Navigation Links
Vanda Pharmaceuticals Initiates Phase III Clinical Study Aimed at Resetting the Body Clock
Date:8/26/2010

ROCKVILLE, Md., Aug. 26 /PRNewswire-FirstCall/ -- Vanda Pharmaceuticals Inc. (Nasdaq: VNDA), today announced it has initiated a Phase III clinical trial to evaluate tasimelteon in patients with Non-24-Hour Sleep Wake Disorder (N24HSWD), a condition experienced primarily by totally blind individuals that results in abnormal night sleep patterns and chronic daytime sleepiness.  Tasimelteon binds to high affinity melatonin receptors located in the brain that are believed to regulate circadian rhythms, or sleep/wake cycles.

"Blind individuals with no light perception do not receive external light and darkness signals that synchronize our internal body clocks," commented Mihael H. Polymeropoulos, M.D. President and Chief Executive Officer of Vanda.  "As a result, these individuals can live lives in a constant state of circadian misalignment.  Tasimelteon has the potential to be the first in the class of circadian regulators, drugs that may offer clinical benefits to patients with aberrant timing of the sleep/wake cycle."

About Study VP-VEC-162-3201

Vanda Study 3201 is designed to investigate the efficacy and safety of 20 mg tasimelteon versus placebo in totally blind individuals with N24HSWD, with a target enrollment of 160 individuals. The study includes a 6-month treatment period and an optional open-label extension. The primary endpoint of the study is improvement in Total Sleep Time (TST) during the night.  The study will also measure parameters of daytime sleep and laboratory measures of the synchronization between the internal body clock and the 24-hour environmental light/dark cycle. Vanda expects to report top-line results for this trial in the fourth quarter of 2011.

For more information about the clinical study please visit:

