Navigation Links
Vermillion Announces Positive Top-Line Results from the OVA500 Multi-Center Study Led by UC Irvine
Date:7/30/2012

AUSTIN, Texas, July 30, 2012 /PRNewswire/ -- Vermillion, Inc. (NASDAQ: VRML), a leading molecular diagnostics company, today announced positive results from a new prospective, multi-center clinical study of its ovarian cancer diagnostic OVA1®. The study, referred to as OVA500, was led by Dr. Robert E. Bristow, director of Gynecologic Oncology Services at UC Irvine Healthcare in Orange, CA, and deputy editor of the journal Gynecologic Oncology.

OVA1 is a blood test for pre-surgical assessment of ovarian tumors for malignancy using a unique multi-biomarker approach. As the first protein-based, in vitro diagnostic multivariate index assay cleared by the U.S. Food and Drug Administration, OVA1 represents a new class of software-based diagnostics.

The OVA500 study confirms and extends the pioneering work of Dr. Fred Ueland published last year. It was a prospective, multi-institutional, blinded study with a new cohort of 494 patients representing the intended use population for OVA1: female patients who were scheduled to undergo surgery for an adnexal mass, enrolled from non gynecologic oncology practices via 27 study coordination centers.

All adnexal tumor types were included in the statistical analysis of test performance. The primary objective was to assess the performance of OVA1 in the intended use population with a focus on two particularly challenging subgroups: women with early-stage ovarian cancer, where approximately half of patients have a normal CA125 level, and pre-menopausal women, where the incidence of ovarian cancer is low and incidence of benign cysts is high.

Top-line data from the study are as follows:

Overall Performance of OVA1

  • Negative predictive value was reported at 98%
  • Sensitivity was reported at 96%
  • Specificity was reported at 51%

Performance in the Pre-menopausal Population


    '/>"/>

SOURCE Vermillion, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Vermillion PAD Intended Use Study Presented at Society for Vascular Medicine 23rd Annual Scientific Sessions
2. Vermillion Announces CEO Succession Plan
3. Vermillion Sets First Quarter 2012 Conference Call for Tuesday, May 15, 2012 at 4:30 p.m. ET
4. Insmed Announces Planned Departure Of Chief Financial Officer
5. Absorption Systems announces novel test platform for interactions with the BCRP transporter
6. Novogen Announces Merger Agreement With Kai Medical And Distribution Of Mei Pharma Shares
7. Aethlon Medical Announces the Appointment of Thomas V. Wornham and Philip A. Ward to its Board of Directors
8. IRIDEX Announces Second Quarter 2012 Conference Call and Release Date
9. Gentris Corporation Announces Collaboration to Study Blood Stability
10. RoundTable Healthcare Partners Announces Sale of Aspen Surgical Products Holding, Inc. to Hill-Rom Holdings, Inc.
11. Biomet Announces Pricing of Senior Notes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... , Dec. 23, 2014   Synageva BioPharma ... biopharmaceutical company developing therapeutic products for rare disorders, ... (EMA) of the Marketing Authorization Application (MAA) for ... granted the company,s request for accelerated assessment, which ... review time.   The MAA, and ...
(Date:12/24/2014)... -- In response to urgent requests from the Deputy Minister of ... , Direct Relief delivered two 10-bed medical tents to ... local health workers who contract Ebola while fighting the outbreak. ... was constructed for foreign health care workers who may contract ... Sierra Leonean health workers. With Sierra ...
(Date:12/22/2014)... , Dec. 22, 2014 Apnea Sciences ( ... offices in Aliso Viejo , California.  ... to the tremendous growth and worldwide expansion, a new ... patented SnoreRx, the anti snore cure have exceeded our ... "We are now in 23 countries and will ...
Breaking Medicine Technology:Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3First Ebola Treatment Unit for Local Health Workers Arrives in Sierra Leone 2
... INDIANAPOLIS, Jan. 18, 2011 Eli Lilly and Company (NYSE: ... the fourth quarter and full year of 2010 on Thursday, ... on that day with the investment community and media to ... conference call will be held from 9:00 a.m. to 10:00 ...
... Jan. 18, 2011 DW Healthcare Partners (DWHP), a ... announced the appointment of Bradley Lanham as the new ... DWHP has now completed acquisitions of institutional pharmacies specializing ... including Texas, Nevada, Utah, Idaho and Colorado. ...
Cached Medicine Technology:DW Healthcare Partners Announces New CEO on Heels of Increased Investment in Institutional Pharmacy Sector 2
(Date:12/25/2014)... 25, 2014 Residents at ... recently showed their generous spirit by providing holiday ... County Parenting Network- Grandparents Raising Grandchildren program. , ... around the largest Christmas tree on the campus ... by residents of the Abernethy Village Association (AVA). ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping ... items. During the holiday season, AlignLife looks forward to their ... says Dr. Sara Mahalko-Leonhardt, owner of AlignLife. "It brings our ... that we are able to give kids toys for Christmas ... for the generosity of our patients." , The 70 toys ...
(Date:12/24/2014)... (PRWEB) December 24, 2014 Connie Casad, ... and functional medicine advocate with 30 years of practice ... to evaluate the health benefits of dietary detoxification. The ... new participants following excellent results from test patients who ... asked to explain her interest in conducting the study, ...
(Date:12/24/2014)... 2014 New studies reveal that women under ... related depression (March 6, 2014, JAMA Otolaryngology*). And although many ... (about 50 percent according to recent polls) facing hearing loss ... a person feels and relates to the world. People who ... also made by way of:, , self-confidence ...
(Date:12/24/2014)... December 25, 2014 Today, UWDress.com, the famous ... sleeve wedding gowns, and launched a site-wide wedding gown promotion. ... sleeve wedding gowns in a more unexpected way, the collection ... are popular in the global market, and they are available ... UWDress.com are offered at discounted prices, up to 75% off; ...
Breaking Medicine News(10 mins):Health News:Retirement Community Residents Make Impact During Holiday Season 2Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 2Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 4Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 5Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 6Health News:Buy Cheap Long Sleeve Wedding Gowns At UWDress.com 2
... Wound ... ... Medical Technologies , Inc. today announced that its new HemCon Nasal Plugs and Seal-On devices ... The nasal care products will be available from HemCon directly to consumers under ...
... to keep beach underfoot than to dig in it, survey ... the dangers that lurk in sand castles, researchers warn. , ... of North Carolina at Chapel Hill have found that beachgoers ... at higher risk of developing diarrhea and gastrointestinal diseases than ...
... mathematics to take the guesswork out of efforts to ensure ... body parts will have enough blood and oxygen to survive ... model of tissue transfer, mathematicians have shown that they can ... transfer from one part of the body to another location ...
... MONTCLAIR, N.J., July 14 Parentgiving.com, the only comprehensive online resource ... aging parents, announces the launch of the first annual Parentgivers ... honor six selfless caregivers who care for an aging adult while ... July 13 via the Parentgiving website ( www.Parentgiving.com ) ...
... , TOLOCHENAZ, Switzerland, July 14 ... Approval for Medtronic,s Reclaim(R) DBS Therapy for Treatment,of Chronic, ... today announced that Reclaim(R) Deep Brain Stimulation (DBS),Therapy has ... chronic, severe treatment-resistant obsessive-compulsive,disorder (OCD).* This is the first ...
... Users, Guide, a comprehensive resource for endovascular and ... both book and CD formats. This unique reference ... Radiology, a national organization of physicians, scientists and ... through disease management and minimally invasive, image-guided therapeutic ...
Cached Medicine News:Health News:New HemCon/Seal-On Nasal Plugs Control Nosebleeds Quickly, Effectively and Comfortably 2Health News:New HemCon/Seal-On Nasal Plugs Control Nosebleeds Quickly, Effectively and Comfortably 3Health News:Germs Hold Court in Sand Castles 2Health News:Mathematics taking guesswork out of plastic surgery tissue transfer 2Health News:Mathematics taking guesswork out of plastic surgery tissue transfer 3Health News:Mathematics taking guesswork out of plastic surgery tissue transfer 4Health News:Nominate the Parentgivers of the Year 2Health News:World's First Deep Brain Stimulation Device Approved for Treatment of Psychiatric Condition in Europe 2Health News:World's First Deep Brain Stimulation Device Approved for Treatment of Psychiatric Condition in Europe 3Health News:World's First Deep Brain Stimulation Device Approved for Treatment of Psychiatric Condition in Europe 4Health News:New: Interventional radiology coding users' guide 2
... This requiring no water ... long-lasting hand hygiene to physically ... washing is either not an ... Hibistat allows you to return ...
BETASEPT® Scrub 4% is for surgical handscrubbing, healthcare personnel hand-washing, preoperative patient prepping and general skin degerming....
... The Scrub Care® Brand soaps, emulsions, ... the ultimate in healthy skin care, ... keeping skin healthy and soft even ... do not contain petroleum-based substances that ...
... Scrub Care Scrub Brushes & ... choices to meet the demanding needs ... a preimpregnated scrub brush or prefer ... with bottled antimicrobial solution, scrub brushes ...
Medicine Products: