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VSL#3® Probiotic Shown Effective in Dietary Management of Children With Irritable Bowel Syndrome
Date:8/16/2010

GAITHERSBURG, Md., Aug. 16 /PRNewswire-USNewswire/ -- New data show that VSL#3, a high-potency probiotic medical food, provides effective dietary management of children affected with irritable bowel syndrome (IBS).  

Until recently, little has been done to understand the role of probiotics in the dietary management of children with IBS.  Now, data is available showing VSL#3 as an option for children suffering from this disorder.  These data were published in the July issue of the Journal of Pediatric Gastroenterology and Nutrition.  

"There is evidence that some probiotics, such as VSL#3, have a beneficial role in the dietary management of children and teenagers suffering with IBS," said Stefano Guandalini, MD, Professor and Chief of the Section of Pediatric Gastroenterology, Hepatology and Nutrition at the University of Chicago.  "This has the potential to make a real difference for kids who suffer from pain, bloating and discomfort of IBS."

This investigation was a randomized, double-blind, placebo-controlled, crossover trial conducted in five pediatric tertiary care centers.  Patients eligible for enrollment were male and female children in the age range of 4 to 18 years, with an IBS diagnosis.  A total of 59 children completed the study.  Although placebo was beneficial in some of the parameters and in as many as half of the patients, VSL#3 was significantly superior to placebo in reaching the primary (relief of symptoms) and most secondary endpoints (abdominal pain/discomfort, abdominal bloating/gassiness and family assessment of life disruption).

About Irritable Bowel Syndrome (IBS)

IBS is a common problem in pediatrics, for which no cure is available.  This disorder is characterized most commonly by cramping, abdominal pain, bloating, constipation, and diarrhea.  IBS causes a great deal of discomfort and distress, but it does not permanently harm the i
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SOURCE Sigma-Tau Pharmaceuticals
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