Navigation Links
Update: Clinical Trial Establishes Catheter-based Aortic Valve Replacement As New Standard of Care for Patients Who Cannot Undergo Surgery
Date:9/23/2010

ves, which regulate blood flow from the heart into the aorta, can fall victim, typically with age and the onset of cardiovascular disease, to stenosis (failure to open) and insufficiency (which leads blood to flow in the wrong direction back into the heart). Aortic stenosis results in a poor quality of life and a high rate of death, approximately 50 percent, in the first two to three years after diagnosis without surgical intervention. Approximately 300,000 Americans suffer from severe aortic stenosis.

In clinical practice, at least 30 percent of patients with severe symptomatic aortic stenosis do not undergo surgery for replacement of the aortic valve because of advanced age, left ventricular dysfunction, or the presence of multiple coexisting conditions.

The replacement valve used in the PARTNER trial is made of pericardial tissue leaflets hand-sewn onto a metal frame and implanted via a catheter into the left ventricle. It is then positioned inside the patient's existing valve using a balloon to deploy the frame, which holds the valve replacement in place. The procedure is performed on a beating heart, without the need for cardiopulmonary bypass and its associated risks.

The transcatheter valve procedure takes about 90 minutes, compared with four to six hours for open-heart surgery. In open-heart surgery, the surgeon cuts through the breastbone, stops the heart, removes the valve, and replaces it. Open-heart surgery can require a two- to three-month recovery period, compared with only a few days for the transcatheter approach.

The multicenter PARTNER trial, which has more than 1,000 patients, began in 2007 and will be completed in 2014. The results reported today reflect only the cohort of patients who are not considered candidates for surgery. The other arm of the trial, which compares transcatheter valves with surgically implanted valves, is ongoing. The executive committee of the trial includes two academic co-principal investigat
'/>"/>

