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VIA Pharmaceuticals Completes Patient Visits in Phase 2 Acute Coronary Syndrome (ACS) Trial
Date:9/24/2008

- Top-line Data to be Released Concurrent with November 9 AHA Data

Presentations -

SAN FRANCISCO, Sept. 24 /PRNewswire-FirstCall/ -- VIA Pharmaceuticals, Inc. (Nasdaq: VIAP), a biotechnology company focused on the development of compounds for the treatment of cardiovascular disease, announced today that it has completed the last patient visit in its Phase 2 acute coronary syndrome (ACS) study, including the sub-study of patients who received an additional 3 months of treatment followed by a multi-detector computed tomography (MDCT) scan. VIA will report top-line data from the ACS trial, as well as the Phase 2 carotid endarterectomy trial (CEA), concurrent with the company's data presentations at the American Heart Association (AHA) Scientific Session 2008 on November 9.

VIA-2291 is a potent small molecule drug that targets inflammation in the blood vessel wall, a primary disease process in atherosclerosis. It is being developed as a once-daily, oral drug to potentially decrease the risk of major adverse cardiac events associated with inflammation, including heart attack and stroke.

The ACS principal study enrolled 191 patients, including more than 90 patients in the MDCT sub-study. The study is designed to establish dose and safety data in patients with ACS who have experienced a recent heart attack or unstable angina. The study includes measures of leukotrienes, biomarkers of inflammation, as well as medical imaging of the coronary vessels to evaluate the impact on plaque characteristics in a subset of patients. Patients in the study are treated once daily with one of three dose levels of VIA-2291 or placebo.

In addition to the ACS and CEA studies, VIA is conducting a third Pha
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SOURCE VIA Pharmaceuticals, Inc.
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