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Up to Sixty Percent of Surveyed U.S. Managed Care Organization Directors Expect to Cover Key Emerging Therapies for Parkinson's Disease on Their Largest Commercial Plan
Date:8/19/2013

BURLINGTON, Mass., Aug. 19, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that up to 60 percent of surveyed U.S. managed care organization (MCO) pharmacy and medical directors expect to reimburse several late-stage emerging Parkinson's disease (PD) therapies on their largest risk-based commercial plan. Profiled in the report are four emerging agents that target primarily underserved populations, including IPX-066 (Impax Laboratories' Rytary), an extended-release reformulation of levodopa (multiple brands, generics), the mainstay of PD treatment, Acadia Pharmaceuticals' pimavanserin for PD-related psychotic symptoms, Novartis's mavoglurant (AFQ-056) for dyskinesias and Newron Pharmaceuticals/Zambon Pharma/Meiji Seika Pharma's MAO-B inhibitor safinamide.

The U.S. Physician and Payer Forum report entitled The Complex Parkinson's Disease Treatment Algorithm: U.S. Physician and Payer Perspectives on the Current and Future Landscape finds that formulary exclusion can be common for current PD brands, with at least one-third of MCO respondents indicating that their largest commercial plans and Medicare prescription drug plans exclude or block key brands from coverage. The most recent market entrant, UCB's dopamine agonist Neupro (rotigotine), is similarly covered, despite offering once-daily dosing and unique transdermal delivery. Nevertheless, when reimbursing key current brands, surveyed payers largely include such agents on tiers 2 and 3 (i.e. commonly preferred and non-preferred brands, respectively), and generally expect similar tier placement for the emerging agents profiled if priced at approximately $10 per day or higher.

The report also finds that surveyed neurologists estimate the eligible patient pool for emerging products querie
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SOURCE Decision Resources
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