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University of Pennsylvania joins Actinium Pharmaceuticals' Multicenter Actimab-A Trial
Date:1/17/2013

NEW YORK, Jan. 17, 2013 /PRNewswire/ -- Actinium Pharmaceuticals, Inc. (API), a public biopharmaceutical company (OTC BB: CTVN) that develops innovative targeted payload immunotherapeutics, announced that the University of Pennsylvania Health System in Philadelphia, PA has joined the Company's ongoing Phase I/II trial in newly diagnosed elderly patients with acute myeloid leukemia (AML).  The trial is designed to establish the safety and efficacy of API's drug Actimab-A in AML patients over the age of 60.  Actimab-A treatment consists of the isotope Actinium 225 attached to the anti-CD33 monoclonal antibody lintuzumab (HuM195). 

"We are pleased to welcome UPenn as an additional site in our multicenter trial, another clear validation point as we continue to make solid progress," said Jack Talley , CEO of Actinium Pharmaceuticals.  "Five of the leading leukemia treatment centers that have been setting the pace in new approaches to AML have now expressed their readiness to be our partners in bringing the benefits of alpha particle immunotherapy technology to patients in need of new approaches. We look forward to building on this momentum throughout the year."

The University of Pennsylvania Health System is the fifth center to sign a clinical trial agreement with Actinium Pharmaceuticals, following Memorial Sloan Kettering Cancer Center (MSKCC) in New York, NY, Fred Hutchinson Cancer Research Center (FHCRC) in Seattle, WA, MD Anderson Cancer Center in Houston, TX and Johns Hopkins in Baltimore, MD.

The phase I/II multi-center Actimab study builds on the previous phase I/II Bismab-A study with a less potent bismuth-213 (Bi-213) isotope and an earlier Actimab-A phase 1 study (where only a single dose of Actimab was administered).  The Phase
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SOURCE Actinium Pharmaceuticals, Inc.
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