Navigation Links
University of Luebeck Joins GeneGo's Metaminer Cardiac Project
Date:7/20/2010

ST JOSEPH, Mich., July 20, /PRNewswire/ -- GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that Dr. Salah Mohamed in Department of Cardio and Thoracic Vascular Surgery at the University of Luebeck and his team will be part of the Metaminer Cardiac Partnership. Dr. Mohamed is published within 6 different reputed Scientific American Journals in connection with Biomarker Discovery work performed for the American Heart Association.

Mohamed and colleagues theorized that the cause of acute aortic dissection lay in the interaction of other proteins with the protein MS FBN1.  That protein is encoded by a mutated gene linked to Marfan syndrome. Researchers found 88 genes in the tissue of all 19 acute aortic dissection patients who had gene expression — the process that converts a gene's encoded information into a protein —significantly different from the same genes in the Marfan patients and the control group. Further investigation revealed that the MS FBN1 protein interacted directly with the proteins of four of the 88 genes — fibulin 1 (FBLN1), fibulin 2 (FBLN2), Decorin (DCN) and microfibrillar associated protein 5 (MFAPS5).

"Interestingly, one of these four proteins is considered as a candidate in the development of Marfan syndrome," Mohamed said. "The study was also aimed at the future development of a clinical test for monitoring patients with a high risk of acute aortic dissection. Most acute aortic dissection patients do not have a known connective tissue disorder. The identification of the four genes could be a starting point to develop a diagnostic tool, and we plan to utilize GeneGo's tools to further this study."

"Dr. Mohamed and his group are going to bring a lot of domain knowledge to the MetaMiner Cardiac Project which is essential to its success," said Julie Bryant, VP Business Development of GeneGo. "Cardiac disease reconstruction pathway maps are unique to GeneGo and we have been pioneers in this field.  We are also looking for more Pharmaceutical members with domain expertise."

About GeneGo, Inc.

GeneGo, Inc. develops systems biology technology such as compound based pathway analysis, cheminformatics & bioinformatics software for life science research. The original computational MetaDiscovery(TM) platform allows an integration and expert analysis of different kinds of experimental data (mRNA expression, proteomics, metabolomics, microRNA assays and other phenotypic data) and relevant bioactive chemistry (metabolites, drugs, other xenobiotics) within the framework of curated biological pathways and networks. GeneGo's flagship product, MetaCore 6.3(TM), assists pharmaceutical scientists in the areas of target selection and validation, data mining in biology, identification of biomarkers for disease states and toxicology. The second product, MetaDrug 6.3(TM) is designed for prediction of human metabolism, toxicity and biological effects for novel small molecules compounds. MetaBase(TM) represents the knowledge base for MetaCore.

For more information, please visit the company's web site at www.genego.com.


'/>"/>
SOURCE GeneGo, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. University HealthSystem Consortium Awards Single-Source Agreement to Ascent for Medical Device Reprocessing Services
2. Biospherics Acquires Global Patent Rights from University of Kentucky Research Foundation to Develop Tagatose as a Trigylcerides Therapy
3. Ethicon Endo-Surgery Extends Research Partnership with $13.5 Million Grant to University of Cincinnati
4. University of Michigan Wolverine Venture Fund Invests in Delphinus Medical Technologies
5. John DeVincenzo, MD, at the University of Tennessee Health Science Center Discovers First Evidence that RNA-interference Drugs Reduce Human Disease
6. University HealthSystem Consortium Selects Centurion Service Group for Equipment and Asset Liquidation Services
7. Binder Biomedical, Inc. Announces the Release of the X-GRAFT(TM) Interspinous Device, as Part of Their QUANTUM(TM) Line of Spinal Allograft Devices, Manufactured at the University of Miami Tissue Bank
8. Karolinska University Hospital Acquires Leksell Gamma Knife Perfexion to Expand Radiosurgery Versatility, Efficiency in Brain Cancer Therapy
9. 2nd Annual Orthopedic Design & Technology Forum Returns April 28 to the FedEx Institute of Technology, University of Memphis
10. TechniScan Launches 3-D Breast Ultrasound Clinical Study in Freiburg University
11. IVF FLORIDA Reproductive Associates Partners with The University of Miami School of Medicine and Jackson Memorial Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... , Sept. 22, 2017  As the latest ... Senators Bill Cassidy (R-LA) and Lindsey ... notes that the medical device industry is in an ... device tax, the 2.3% excise tax on medical device ... they also want covered patients, increased visits and hospital ...
(Date:9/18/2017)... , Sept. 18, 2017  PMD Healthcare of ... Pharmacy of Kalamazoo, Mich. , have ... service that expedites and streamlines patient and provider access ... 2.0, and wellness management services.  ... used to measure lung function for a variety of ...
(Date:9/12/2017)... , Sept. 12, 2017  Consumer reviews on the independent ... as the number one company for hearing aids, ranking it ... fifteen other brands. ... Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high performance, ...
Breaking Medicine Technology:
(Date:10/13/2017)... QUEENS, N.Y (PRWEB) , ... October 13, 2017 , ... ... recently became a member of ElderCounsel, a national organization of elder law and special ... constantly changing laws and rules. It also provides a forum to network with elder ...
(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and ... of published author, William Nowers. Captain Nowers and his wife, Millie, have six ... years in the Navy. Following his career as a naval aviator and carrier ...
(Date:10/12/2017)... ... ... IsoComforter, Inc. ( https://isocomforter.com ), one of the Nation’s premier ... of the shoulder pad. The shoulder pad provides optimal support and full contact ... using cold therapy. By utilizing ice and water that is circulated from an insulated ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare ... Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during ... , The annual award competition recognizes editorial and design excellence across a range of ...
Breaking Medicine News(10 mins):