Navigation Links
Valeant Pharmaceuticals Announces Publication of Efinaconazole Phase III Results
Date:11/26/2012

MONTREAL, Nov. 26, 2012 /PRNewswire/ -- Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX) announced today that the Journal of the American Academy of Dermatology has published the positive results from our two pivotal, international,  multicenter, randomized, double-blind, vehicle-controlled studies that were conducted in 1,655 subjects with onychomycosis. Onychomycosis is a common nail infection caused predominantly by dermatophyte fungi, resulting in nail destruction and deformity. The only approved topical treatments are lacquers with very limited efficacy. Oral treatments, while more efficacious, are limited by drug interactions and numerous safety concerns including the potential for acute liver injury. Valeant investigated the safety and efficacy of efinaconazole 10% topical solution (efinaconazole), the first triazole antifungal agent developed for distal lateral subungual onychomycosis (DLSO).

The study's primary endpoint was stringently defined as the complete cure rate at Week 52, which means that the target nail showed no clinical involvement and no evidence of fungus present by both KOH testing and a negative fungal culture. In Study 1, 17.8% of subjects treated with efinaconazole were completely cured, as compared to only 3.3% of subjects treated with vehicle and in Study 2, 15.2% of subjects treated with efinaconazole were completely cured, as compared to only 5.5% of subjects treated with vehicle. Using the secondary endpoint of complete or almost complete cure, defined as < 5% clinical involvement and 100% mycologic cure, the success rates for efinaconazole increased to 26.4% and 23.4%, respectively.  The adverse events that were reported were generally mild and transient and were similar between subjects treated with efinaconazole solution 10% and vehicle.