SOURCE NewYork-Presbyterian Hospital/Columbia University Medical Center
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. UPDATE: China PharmaHub Corp. Introduces a Magic Bullet Liver Cancer Therapy to China, Hong Kong, Taiwan, Macau, Singapore, Malaysia, and Bangladesh
2. Update: International HIV/AIDS Partnership Wins Two Awards for Supply Chain Excellence
3. UPDATE: FDA Issues 22 Warning Letters to Web site Operators
4. UPDATE: US Oncology Research Network Participates in Phase III Follow-up Study to BiPars Investigational Cancer Drug BSI-201
5. ELADUR(TM) Development Update: DURECT Receives Orphan Drug Designation for Bupivacaine for Post-Herpetic Neuralgia
6. UPDATE: Infant Primates Given Vaccines on U.S. Childrens Immunization Schedule Develop Behavioral Symptoms of Autism
7. UPDATE: Nebivolol Lowers Blood Pressure in African Americans With Stage I-II Hypertension as Demonstrated in a Study Published in the Journal of Clinical Hypertension
8. UPDATE: New Report by Pediatricians Finds Gaps in Preparing to Protect Kids From Pandemic Flu, Offers Recommendations
9. UPDATE: Nile Therapeutics Announces Positive Phase 1a Results of CD-NP, a Selective NPR-B Agonist in Clinical Development for the Treatment of Heart Failure
10. Clinical Trial Establishes Catheter-Based Aortic Valve Replacement as New Standard of Care for Patients Who Cannot Undergo Surgery
11. Abbotts Fully Bioresorbable Vascular Scaffold Technology Continues to Demonstrate Strong Clinical Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... WESTFORD, Mass. , July 30, 2014 ... in laser- and light-based aesthetic treatments for non-invasive and minimally ... promoted Executive Vice President, Chief Operating Officer and Chief Financial ... Company, effective August 1, 2014.  Baker, 53, will continue to ... from Michael Davin , who remains Chairman and Chief ...
(Date:7/30/2014)... and SAN DIEGO , July 30, 2014 ... ARNA ) announced today that an article based on post-hoc ... entitled, "Early Weight Loss While on Lorcaserin, Diet, and Exercise ... published in the online issue of Obesity , the ... of these analyses was to identify whether there is an ...
(Date:7/30/2014)... /PRNewswire-iReach/ -- This is a professional and in-depth ... (CAS 9041-08-1) & calcium (CAS 37270-89-6) industry. The ... sodium (CAS 9041-08-1) & calcium (CAS 37270-89-6) including ... then explores global and China,s top manufacturers of ... listing their product specification, capacity, production value, cost, ...
Breaking Medicine Technology:Cynosure Appoints Chief Operating Officer and Chief Financial Officer Timothy W. Baker as President 2Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity 2Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity 3Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity 4Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity 5Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity 6Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity 7Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 2Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 3Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 4Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 5
... Jude scientists, findings in ataxia telangiectasia-like disease ... the links between brain disease and cancer ... Jan. 14 Scientists at ... apart the biological details distinguishing two related ...
... VALENCIA, Calif., Jan. 13 MannKind Corporation ... of its trial to demonstrate equivalence of its commercial ... used in clinical trials to deliver AFRESA(TM), MannKind,s ultra ... trials. Study 138 - Bioequivalence of Clinical and ...
Cached Medicine Technology:Study Shows How Defective DNA Repair Triggers Two Neurological Diseases 2Study Shows How Defective DNA Repair Triggers Two Neurological Diseases 3MannKind Reports Successful Completion of Device Bioequivalence Trial 2MannKind Reports Successful Completion of Device Bioequivalence Trial 3
(Date:7/30/2014)... (PRWEB) July 30, 2014 The family ... bleeding has filed a Xarelto lawsuit ( http://www.xareltolawsuitcenter.com/ ... thinner, Bernstein Liebhard LLP reports. According to the complaint, ... District of Vermont on July 25th, the decedent had ... suffered an irreversible brain bleed that ultimately led to ...
(Date:7/30/2014)... Hawley, Pennsylvania (PRWEB) July 30, 2014 ... and have contributed over $8,500 to ensure its protection. ... Resort, presents a check to the Delaware Highlands Conservancy ... Partnership program. The small $2-per-stay donations add up fast, ... future of the Upper Delaware River Region. , The ...
(Date:7/30/2014)... July 30, 2014 (HealthDay News) -- Some obese people ... the reward centers in their brains when they see ... how this mutation triggers feelings of pleasure and gratification ... help improve strategies designed to prevent overeating, the scientists ... obese. Obesity is typically caused by a combination ...
(Date:7/30/2014)... KY (PRWEB) July 30, 2014 DRE ... pleased to announce the launch of its Medical ... online resource for medical professionals and equipment vendors. , ... shows and conventions in the United States and around ... the calendar, and that number is always growing. , ...
(Date:7/30/2014)... ... ... ... , UCLA researchers interviewed people ... published this week in the peer-reviewed journal Quality of Life Research , a UCLA team led by Dr. Brennan Spiegel interviewed ...
Breaking Medicine News(10 mins):Health News:Xarelto Lawsuit Alleges Man’s Death from Uncontrollable Brain Bleeding Was Caused by Xarelto, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit Alleges Man’s Death from Uncontrollable Brain Bleeding Was Caused by Xarelto, Bernstein Liebhard LLP Reports 3Health News:Pocono Mountain Resort Guests Contribute Over $8500 to Protect Land in 6 Short Months 2Health News:Gene Mutation May Make Food More Tempting 2Health News:DRE Launches Online Interactive Medical Trade Show Calendar 2Health News:Diverticulitis patients reveal psychological, physical symptoms long after acute attacks 2Health News:Diverticulitis patients reveal psychological, physical symptoms long after acute attacks 3
... Increased 74.0% to $59.0 Million in 2Q08 -- ... Increased 43.4% to $13.9 Million -- ... EPS $0.15 --, NEW YORK, Aug. 11 /Xinhua-PRNewswire-FirstCall/ -- ... dedicated to,improving health through the development, manufacture and commercialization,of a ...
... of $17.9 Million Treatment Tip and Other Consumables Revenue Up ... ... Thermage, Inc.,(Nasdaq: THRM ), a leader in non-invasive tissue tightening ... ended,June 30, 2008., Revenue for the second quarter of 2008 totaled ...
... may provide context for tumor formation, new treatments ... more about normal cells that give rise to cancer ... according to Duke University Medical Center researchers who identified ... "Identifying the specific, normal cells that cancer come from ...
... more common, study finds , , MONDAY, Aug. 11 ... adults don,t have the 20/20 vision physicians consider ... an irregular corneal curve known as astigmatism, a ... that such common eye-focus problems -- collectively known ...
... fewer disabilities, study finds , , MONDAY, Aug. 11 (HealthDay News) ... -- and even the creeping ravages of time -- at ... found that older runners live longer and suffer fewer disabilities ... to a variety of aerobic exercises, including walking, said the ...
... (August 11, 2008) Scientists from the University of ... people who develop Alzheimer,s disease may show signs of ... educational achievement. Their research appears online this month in ... , Participants in the Nun Study were studied to ...
Cached Medicine News:Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 2Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 3Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 4Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 5Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 6Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 7Health News:American Oriental Bioengineering Reports Second Quarter 2008 Financial Results 8Health News:Thermage Announces Second Quarter 2008 Financial Results 2Health News:Thermage Announces Second Quarter 2008 Financial Results 3Health News:Thermage Announces Second Quarter 2008 Financial Results 4Health News:Thermage Announces Second Quarter 2008 Financial Results 5Health News:Thermage Announces Second Quarter 2008 Financial Results 6Health News:Thermage Announces Second Quarter 2008 Financial Results 7Health News:Thermage Announces Second Quarter 2008 Financial Results 8Health News:Thermage Announces Second Quarter 2008 Financial Results 9Health News:Researchers Hunt Normal Cells That Give Rise to Cancer 2Health News:Half of U.S. Adults Lack 20/20 Vision 2Health News:Half of U.S. Adults Lack 20/20 Vision 3Health News:Run for Your Life 2Health News:Run for Your Life 3Health News:Signs of Alzheimer's disease may be present decades before diagnosis 2
The autoclavable, aluminum needle box is designed to store loaded needles and help protect personnel from exposure. Each shield consists of an aluminum box with faceplate to match the grid pattern th...
... The TheraSeed® Pd-103 implant is a combination ... remarkable visibility that makes TheraSeed® treatment an ... can be confident that every TheraSeed® implant ... services which is required by clinicians who ...
... Bard BrachyStar® Needle is designed to help ... and clinically effective brachytherapy procedure. All needles ... tips and polished surfaces for smooth entry ... configurations and sizes assures an ideal match ...
... is designed to help you achieve one ... brachytherapy procedure. All needles are engineered for ... surfaces for smooth entry and exit. A ... assures an ideal match with procedural needs ...
Medicine Products: