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Unigene Laboratories Granted US Patent for Peptide-Based Technology for Treatment of Obesity
Date:1/11/2012

ted oral capsules containing UGP281 demonstrated a sustained weight reduction of >8% compared to placebo for a period of 5 weeks. In comparative studies at comparable concentrations, UGP281 demonstrates greater reductions in body weight than other peptide drugs currently in development. Based on the results to date in animal models, UGP281 was well tolerated and offers the potential of a patient friendly orally dosed peptide therapy for the management of obesity.

Unigene expects to file an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) and commence a Phase 1 study with UGP281 before year end.

About Unigene Laboratories, Inc.
Unigene Laboratories, Inc. is a leader in the design, delivery, manufacture and development of peptide-based therapeutics. The Company is building a robust portfolio of proprietary partnerships in this expanding drug class based on its Peptelligence™ platform. Peptelligence encompasses extensive intellectual property covering delivery and manufacturing technologies, unsurpassed research and development expertise, and proprietary know-how representing a genuine distinctive competence. Core Peptelligence assets include proprietary oral and nasal peptide delivery technologies, and proprietary, high-yield, scalable and reproducible E. coli-based manufacturing technologies.

Safe Harbor statements under the Private Securities Litigation Reform Act of 1995: This press release contains forward-looking statements, including statements relating to whether: the Company will achieve the highlighted multiple near-term catalysts and unlock significant value over the next 12 months; the key elements are in place to address the Company's debt in 2012; there will be significant growth in the Company in 2012; the Company will continue to deliver results; the Company's near-term milestones will allow it to extend its cash runway, address the debt and continue to unlock the Com
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SOURCE Unigene Laboratories, Inc.
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