"We are pleased to share the positive resu
'/>"/>

SOURCE Valeant Pharmaceuticals International, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Valeant Pharmaceuticals Agrees To Acquire AcneFree And Certain Assets From University Medical
2. Valeant Pharmaceuticals Reports 2012 First Quarter Financial Results
3. Valeant Pharmaceuticals To Host Investor Day
4. Valeant Pharmaceuticals To Announce 2012 Second Quarter Results On August 2, 2012
5. Valeant Pharmaceuticals International, Inc. Agrees To Acquire Medicis Pharmaceutical Corporation For $44.00 Per Share In Cash
6. Valeant Pharmaceuticals To Present At UBS Annual Global Life Sciences Conference
7. Valeant Pharmaceuticals Announces Management Change
8. Valeant Pharmaceuticals To Syndicate Incremental Loans
9. Valeant Pharmaceuticals Appoints Howard Schiller To Board Of Directors
10. Valeant Pharmaceuticals Announces Launch of Concurrent Private Offerings of Senior Notes
11. Valeant Pharmaceuticals International, Inc. Announces Pricing Of Concurrent Private Offerings Of Senior Notes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... 2015  Fort Lauderdale-based investment banking firm, Farlie ... its Consumer Group completed the sale of Insight ... (ISE: KRZ) ("Kerry"), one of the leading global ... well as functional ingredients and actives for the ... served as the exclusive financial advisor to the ...
(Date:7/2/2015)... June 26, 2015 Research and ... "Vitamin D Market by Analog, Application, End-User & by Region ... their offering. This market is projected to reach ... D in different applications and rising opportunities in countries such ... , Italy , and Brazil ...
(Date:7/2/2015)... MUMBAI , July 2, 2015 ... equity stake in ZAO "Biocom" in Russia ... foray into the Russian pharmaceutical market which recorded RUB 765 ... 10 pharmaceutical markets in the world in 2014 (IMS Health). ... growth and expected to continue with this trend, projecting ...
Breaking Medicine Technology:Farlie Turner's Consumer Group Completes Sale of Insight Beverages to Kerry 2Vitamin D Market by Analog, Application, End-User & by Region - Global Trends & Forecast to 2020: Increasing Recommendation By Doctors & Associations 2Vitamin D Market by Analog, Application, End-User & by Region - Global Trends & Forecast to 2020: Increasing Recommendation By Doctors & Associations 3Lupin Acquires Biocom in Russia 2Lupin Acquires Biocom in Russia 3
... , SAN DIEGO, Nov. 24 Anadys Pharmaceuticals, Inc. (Nasdaq: ... the 21st Annual Piper Jaffray Healthcare Conference on Tuesday, December ... The conference is being held at The New York Palace ... of Anadys, will provide an overview of Anadys and its ...
... , SAN ... marketer of the VerifyNow® System, the first rapid and easy-to-use ... agents (e.g. Plavix® and aspirin), announced today that Timothy I. ... Chief Financial Officer of Accumetrics, will be presenting a corporate ...
Cached Medicine Technology:Anadys Pharmaceuticals to Present at the Piper Jaffray Healthcare Conference 2Accumetrics to Present at the 21st Annual Piper Jaffray Health Care Conference 2
(Date:7/2/2015)... (PRWEB) , ... July 02, 2015 , ... In 2012, Patrick Achebe realized that the ... was alone. He sat down to write his first poem, and three years later he ... that was special and worth sharing with the world. "I have always believed that the ...
(Date:7/2/2015)... ... July 02, 2015 , ... Global leader and compression innovator, SIGVARIS ... for men. , For style that’s quick on its feet, men will love ... great news for men everywhere because a simple change in socks can dramatically help ...
(Date:7/2/2015)... ... July 02, 2015 , ... When The American ... the late June Web-based session, the speakers discussed the importance of accountable care ... patients through coordinated care. , During the session, participants learned the ins and ...
(Date:7/2/2015)... Newport Beach, CA (PRWEB) , ... July 02, ... ... learning surgical procedures and executing them with care and precision. There is an ... Sadati, FAACS, has had the honor of successfully reshaping the facial features and ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... (CVR) recently received nearly $4 million through five federal grants to study a ... therapies against the deadly diseases. , The research will be conducted in ...
Breaking Medicine News(10 mins):Health News:Patrick Achebe Releases Debut Book, Whispering Waves: Poems for Everyday Grace 2Health News:SIGVARIS Kicks Up Its Style for Men with the Launch of MIDTOWN MICROFIBER in a Dark Navy Stripe Pattern 2Health News:SIGVARIS Kicks Up Its Style for Men with the Launch of MIDTOWN MICROFIBER in a Dark Navy Stripe Pattern 3Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 2Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 3Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 4Health News:Dr. Kevin Sadati Featured in July Issue of Popular National Magazines 2Health News:Dr. Kevin Sadati Featured in July Issue of Popular National Magazines 3Health News:Mosquito-Borne Viruses Subject of $4M in Federal Grants to Scientists in Pitt’s Center for Vaccine Research 2Health News:Mosquito-Borne Viruses Subject of $4M in Federal Grants to Scientists in Pitt’s Center for Vaccine Research 3Health News:Mosquito-Borne Viruses Subject of $4M in Federal Grants to Scientists in Pitt’s Center for Vaccine Research 4
... YORK, Jan. 27 Today, Care to Care announced ... Officer and Senior Vice President. "Following an extensive search, ... team," says Martin Farbenblum, Chairman of the board of ... years of health care administration experience from both the ...
... Jan. 27 Cannibalisation, high market complexity ... influencing the European tissue sealants and topical ... surgeries and anticipated technology innovations are continuing ... market expansion.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )New analysis from ...
... 27 Prime Companies, Inc. (Pink Sheets: ... The Company has begun receiving income from dentists paying ... The web site is now accessible to find ... , , "These are major achievements and we are pleased ...
... professionally refurbished Hill-Rom hospital beds to its extensive product ... ... Medical Equipment — named by Business First of Louisville as a ... Hill-Rom hospital beds . DRE’s extensive lineup of economically-priced hospital beds ...
... snoring. It was discovered to be an effective device to treat snoring ... years with snoring and mild obstructive sleep apnea and thankfully he is ... ... January 27, 2009 -- Sleep plays a vital role in our daily ...
... updated its peanut butter recall information portal to provide consumers with ... several consumers. Nearly 500 Americans have now been affected by the ... ... 27, 2009 -- LegalView.info, the number one resource for everything and ...
Cached Medicine News:Health News:Care to Care Announced Today That Barbara Kelman Has Joined the Organization as Senior Vice President/ Chief Operating Officer 2Health News:Ready-To-Use Products Spur the European Tissue Sealants and Topical Hemostats Markets, Says Frost & Sullivan 2Health News:Ready-To-Use Products Spur the European Tissue Sealants and Topical Hemostats Markets, Says Frost & Sullivan 3Health News:Prime Companies Revenue Stream Begins; Dentists in Every City and Town Available on Company's New Web Site 2Health News:DRE Medical Equipment Now Sells Reconditioned Hill-Rom Hospital Beds 2Health News:DRE Medical Equipment Now Sells Reconditioned Hill-Rom Hospital Beds 3Health News:Snoring Mouthpiece: Cost effective Solution For Snorers 2Health News:Snoring Mouthpiece: Cost effective Solution For Snorers 3Health News:LegalView Continues to Offer Updated News on the Recent Peanut Butter Recall Linked to Salmonella Poisonings and Several Deaths 2Health News:LegalView Continues to Offer Updated News on the Recent Peanut Butter Recall Linked to Salmonella Poisonings and Several Deaths 3
... Airial Handheld Ultrasonic Nebulizer has ... This compact, portable, and lightweight ... fast & quite treatments operating ... or DC auto adapter. , ...
With ten colors available, Spectrums line of Color-Coded Fiberoptic Light Cables makes it easy to track by department....
Lumitex® LightMat® Surgical Illuminator improves visualization in deep cavity surgery. Flexible and malleable, it attaches easily to most retractors, bringing bright, cool area lighting where...
... the exceptional performance you need at a price ... and durability youd expect from headlights priced much ... features our thinnest cable and adjusts from 90 ... when you reach for a headlight you can ...
Medicine Products: