Navigation Links
United States Patent Office Issues Patent Covering the Approved Administration of Kuvan With Food
Date:11/5/2009

NOVATO, Calif., Nov. 5 /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) announced today that the United States Patent and Trademark Office has issued a patent covering the approved administration of Kuvan® (sapropterin dihydrochloride) with food for the treatment of phenylketonuria (PKU). The patent expires in 2024.

"We believe that the food effect patent, based on the discovery that food increases the bioavailability of Kuvan, along with our patents for once daily dosing and stable tablet formulation, will create significant barriers to therapeutically equivalent generic competition from entering the market for approximately ten years beyond orphan drug exclusivity," said Jean-Jacques Bienaime, Chief Executive Officer of BioMarin. "We remain committed to serving the PKU community with initiatives such as implementation of an outcomes study in the second quarter of next year and the ongoing development of a blood Phe monitor. We also look forward to results from various investigator-sponsored trials that, if positive, will strengthen the value proposition for the use of Kuvan."

About Kuvan

Kuvan® (sapropterin dihydrochloride) Tablets are indicated in the United States to reduce blood phenylalanine (Phe) levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive phenylketonuria (PKU). Kuvan is to be used in conjunction with a Phe-restricted diet. The active ingredient in Kuvan, sapropterin dihydrochloride, is the synthetic form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe.

Kuvan has received orphan drug designation from both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA). Kuvan has
'/>"/>

SOURCE BioMarin Pharmaceutical Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
2. R-CALF United Stockgrowers of America: Fighting for the U.S. Cattle Producer
3. United States, Canada and Mexico Agree to Mutual Assistance During Public Health Emergencies
4. Parker Waichman Alonso LLP and Affiliated Lawfirms Have Filed a Class Action Lawsuit in the United States District Court for the Eastern District of New York Against Merck & Co., Inc. and Schering-Plough Corporation
5. Peptimmune Announces Grant of United States Patent for PI-2301 Peptide Copolymer for Multiple Sclerosis
6. A First-Line Therapy for Renal Cell Carcinoma that can Increase Overall Survival when Compared with Sutent Would Earn a Higher Patient Share in the United States Than in Europe
7. American Oriental Bioengineering to Initiate a Phase One Clinical Trial in the United States of AOBO-001 Oral Capsule
8. Premier Research Expands its Medical Device Operations to the United States
9. Watson Announces United States Availability of RAPAFLO(TM) (silodosin), a Novel New Treatment in Benign Prostatic Hyperplasia (BPH)
10. United States Patent and Trademark Office Publishes Stemedicas Patent Application for the Treatment of Diabetic Retinopathy
11. EMD Serono Submits Application for Cladribine Tablets as a Potential Oral Short-Course Multiple Sclerosis Therapy in the United States
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... LUTHERVILLE, Md. , Aug. 20, 2014 /PRNewswire/ ... today lauded the latest results achieved by the ... known as the National Precursor Log Exchange (NPLEx), ... enforcement officials track down methamphetamine offenders and make ... in Michigan blocked the ...
(Date:8/20/2014)... YORK , Aug. 20, 2014 ... is available in its catalogue: The ... IVD Industry http://www.reportlinker.com/p01618927/The-Impact-of-Healthcare-Reform-PPACA-On-the-US-IVD-Industry.html ... Act" (H.R. 3590) is complex legislation that affects ... of its provisions are beginning to take effect ...
(Date:8/20/2014)... , Aug. 20, 2014 Torrance ... be using advanced, ventilator technology from Covidien to ... care for patients. The acute ... naturally, compared to conventional mechanical ventilation, and help ... as possible. Patients on mechanical ventilation are often ...
Breaking Medicine Technology:Michigan's Stop-Sale System Achieves Significant Results In Battle Against Meth 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 3The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 4The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 5The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 6Torrance Memorial Medical Center Acquires Advanced Ventilator Technology to Enhance Patient Care 2
(Date:8/21/2014)... 2014 mynt welcomes industry leaders Rob ... join its growing company. Since its pre-launch in April, ... sales and continues to gain momentum leading up to ... and Tiffanie came into network marketing by chance. Tiffanie ... of network marketing companies. Tiffanie needed help at one ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 According ... by Application (Biodegradable polymer, Food & Beverage, Personal ... Application (Packaging, Agriculture, Automobile, Electronics, Textile) & Geography ... the lactic acid and polylactic acid markets and ... of each market, based on their sub-segments, in ...
(Date:8/21/2014)... San Luis Obispo, CA (PRWEB) August 21, 2014 ... July/August edition of Current Pedorthics, a bi-monthly publication of the ... the field of pedorthics. , Bunion Bootie ... as an alternative solution for bunion sufferers and their pain. ... be worn in nearly any shoe to eliminate the friction ...
(Date:8/21/2014)... 2014 While golfing in Scotland and ... to stay focused on his game due to the ... whine, slapping and continual need to spray insect repellent ... stay protected from insects while golfing. He ultimately found ... Financial Services/Investment Banking Industry, decided to change direction and ...
(Date:8/21/2014)... August 21, 2014 Atlantic Information Services, ... ACO Business News and The AIS Report on Blue ... Blue Cross Blue Shield Association or its member companies) ... latest report in AIS’s Management Insight Series. Bundled ... studies of two insurers — Horizon Healthcare Services, Inc. ...
Breaking Medicine News(10 mins):Health News:Industry Leaders Rob and Tiffanie Moffitt Join mynt 2Health News:Lactic Acid Market Worth $3,577.5 Million & Polylactic Acid Market Worth $4,840.1 Million by 2019 – New Report 2Health News:Lactic Acid Market Worth $3,577.5 Million & Polylactic Acid Market Worth $4,840.1 Million by 2019 – New Report 3Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 3Health News:Financial VP Fights Pesky Bugs with Launch of Biteback Sports Insect Shield® Golf Apparel 2Health News:New AIS Report Highlights Two Case Studies of Bundled Payment Models 2
... , - Tobacco use is the single most preventable cause of death ... 400,000 Americans die each year from tobacco-related disease , ... , illegal drugs, car crashes, fires, murders, and suicides combined. ... seconds . , , HOUSTON, June 23 DaretoQuit.com is ...
... earlier this month by Harvard Law School, Harvard Medical ... bills are involved in more than 60 percent of US ... more than 75 percent of these families reported having health ... wake of these startling increases and the current recession, The ...
... At Risk with Atlantic Hurricane Predictions; Are Their Medical Records ... With hurricane season upon us, more than 35 million Americans ... their medical records. According to the National Ocean and ... having nine to 14 named storms, of which four to ...
... ... provides up to 99% accuracy right out of the box. The Nuance Dragon Medical 10.1 ... the ideal chance for existing Dragon Medical users to upgrade and become even more efficient. ... Austin, Texas (PRWEB) June ...
... June 23 /PRNewswire-Asia/ -- Wan (Corporate Services) Ltd., the,sole agent of Perrier ... level of Perrier. , ... We strongly believe the Consumer Council Findings is not correct. ... mg/L of Nitrite in Perrier is,not correct. , ...
... tumor growth , MONDAY, June 22 (HealthDay News) -- A ... of cancer and could potentially be harnessed as a cancer ... for inhibiting or treating metastasis -- the migration of cancer ... the body. Metastasis is one of the leading causes of ...
Cached Medicine News:Health News:STOP SMOKING ONLINE: Houston Psychologists Develop Groundbreaking, Interactive Stop Smoking Program 2Health News:The Wellness Community Launches National Education Program Addressing the Cost of Cancer Care 2Health News:The Wellness Community Launches National Education Program Addressing the Cost of Cancer Care 3Health News:Consumers Encouraged to Add Personal Health Records (PHR) to Hurricane Preparedness Checklist 2Health News:Consumers Encouraged to Add Personal Health Records (PHR) to Hurricane Preparedness Checklist 3Health News:The New Dragon Medical 10.1 is Now Available 2Health News:The New Dragon Medical 10.1 is Now Available 3Health News:Perrier Clarifies the NITRITE Level in Consumer Council Findings 2Health News:Lab Study Finds Protein That May Inhibit Cancer Spread 2
... the parafollicular C-cells of the thyroid gland ... major action of calcitonin is to lower ... resulting in decreased mobilization of calcium from ... in conditions associated with high levels of ...
Validated by decades of research and clinical experience, HFA is the accepted standard of care in glaucoma diagnosis and management. With HFA you can feel confident you're providing the best possible...
Erbium Laser with Sapphire Erbium Handpiece for Dermatological and Cosmetic Surgery...
... The Bio-Optics LSM-12000 is a new High ... new tool in anterior segment diagnostics and ... to operate, easy to maintain, and very ... the only High Magnification Slit-Lamp Biomicroscope available ...
Medicine Products: