Ventana licenses Gen-Probe IP for measuring ERG protein in prostate cance... (does not occur in healthy tissue and des...)

Ventana licenses Gen-Probe IP for measuring ERG protein in prostate cancer patients

Date:5/21/2012

does not occur in healthy tissue and describes a molecular subtype of prostate cancer that is associated with androgen driven prostate cancer. As this subtype is the most prevalent in prostate cancer, there has been tremendous diagnostic, prognostic and predictive interest in the ERG biomarker.

"We are extremely enthusiastic to see the rapid development of robust clinical tests to determine the ERG rearrangement status in patient samples," says Mark A. Rubin, M.D., Hormer T. Hirst, Professor of Oncology in Pathology, Weill Cornell Medical College of Cornell University and New York Presbyterian Hospital. "Emerging molecular and clinical data strongly support the view that prostate cancer is a collection of molecularly distinct diseases that will have different disease trajectories and responses to treatment. Accurately defining the ERG rearrangement class, the largest molecular subclass known to date, is a critical step towards precision health care for prostate cancer."

Ventana has ERG IVD assays available globally-- including assays for ERG protein via IHC (worldwide IVD) and assays for ERG gene rearrangements via Quantum Dot FISH (CE-IVD)--and the company is developing multivariate assays for novel clinical indications. These assays are available for use on the VENTANA BenchMark line of fully-automated advanced staining instrumentation utilized by thousands of anatomic pathology labs worldwide.

About Ventana Medical Systems, Inc.
Ventana Medical Systems, Inc. ("VMSI") (SIX: RO, ROG; OTCQX: RHHBY), a member of the Roche Group, innovates and manufactures instruments and reagents that automate tissue processing and slide staining for cancer diagnostics. VENTANA solutions are used in clinical histology and drug development research laboratories worldwide. The company's intuitive, integrated staining, workflow management platforms, and dig
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