VIRxSYS to Host a Web Conference to Announce Clinical Tr...(thesestudies of VRX1023 have led to the ...),Health

Institut Pasteur (Paris, France) May 2008

To commemorate the 25th anniversary of the isolation of HIV, researchers gathered at the Institut Pasteur to present cutting edge viral and clinical research. Present at this conference were Dr. Robert Gallo and Dr. Luc Montagnier, the discoverers of HIV. At the Institut Pasteur, VIRxSYS presented data from the preclinical studies of VRX1023. This innovative anti-HIV vaccine, which uses an HIV-based lentivector as vector boost, aims to reduce the impact of hyper-viremia in the first few weeks of infection. VRX1023 offers new hope for the development of an HIV-vaccine.

American Society of Gene Therapy (Boston, MA, USA) May 2008

At the American Society of Gene Therapy conference, Dr. Carl June and Dr. John Zaia presented updates on the safety of VRX496 in Phase II clinical trials. VRX496 continues to demonstrate a strong safety profile, with no adverse events associated with the treatment, which is being administered to patients using one, two, four or eight doses. The Phase II results also allowed the researchers to have a better understanding of how VRX496 works. Unlike anti-retroviral drugs, VRX496 appears to bind to the RNA of HIV, changing the genetics and biology of the virus, including the molecular diversity of HIV and the replicative fitness. In addition to these results, VIRxSYS also presented three posters on their new gene therapy vaccine, VRX1023. VRX1023 is a preclinical investigational prophylactic HIV vaccine that aims to protect but not totally sterilize individuals, thereby minimizing the likelihood of new infections.

Conference on Lentiviral Vectors (Evry, France) July 2008

VIRxSYS was invited to present its patient monitoring data at this international conference funded by the European Community. As the sponsor of the world's first clinical trial using lentiviral vector
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