Navigation Links
VIRxSYS Presents Data on HIV Vaccine at Keystone HIV Vaccine Symposia
Date:3/28/2008

HIV-Based Lentiviral vector VRX1023 Shows Promising Results

GAITHERSBURG, Md., March 28 /PRNewswire/ -- VIRxSYS Corporation will present initial scientific data for VRX1023 today at the Keystone Symposia Conference in Banff, Alberta. VRX1023 is part of a new vaccine approach -- using HIV-based lentivector as vector boost. VRX1023, an HIV antigen expressing lentiviral vector, has produced positive results in mice and in preliminary non-human primate studies. A larger, confirmatory study in Rhesus Macaques has been initiated.

"VRX1023 shows exciting promise," says Dr. Franck Lemiale, Director of Research and Development, Immunobiology for VIRxSYS. "The results from these mouse studies are very encouraging. We have seen significant long term response against HIV proteins both in terms of cellular immunity, which is mediated by T Lymphocytes, and humoral immunity, which is mediated by antibodies."

VIRxSYS takes a different approach as anti-HIV vaccine than recently publicized failed vaccines. The company is using an engineered HIV-based lentiviral vector to deliver the vaccinating antigens. In small animals, the VRX1023 lentivector has induced long-lasting cellular and humoral response against HIV. Using a DNA prime/vector boost strategy, VIRxSYS has obtained with VRX1023 greater anti-HIV immune responses than with other viral vector boost approaches currently used in the clinic, including adenoviral vectors similar to those that have been extensively tested in patients.

The ultimate goal for an anti-HIV vaccine is to suppress the impact of the initial infection, thereby significantly slowing the process of the disease. Due to the properties of the virus, a traditional total sterilizing goal may not be achievable for an anti-HIV vaccine. The next step would be to a prophylactic vaccine, which would reduce the impact of hyper-viremia in the first weeks of the infection. The aim of this vaccine is to suppress initial viremia, prevent
'/>"/>

SOURCE VIRxSYS
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference
2. EntreMed Presents Data for Phase 2 Study of MKC-1 in Metastatic Breast Cancer
3. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
4. Anadys Pharmaceuticals Presents Preclinical Results on ANA598, a Non-Nucleoside Inhibitor of the NS5B Polymerase, at the 14th International Symposium on Hepatitis C Virus and Related Viruses
5. CEL-SCI Presents Data for CEL-1000 as a Vaccine Adjuvant with Recombinant Hepatitis B Virus Protein
6. Ardea Biosciences, Inc. Presents Results of Phase 1 Studies of RDEA806, a Novel NNRTI for HIV, at 47th ICAAC
7. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
8. Wyeth Presents Phase 3 Fracture Data for Bazedoxifene, an Investigational Therapy for Osteoporosis
9. Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference
10. Surface Logix Presents Positive Phase 1 Repeat-Dose Trial Data on SLx-4090 at The 16th International Symposium on Drugs Affecting Lipid Metabolism
11. Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... Research and Markets ( ... "Endoscopy Global Market - Forecast to 2020" ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , ,The global endoscopy market ... 2019 growing at around 7.0% CAGR from 2014 ... growth are aging population, increase in cancer, diabetes, ...
(Date:4/27/2015)... 27, 2015  CytoSorbents Corporation (NASDAQ: CTSO ... its CytoSorb® extracorporeal cytokine adsorber to purify blood ... Dr. Joerg Scheier , M.D. as European ... a specialist in intensive care medicine and anesthesiology, ... in treating critically-ill patients and in the design ...
(Date:4/27/2015)... , April 27, 2015 China Jo-Jo ... " China Jo-Jo "), a leading China-based retail and ... through its online and retail pharmacies, today announced its ... Pharmacy") has signed a new sales incentive agreement with ... in China of Pfizer Inc. ...
Breaking Medicine Technology:Endoscopy Global Market - Forecast to 2020: Market is expected to reach approximately $43 billion with Johnson and Johnson, Olympus and Covidien Dominating 2Endoscopy Global Market - Forecast to 2020: Market is expected to reach approximately $43 billion with Johnson and Johnson, Olympus and Covidien Dominating 3CytoSorbents Appoints Dr. Joerg Scheier as European Medical Director 2CytoSorbents Appoints Dr. Joerg Scheier as European Medical Director 3CytoSorbents Appoints Dr. Joerg Scheier as European Medical Director 4CytoSorbents Appoints Dr. Joerg Scheier as European Medical Director 5China Jo-Jo Drugstore Signed a New Sales Incentive Agreement with Wyeth Pharmaceutical, a Subsidiary of Pfizer 2China Jo-Jo Drugstore Signed a New Sales Incentive Agreement with Wyeth Pharmaceutical, a Subsidiary of Pfizer 3China Jo-Jo Drugstore Signed a New Sales Incentive Agreement with Wyeth Pharmaceutical, a Subsidiary of Pfizer 4
(Date:4/27/2015)... 27, 2015 "Understanding Mental Disorders: Your ... 1 by American Psychiatric Publishing, a division of the ... 1pm at the National Press Club in Washington, D.C.. ... moderated by APA President Paul Summergrad, MD. Guest speakers ... the foreword to the book; Paul Gionfriddo, President and ...
(Date:4/27/2015)... Md. (PRWEB) April 27, 2015 On May ... ones will ask their social media friends around the world ... dismissed as asthma. , May 5 is World Pulmonary ... (PHA), a leader in the global PH community, will take ... or high blood pressure of the lungs. PH is an ...
(Date:4/27/2015)... According to a recent report from NIDCR ... back pain, TMJ disorders are the second most ... In addition, the report revealed that TMJ disorders affect ... an estimated 4 billion dollars annually. , These estimates ... unrelated symptoms such as headaches, neck pain, tenderness of ...
(Date:4/27/2015)... As ISO 27001 has quickly become the ... all sizes and in all industries, Pivot Point Security ... ISO 27001 certification. The information security audit firm has ... ISO 27001 certification. Pivot Point's commitment to ISO 27001 ... of Lead Implementers and Auditors the company employs (now ...
(Date:4/27/2015)... (PRWEB) April 27, 2015 Guided by ... field of patient experience and its collaboration with organizations ... The Beryl Institute identifies eight essential actions ... The Beryl Institute believes organizations and systems committed to ... Identify and support accountable leadership with committed time ...
Breaking Medicine News(10 mins):Health News:American Psychiatric Association, Patrick Kennedy To Debut New Consumer Guidebook “Understanding Mental Disorders” 2Health News:Pulmonary Hypertension Association Marks World PH Day on May 5 with a Worldwide Lifesaving Social Media Blitz 2Health News:Pulmonary Hypertension Association Marks World PH Day on May 5 with a Worldwide Lifesaving Social Media Blitz 3Health News:Dentist in Graham NC Reveals that a Jaw Disorder May Be the Cause of Chronic Headaches and Back Pain 2Health News:Six Additional New ISO 27001 Lead Implementers Certified for Pivot Point Security 2Health News:Guiding Principles for Patient Experience Excellence Identified by The Beryl Institute 2
... breakdown of retinoic acid, derived from vitamin A, is ... models of human prostate cancer, say investigators from the ... of the agent VN/14-1 resulted in up to a ... with human prostate cancer cells, reported Aakanksha Khandelwal, Ph.D., ...
... Study Supported Efficacy, Safety and Tolerability of ... 13-17 with Schizophrenia -, TOKYO and PRINCETON, ... Bristol-Myers Squibb Company (NYSE: BMY ) announced ... approved the supplemental New,Drug Application for the atypical ...
... increase 21% over the ... FARMINGTON, Conn., Nov. 6 Darwin Professional,Underwriters, Inc. ("Darwin," the ... for the third quarter ended September 30,2007. Highlights include: -- ... Third quarter gross premiums written are 5.9% ...
... ARLINGTON, Va., Nov. 6 In ... Network,s, (http://www.HealthCentral.com ) MyDiabetesCentral.com has launched ... of those with diabetes and provides,important ... this condition. The,special section, which can ...
... 6 QED International Associates Inc.,administrator for the ... portfolios, today announced that effective at the,opening of ... Ltd.,(Nasdaq: GIVN ) will replace Dade Behring ... Diagnostics Index, and Inverness Medical Innovations,(Amex: IMA ...
... Toronto, ON (November 6, 2007) Canadian researchers expect to ... network of hundreds of thousands of people who volunteer their ... complex problems. , The research team, led by Dr. ... at Princess Margaret Hospital and University Health Network, are the ...
Cached Medicine News:Health News:Drug slows prostate tumor growth by keeping vitamin A active 2Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 2Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 3Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 4Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 5Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 6Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 7Health News:U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia 8Health News:Darwin Professional Underwriters, Inc. Reports Record Net Income of $8.4 Million for the Third Quarter 2Health News:Darwin Professional Underwriters, Inc. Reports Record Net Income of $8.4 Million for the Third Quarter 3Health News:Darwin Professional Underwriters, Inc. Reports Record Net Income of $8.4 Million for the Third Quarter 4Health News:Darwin Professional Underwriters, Inc. Reports Record Net Income of $8.4 Million for the Third Quarter 5Health News:Darwin Professional Underwriters, Inc. Reports Record Net Income of $8.4 Million for the Third Quarter 6Health News:Darwin Professional Underwriters, Inc. Reports Record Net Income of $8.4 Million for the Third Quarter 7Health News:The HealthCentral Network's MyDiabetesCentral.com Promotes Awareness of Diabetes 2Health News:The HealthCentral Network's MyDiabetesCentral.com Promotes Awareness of Diabetes 3Health News:QED International Associates Announces Changes to the HealthShares(TM) Composite, and the HealthShares(TM) Diagnostics Indexes 2Health News:IBM world community grid squeezes decades of cancer research into 2 years 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: