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Vantia Therapeutics Raises £4 Million to Fund Clinical Development of its Lead Compounds
Date:7/6/2011

benign prostatic hypertrophy (BPH). This population forms the largest part of the nocturia market and represents the greatest unmet need. The results of this trial are expected in the second half of 2011 and will be used to support the design of pivotal clinical trials. Data from previous clinical trials, presented at the American Urological Association meeting in 2010, demonstrated a dose-dependent pharmacological effect and suggested that VA106483 has the potential to be an effective and well tolerated antidiuretic for the treatment of nocturia.

About Vantia Therapeutics:

Vantia Therapeutics is an emerging pharmaceutical company developing novel, small molecule drugs targeting large areas of unmet medical need. Its strong clinical pipeline includes VA106483 for nocturia and VA111913 for dysmenorrhoea, which directly target indications that together affect many millions of people, are poorly treated and represent billion dollar markets. Vantia's strategy is to develop its proprietary drug candidates through Phase II clinical testing and then commercialise through partnerships. The Company was founded in 2008 and is backed by specialist life science investors Novo A/S, SV Life Sciences and MVM Life Science Partners.

http://www.vantiatherapeutics.com

VA106483 - Nocturia

VA106483 is a novel small molecule drug candidate discovered by Vantia Therapeutics and is in Phase II trials to treat nocturia, a common condition that causes sufferers to wake frequently during the night in order to urinate, thus interrupting sleep. VA106483 acts directly in the collecting ducts of the kidney by binding to vasopressin V2 receptors.

Nocturia increases markedly with age and is often the presenting symptom in men with benign prostatic hypertrophy (BPH), affecting at least 70% of the more than 15 million BPH patients in the United States and Europe. Treatments for
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SOURCE Vantia Therapeutics
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