CeNeRx BioPharma, Inc., a clinical stage company developing ... system, today announced top-line results from a Phase ... the treatment,of depression and anxiety. In this study, ...
Other Medicine Technology:Integrated BioPharma's Proprietary Vaccine Technology Achieves,Strong Positive Results 2CeNeRx BioPharma Announces Positive Phase I Results in First Human,Trial of Third Generation RIMA Antidepressant 2CeNeRx BioPharma Announces Positive Phase I Results in First Human,Trial of Third Generation RIMA Antidepressant 3
(Date:12/15/2009)... suicide goes up within a week of getting ... News) -- Emotional stress can put newly diagnosed ... events and suicide, a new study has found. ... diagnosed with prostate cancer between 1961 and 2004. ... cardiovascular event within a year of cancer diagnosis ...
(Date:12/15/2009)... R.I., Dec. 15 Mergers and acquisitions ... expand their reach globally or complete a product ... the integration of safety programs. ,, A new ... Best Practices in a Hearing Conservation Program: US ... Airways and America West led the newly formed ...
(Date:12/15/2009)... by the Technology-based Learning SIG of ASTD,s Atlanta ... eLearning designs. This year nominees, eleven (11) ... The Venza Group entry, a highly engaging modular ... selected as the winner of the "Greater Than ... panel of distinguished judges. While announcing the ...
(Date:12/15/2009)... Inhibiting fatty acid synthesis in brain cancer cells may ... of deadly glioblastomas that are driven by amplified signaling ... a first-of-its-kind study by researchers at UCLA,s Jonsson Comprehensive ... acids for the formation of new membranes. The fatty ... cancer cells, and may be important for regulating cell ...
(Date:12/15/2009)... scientists have found the first potential immunological clue of ... the pandemic H1N1 virus. , The study analyzed ... 15 outpatients and 15 control subjects in 10 Spanish ... August 2009. Researchers from the Hospital Clinico Universitario de ... high levels of a molecule called interleukin 17 in ...
Breaking Medicine News(10 mins):Health News:New White Paper Details Best Practices of an Occupational Hearing Conservation Program: US Airways 2Health News:New White Paper Details Best Practices of an Occupational Hearing Conservation Program: US Airways 3Health News:New White Paper Details Best Practices of an Occupational Hearing Conservation Program: US Airways 4Health News:The Venza Group Received Top Honors at the American Society of Training & Development (ASTD) eLearning Excellence Awards Ceremony Held on December 10, 2009 2Health News:Targeting brain cancer cell metabolism may provide new treatment 2Health News:Targeting brain cancer cell metabolism may provide new treatment 3Health News:First immunological clue to why some H1N1 patients get very ill or die 2
... According to a Norwegian study of 1656 subjects over an ... in the workplace is linked to a significant increase in ... and its surroundings were enrolled in 1985 and asked about ... asthma. ,Then, after 5 years 1656 of the ...
... type 2 diabetes. According to a new survey, they showed ... been selected for a pancreas transplant.// Obesity is a strong ... the immune system destroys the insulin-producing cells of the pancreas. ... insulin, usually in the middle age. ,Pancreas transplantation, ...
... preserve their voice box. Treatment for laryngeal cancer often includes ... to learn to speak through an opening made in the ... that has a drastic impact on the quality of that ... been looking into other treatment approaches for laryngeal cancer. In ...
... is a slow killer that ticks away in one out ... These were among the facts and figures trotted out on ... Day. Gathered in front of the Victoria Statue, Cubbon Park, ... the City Police, and the Bangalore Metropolitan Transport Corporation (BMTC). ...
... Stress on human life has been increasing day by day.It ... a more healthy and peaceful life style.//This article is ... get angry for trivial things which does not concern us.But ... life threatning cardiac arrest in patients with heart disease by ...
... there's a firm connection between viral infection and pre-cancerous lesions ... human papillomavirus (HPV)// may increase the risk of cervical cancer. ... history of abnormal cervical cell growth were followed for ten ... another two years later. Those who were free of HPV ...
Other Medicine News:
The Escape Basket offers a side-by-side approach, unique to the market, for using a nitinol basket and holmium laser fiber together-providing physician control and independent manipulation of both th...
Simple, Effective Laparoscopic Irrigation Pumps from the Market Leader...
The Surgiflex WAVE XP couples the state-of-the-art Surgiflex WAVE Probe with the convenience of a truly portable battery-powered pump....
... is a minimally invasive, highly effective surgical ... incontinence. GYNECARE TVT is positioned close to ... and when needed, TVT provides tension-free support ... The procedure takes approximately 20 to 30 ...
Medicine Products: