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VIA Pharmaceuticals Completes Enrollment in Phase 2 Acute Coronary Syndrome (ACS) Trial
Date:5/15/2008

- Top Line Data Expected soon after CEA Trial data reports in third quarter

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SAN FRANCISCO, May 15 /PRNewswire-FirstCall/ -- VIA Pharmaceuticals, Inc. (Nasdaq: VIAP), a biotechnology company focused on the development of compounds for the treatment of cardiovascular disease, announced today that it has completed patient enrollment in its acute coronary syndrome (ACS) study. The ACS study is one of three Phase 2 trials investigating VIA-2291, the company's lead product candidate in cardiovascular disease.

VIA-2291 is a potent small molecule drug that targets inflammation in the blood vessel wall, a primary disease process in atherosclerosis. It is being developed as a once-daily, oral drug to potentially decrease the risk of major adverse cardiac events (MACE) associated with inflammation, including heart attack and stroke.

"Completing enrollment in our second Phase 2 study is an important milestone for the company, and also represents the largest number of patients we have enrolled in a clinical trial to date," said Lawrence K. Cohen, PhD, chief executive officer of VIA Pharmaceuticals. "This trial will provide important data on VIA-2291's effect in the target population, patients with recent heart attack or unstable angina, and we remain on track to deliver data from this key trial later this year."

The ACS study, which enrolled 191 patients, is designed to establish dose and safety data in patients with ACS who have experienced a recent heart attack or unstable angina. The study includes measures of leukotrienes, biomarkers of inflammation, as well as medical imaging of the coronary vessels to evaluate the impact on plaque characteristics in a subset of patients. Patients i
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SOURCE VIA Pharmaceuticals, Inc.
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