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Varian's Calypso Tumor Tracking System Used in Lung, Stomach and Prostate Cancer Treatments at Leading European Cancer Center
Date:9/30/2013

ose stereotactic ablative body radiotherapy (SABR).  "Real-time tracking of motion is vital if the tumor is close to a critical structure," says Professor Greco. "These surface transponders detect truly valuable information that can enhance precision and allow us to stop the treatment if the target moves beyond a certain threshold."

Professor Greco cited an example of a Calypso surface transponder detecting a tiny lateral movement during a thoracic treatment. "The patient, who had an extremely consistent breathing pattern, admitted that she swallowed right at the end of the treatment and the transponder detected this and we were able to respond accordingly," he said. "A surface mounted device can tell you a lot about what is happening inside the body, enabling you to make corrections to the set-up during the treatment."

Professor Greco presented a paper at last week's American Society for Radiation Oncology (ASTRO) meeting in Atlanta highlighting the use of Calypso surface transponders during a SABR treatment for mediastinal adenopathy at CCU.

Clinicians at CCU have also introduced hypo-fractionated prostate cancer treatments for patients with low and intermediate risk tumors. Instead of the typical delivery schedule of 28 daily treatments over six weeks, patients are being treated in five sessions over ten days. "As each daily dose is much higher, precision is vital and with the help of the Calypso device we are able to more effectively minimize impact to the rectal wall and urethra," said Professor Greco. A phase 1 clinical trial has been initiated to validate this approach.

"The preliminary data appears extremely encouraging," adds Professor Greco. "The quality of set-up and rigorous monitoring enabled by the Calypso transponders allows us to test the efficacy and safety of such high-dose image-guided radiotherapy treatments."       

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