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VAI Finding Could Lead to New Drugs for Anxiety, Depression
Date:10/15/2008

ture, researchers had to crystallize the hormone and receptor in these different scenarios, a process similar to letting salty water evaporate to form salt crystals but much more difficult. The lab used a unique method to do this that they recently developed to determine the structure of the parathyroid hormone (PTH) receptor, used to treat osteoporosis. PTH and CRF receptors are in the same family of proteins.

"There are many therapeutically important receptors in the same family as CRF and PTH," said Xu, "and there is a good chance we may be able to apply our crystallizing method to even more members of this family going forward."

Established by Jay and Betty Van Andel in 1996, Van Andel Institute is an independent research organization dedicated to preserving, enhancing and expanding the frontiers of medical science, and to achieving excellence in education by probing fundamental issues of education and the learning process.

http://www.vai.org


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