http://www.vandapharma.com/tasi3201.html<
'/>"/>

SOURCE Vanda Pharmaceuticals Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Vanda Pharmaceuticals Submits Iloperidone New Drug Application
2. Vanda Pharmaceuticals Reports Third Quarter 2007 Results
3. Vanda Pharmaceuticals Receives FDA Acceptance of Iloperidone New Drug Application
4. Vanda Presents Phase III Iloperidone Efficacy Data
5. Phase III Data Show Vanda Pharmaceuticals Tasimelteon (VEC-162) Significantly Improves Sleep in Patients with Chronic Insomnia
6. Vanda Pharmaceuticals Provides Update on Iloperidone
7. Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet
8. FDA Approves Vanda Pharmaceuticals Fanapt(TM) for the Treatment of Schizophrenia
9. Vanda Pharmaceuticals Enters into an Exclusive License Agreement for the Commercialization and Development of Fanapt(TM) in the U.S. and Canada for the Treatment of Schizophrenia
10. Vanda Pharmaceuticals Announces Expiration of Hart-Scott -Rodino Waiting Period for Exclusive License of Fanapt(TM)
11. Vanda Pharmaceuticals Announces U.S. Patent Allowance for a Long-Acting Injectable Formulation of Fanapt(TM) (iloperidone) in the U.S.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... CHENGDU, China , Jan. 23, 2015 Tianyin ... pharmaceutical company that specializes in the development and sale ... branded generics and active pharmaceutical ingredients (API) today announced ... Facility (JCM) API operation. 1. Following the ...
(Date:1/22/2015)... /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" or the "Company"), ... for cardiovascular disease and overall health is pleased to provide ... and its outlook for 2015 from the CEO, Mr. ... We would like to take this opportunity to share with ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... "Infectious Disease Diagnostics Market by Product, Application, Technology, ... to their offering. , The infectious disease ... 7.9% to reach $18,156.2 million by 2019 from $12,422.8 ...
Breaking Medicine Technology:TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 2Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 3
... Calif., Aug. 20 Jazz Pharmaceuticals, Inc. (Nasdaq: ... Committee of the U.S. Food and Drug Administration (FDA), ... and Risk Management Advisory Committee, voted 20-2 that the ... for the treatment of fibromyalgia with the currently proposed ...
... Cumberland Pharmaceuticals Inc.(Nasdaq: CPIX ) today ... its review of the supplemental new drug application (sNDA) for ... with non-acetaminophen acute liver failure. The review has been extended ... Fee Act (PDUFA) goal date in December 2010. ...
Cached Medicine Technology:Jazz Pharmaceuticals Provides Update on FDA Advisory Committee Meeting For JZP-6 (Sodium Oxybate) in Fibromyalgia 2Cumberland Pharmaceuticals Announces Extension of FDA Review of Acetadote® Supplemental New Drug Application 2Cumberland Pharmaceuticals Announces Extension of FDA Review of Acetadote® Supplemental New Drug Application 3
(Date:1/22/2015)... The City of West Hollywood hosted a news conference on ... anniversary of the Supreme Court decision Roe v. Wade, which legalized ... the Roe vs. Wade decision and the fight to protect a ... City of West Hollywood Councilmember Abbe Land. “We need to continue ...
(Date:1/22/2015)... 2015 Gabe’s Chemo Duck Program is pleased to ... app ever created for kids with cancer. The Chemo Duck App, ... is filled with enjoyable games to help children of all ages ... app helps to keep kids entertained, educated and at ease while ...
(Date:1/22/2015)... 23, 2015 VogueQueen is a seasoned and ... and many designers are thrilled to have it lead the ... its new collection of prom dresses for the global market. ... the strategic vision and he focuses on continuing the goal ...
(Date:1/22/2015)... 2015 Angelweddingdress is a famous wedding dress ... customers to follow it on Facebook, Twitter, and Pinterest. The ... gift. Angelweddingdress draws a lottery every week. , Moreover, the ... 28, 2015. Click Angelweddingdress homepage for more information. ...
(Date:1/22/2015)... 23, 2015 AngelWeddingDress, the premier women’s ... maternity wedding dresses. View website of AngelWeddingDress.com ... for maternity wedding dresses online for a bridal party. ... high quality for them. Its maternity wedding dresses are ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2
... so will potential risks, researcher warns , FRIDAY, May ... defibrillators and cochlear implants, are becoming vulnerable to "infection" ... To prove his point, Mark Gasson, a scientist at ... himself to become "Exhibit A." , Gasson said he ...
... (May 28, 2010)Cancer of the pancreasa glandular organ ... and hormonesseldom is detected in early stages, making treatment ... research from Fox Chase Cancer Center finds that patients ... chemotherapy and radiation survive four times as long, on ...
... ... ... Clubs International Foundation (LCIF), will appear in Monday’s National Memorial Day Parade along ... who are Lions Clubs members. , , ,One of the WWII veterans on the float will ...
... ... solutions arena with the addition of two respected Atlanta-area surgical assistant practices: Omni Surgical ... ... (JSA) has expanded its national presence in the practice management solutions arena with the ...
... Khanna ... ... have had a symbiotic relationship to advance vision in people suffering from presbyopia or cataracts. ... RK or macular degeneration. The Crystalens is the only FDA approved accommodating intraocular lens ...
... are studying the role that statins lifesavers for tens ... play in causing disabling tendon ruptures. Francesca Dwamena, ... of Medicine, is leading the study, which will analyze more ... by a grant from the Blue Cross Blue Shield of ...
Cached Medicine News:Health News: Scientist Becomes First Human 'Infected' With Computer Virus 2Health News:Response to preoperative therapy may predict survival in pancreatic cancer patients 2Health News:Chairman Al Brandel of Lions Clubs International Foundation to Appear in Washington DC's National Memorial Day Parade 2Health News:Jackson Surgical Assistants Expands Its National Presence by Merging with Two Atlanta Area Practices 2Health News:Jackson Surgical Assistants Expands Its National Presence by Merging with Two Atlanta Area Practices 3Health News:Khannna Institute to offer Crystalens in Quarter Diopter Steps 2Health News:MSU team studies connection between statins, tendon ruptures 2
Six inch wide elastic belt transfers the apron weight off the shoulders. 0.5mm front and 0.25mm back with a generous overlap for double protection. Shoulder pads included. Also available without wide...
6" wide elastic belt transfers the apron weight off the shoulders to the hips making this apron the most comfortable for long procedures. Adjustable. Velcro keeps apron snug....
... single-use, direct current stimulator ... 0.5, 1.0, and 2.0mA ... needle as the grounding ... flow" confirmation light is ...
The NS242 is a base level constant current Conventional Peripheral Nerve Stimulator only. It uses conventional stimulation patterns only to monitor neuromuscular blocks i.e. Single Twitch, Train of F...
Medicine Products: