Navigation Links
VAI Findings Could Aid Diagnosis and Treatment of Several Types of Kidney Cancer
Date:9/12/2008

Van Andel Institute researchers are first to associate unique DNA changes

with several types of renal cell carcinoma

GRAND RAPIDS, Mich., Sept. 12 /PRNewswire/ -- Van Andel Institute (VAI) researchers have identified unique DNA changes in each of several types of renal cell carcinoma (RCC), the most common form of kidney cancer in adults. These findings could aid in the diagnosis of these cancers since the many types of RCC are currently identified only by their appearance. Further research could identify drug targets for each type of RCC.

"There are so many subtypes of RCC, and currently they are identified by sight, which can be subjective," said VAI Distinguished Scientific Investigator Bin Tean Teh, M.D., Ph.D., whose laboratory published the recent findings in Cancer Letters. "Now we have an objective, definitive way to identify several types of RCC, which could have diagnostic and prognostic value."

The researchers found DNA changes specific to type 1 and 2 papillary RCC, sarcomatoid RCC, and clear cell RCC with and without a mutation of the VHL gene. They also found changes specific to both low-grade and high-grade clear cell carcinoma tumors. The DNA changes have to do with the number of copies of different chromosomes found in tumor cells, which researchers found was different from normal cells and among different types of RCC.

Teh said that the DNA changes they found could also lead to potential drug targets. "Each type of RCC is believed to be caused by something different," said Teh, "so ideally, different targets and therapeutic strategies should be selected for each subtype for effective treatment."

According to the American Cancer Society, RCC is the most common type of kidney cancer. In the United States, approximately 54,000 new cases of RCC are diagnosed and 13,000 deaths attributed to the disease each year.

Established by Jay and Betty Van Andel in 1996, Van Andel Institute is an ind
'/>"/>

SOURCE Van Andel Institute
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related medicine technology :

1. Findings on Bladder-Brain Link May Point to Better Treatments for Problems in Sleep, Attention
2. Halozyme Therapeutics Announces Positive Findings With Pegylated Enzyme in Prostate Cancer Models
3. FDA Updates Label for AVANDIA(R) to Include Clinical Findings Demonstrating Sustained Glycemic Control for Up to Five Years
4. Tengion Scientists Publish Key Preclinical Findings Demonstrating the Benefits of Organ Regeneration Vs. Repair
5. Study Findings Show Infection Control Intervention Helps Keep Kids in School
6. Landmark ATHENA Study Findings With Multaq(R) (dronedarone) Shows 24% Reduction In Cardiovascular Hospitalization or Death in Patients With Atrial Fibrillation
7. ISTA Pharmaceuticals Announces New Phase III Clinical Findings to Support Bepreve NDA Filing
8. ACORN Presents Findings of Collaborative Metastatic Colorectal Cancer Research
9. Halozyme Therapeutics Presents Findings on Combinations of rHuPH20 Enzyme With Bisphosphonates at the American Association for Cancer Research Conference
10. Mayo Clinic Proceedings Contributors Highlight Research Findings About Cardiovascular Benefits Associated With Omega-3 Fatty Acids
11. Recent Findings from the Framingham Offspring Study Show Low Numbers of LDL Particles (LDL-P) by NMR are Associated With Fewer Heart Disease Related Events than Equivalently Low Levels of LDL Cholesterol (LDL-C).(1)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... 20, 2013  B. Braun Medical Inc. (B.Braun) ... safety with products, services and education focused on ... innovative Outlook® 400ES and Space Infusion Systems, and ... the American Association of Critical-Care Nurses (AACN) National ... Boston Convention Center. ...
(Date:5/20/2013)... 2013 /PRNewswire-iReach/ -- It is no secret that Americans have ... or obese gyms and supplement companies are in line to ... primarily related to dietary issues and a lack of physical ... a glandular problem or even a vitamin deficiency. ... is a lack of vitamin b12 . The vitamin ...
(Date:5/20/2013)... May 20, 2013 /PRNewswire-iReach/ -- Today at American ... Christine Ginocchio discussed Specific Technologies ... rapid identification of microorganisms producing bloodstream infection. Dr. ... of the Division of Infectious Disease Diagnostics at ... not-for-profit, non-sectarian health system. (Photo: ...
Breaking Medicine Technology:B. Braun Committed To Improving Patient Safety 2USB12Shots.com Discusses the Possibility of B12 Shots for Weight Loss 2Specific Technologies Bloodstream Infection Identification Solutions Discussed at the American Society for Microbiology Conference by Award Lecturer Christine Ginocchio 2Specific Technologies Bloodstream Infection Identification Solutions Discussed at the American Society for Microbiology Conference by Award Lecturer Christine Ginocchio 3
... Lines for Therapeutic ... Cloning, ... to report, and painstakingly document, the cloning of a,human embryo using donated ... study was published online today by the journal "Stem,Cells.", (Logo: ...
... Cataract surgery involves,removing a clouded natural lens from ... While the operation itself hasn,t changed much over recent,years, ... newer lenses,is their ability to reduce the need for ... Medical School., The Aging Eye: Preventing and Treating ...
Cached Medicine Technology:Study Reports Successful Cloning of Human Embryo Using Adult DNA 2Study Reports Successful Cloning of Human Embryo Using Adult DNA 3New Implantable Lenses Can Reduce the Need for Glasses After Cataract Surgery 2
(Date:5/20/2013)... The India Network Foundation, a ... insurance, announces a new pre-existing condition coverage plan: ... the years, India Network members have requested a ... maximums, and duration. The Platinum Comprehensive Plan is ... the valuable coverage and benefits of a PPO ...
(Date:5/20/2013)... This week has been dedicated as National Dog ... 25th) is an awareness campaign designated to help prevent dog ... owners to properly train their pets, and educate children on ... lawyers at Buckfire & Buckfire, P.C. represent victims of ... personal injury law firm is a large advocate of this ...
(Date:5/20/2013)... 20, 2013 When people have ... always to become a celebrity. New Jersey governor ... ABC News report (“Chris Christie Says Lap Band ... that the surgery was not done so that ... celebrity status as a former lap band patient. ...
(Date:5/20/2013)... May 20, 2013 Dr. Robert Mokbel ... and trained to use the Laser Assisted New Attachment ... treat patients with gum disease. LANAP may help many ... to gum disease restore the jawbone support necessary to ... buildup of plaque and tartar in the mouth. Daily ...
(Date:5/20/2013)... (PRWEB) May 20, 2013 Mombo from ... first national conference of the US Lactation Consultant Association ... experts including nurses, doctors and other health professionals. ... aimed at helping lactation professionals discover and learn about ... one of the most popular nursing pillows, which new ...
Breaking Medicine News(10 mins):Health News:Indian Network announces Platinum Comprehensive Visitor Health Insurance Plan with Pre-existing Condition Choices for Visitors on Short Term Trip to the United States 2Health News:Indian Network announces Platinum Comprehensive Visitor Health Insurance Plan with Pre-existing Condition Choices for Visitors on Short Term Trip to the United States 3Health News:Buckfire & Buckfire, P.C. Dog Bite Lawyers in Michigan Discuss National Dog Bite Prevention Week 2Health News:The Lap Band Center: Dr. Atul Madan Applauds Chris Christie's Dedication to Family and Loss of 30 Pounds After Lap Band Surgery 2Health News:The Lap Band Center: Dr. Atul Madan Applauds Chris Christie's Dedication to Family and Loss of 30 Pounds After Lap Band Surgery 3Health News:Fountain Valley, Ca Gum Disease Patients with Missing Teeth Can Now Receive Laser Gum Surgery from Dr. Robert Mokbel for Success with Dental Implants 2Health News:Comfort & Harmony™ Exhibited mombo™ Nursing Pillow at USLCA’s First Inaugural Conference 2
... Blood America, Inc. (OTC Bulletin Board: CBAI), the umbilical ... focused on bringing the life saving potential of stem ... announce that its shareholders at a Special Meeting on ... increase the number of authorized (not outstanding) common shares. ...
... Education Solution Streamlines Student Evaluations and Consolidates Scheduling and Curriculum ... ... March 25, 2009 -- one45 Software, a leading provider of ... Cytiva Software Inc. (CRX:TSX.V), announced today the selection of its ...
... produces its own direct mail concept boxes to draw medical device packagers ... ... March 25, 2009 -- To announce their new clean room production capabilities, ... devices industry. The well-known custom thermoformer of trays, clamshells and other plastic ...
... Professional is less invasive than blood tests at detecting lead levels in ... ... Until now, determining a person,s lead exposure has been an invasive procedure ... Professional, a new saliva-based lead test that screens for lead ...
... one African-American student of high achievement. Ricky Williams is the First ... ... 2009 - Acupuncture & Massage College has established a new scholarship. ... of high achievement. The first recipient will be Ricky Williams, Miami ...
... of the Program in Clinical Effectiveness (PCE), which has ... 1986, have achieved significant success in receiving grant support ... funders, along with other accomplishments considered key to establishing ... a joint program of Brigham and Women,s Hospital ...
Cached Medicine News:Health News:Texas A&M Health Science Center College of Medicine Selects one45 Software's Healthcare Education Suite 2Health News:Texas A&M Health Science Center College of Medicine Selects one45 Software's Healthcare Education Suite 3Health News:Texas A&M Health Science Center College of Medicine Selects one45 Software's Healthcare Education Suite 4Health News:Tray-Pak Direct Mailer Garners 21% Response, Design Award 2Health News:The First Oral Based Lead Test, LeadConfirm Professional, Makes Getting The Lead Out Easier 2Health News:The First Oral Based Lead Test, LeadConfirm Professional, Makes Getting The Lead Out Easier 3Health News:The First Oral Based Lead Test, LeadConfirm Professional, Makes Getting The Lead Out Easier 4Health News:Acupuncture & Massage College Announces Ricky William's Scholarship 2Health News:Acupuncture & Massage College Announces Ricky William's Scholarship 3Health News:Intensive summer program helps physicians build clinical research careers 2Health News:Intensive summer program helps physicians build clinical research careers 3
... electrophoretic transfer apparatus incorporating state-of-the-art plate electrodes ... design allows for a very close positioning ... a low voltage power source such as ... in volts/cm. The result is exceptionally rapid ...
The HEP-1 system accommodates mini to full size gels with a transfer area of 20cmWx 20cmL, designed specifically for the transfer from polyacrylamide or agarose gels....
... from agarose gels to hybridization membranes in ... and efficiency of transfer by allowing high ... of an integrated system allowing electrophoresis, gel ... hours, versus 29 hours required for conventional ...
Trans-Blot Plus Gel/Cassette Assembly Tray...
Medicine Products: