Navigation Links
UbiVac Opens Trial of Next Generation Lung Cancer Vaccine
Date:11/5/2013

SYDNEY, Nov. 5, 2013 /PRNewswire/ -- UbiVac, a clinical stage cancer immunotherapy company based in Portland, OR, announced the results of a Phase I clinical trial and the initiation of a Phase II clinical trial of its first-in-class autophagosome DRibble vaccine, DPV-001, in two presentations at the 15th World Conference for Lung Cancer, in Sydney, from October 27-30. The multicenter, randomized Phase II clinical trial of DPV-001 is supported by a US$3.4 million National Cancer Institute (NCI) grant and will involve 48 individuals with definitively treated stage IIIA/B non-small cell lung cancer (NSCLC). A description of DPV-001, an "off-the-shelf vaccine," was presented by Dr. Helen Ross, Mayo Clinic Arizona, in an oral session (abstract #O-08.01). This next generation vaccine contains a system for targeting to dendritic cells, at least 9 cancer antigens prioritized by an NCI advisory panel and 5 toll-like receptor agonists to boost immunity. "Patients with locally advanced lung cancer still have a very high risk of cancer returning despite our most aggressive treatments," said Dr. Rachel Sanborn, the trial's principal investigator and the Co-Director of Thoracic Oncology, Providence Cancer Center, Portland, Oregon. "This novel vaccine approach may help the immune system recognize and fight remaining cancer cells." In a presentation of the Phase 1 trial in patients with Stage IV NSCLC, the authors reported that immune responses were detected in a majority of the evaluable patients (abstract # P-3.11-032).

"UbiVac is excited to pioneer this first-in-class vaccine technology to patients with NSCLC," said Dr. Hong-Ming Hu, inventor of autophagosome DRibble technology, Co-founder and CSO of UbiVac. "In addition to lung cancer, UbiVac is actively pursuing the application of this technology, with our partners and collaborators, for the treatment of head and neck, hepatocellular, prostate, colon and breast cancer."

UbiVac, spun-out from the Providence Health System in 2005, recently was judged by Oregon CEOs as the top "Presenting Company" at the Oregon Bioscience Association annual meeting has three vaccine platform technologies under development: DRibbles, a nanotechnology platform and a disabled cytomegalovirus (CMV) vector platform.

The ongoing activities reported in this release are supported by the NCI of the National Institutes of Health under Award Numbers R44CA121612 and U43CA165048. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NCI or the National Institutes of Health.


'/>"/>
SOURCE UbiVac
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Biotest Opens New Plasma Center in Melbourne, Florida
2. Industry Landscape Opens Doors for GeoBargain Polydex Pharmaceuticals
3. AdvaMed 2013: The MedTech Conference Opens Monday in Washington, D.C.
4. Unique Glaucoma Test Through Eyelid DIATON Opens Doctors Eyes to Possibility of In-Office Glaucoma Test at Pri-Med East and American Academy of Family Physicians, AAFP
5. Dr. George O. Gavrila Opens Baltimore Tattoo Removal, Offers Astanza Duality Laser Technology
6. Boston Scientific Opens Institute For Advancing Science, Innovation Center In Shanghai
7. BioReliance Opens New U.S. Clearance Services Laboratories; Completes Global Facility Upgrade Plan
8. MinuteClinic Opens Its First Walk-in Medical Clinic in Southwest Virginia
9. Orange County Physician Owned Medical Group Opens Pioneering Medical Facility
10. Life Technologies Opens State-of-the-Art DNA Forensics Laboratory in India
11. MinuteClinic Opens Its First Medical Clinics in Lehigh Valley
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/12/2017)... , Sept. 12, 2017  Consumer reviews on the independent ... as the number one company for hearing aids, ranking it ... fifteen other brands. ... Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high performance, ...
(Date:9/9/2017)... 9, 2017  Eli Lilly and Company (NYSE: ... endpoint data for lasmiditan, an investigational, oral, first-in-class molecule ... significant improvements compared to placebo in the Phase 3 ... the 18th Congress of the International Headache Society (IHC) ... data presented today demonstrate lasmiditan,s potential to reduce pain ...
(Date:9/7/2017)... NuvoAir (formerly called Pond Healthcare Innovation), the company commercializing ... Pharma AG to distribute NuvoAir,s spirometry technology to physicians worldwide. ... platform and Novartis, commitment to address the unmet medical needs ... ... "We are ...
Breaking Medicine Technology:
(Date:9/20/2017)... ... September 20, 2017 , ... FirstAlign ( http://www.firstalign.com ), ... latest Artificial Intelligence (AI) thinking, announced today the launch of its revamped web ... essential information that offers a more comprehensive understanding of the organization’s business and ...
(Date:9/20/2017)... ... September 20, 2017 , ... On Thursday, the Triangle ... Work in the Research Triangle for 2017. , Winners were chosen based on ... meet a threshold in employee participation--a percentage that varies based upon the size ...
(Date:9/20/2017)... ... September 20, 2017 , ... Doctors on Liens has added ... network of medical professionals working on a personal injury lien basis. Founded by Dr. ... brings these esteemed doctors’ vast experience with orthopedic injuries to patients in the Inland ...
(Date:9/20/2017)... ... 2017 , ... Mirror Mirror Beauty Boutique is excited to ... Autumn with CoolSculpting®. Scheduled for Thursday, September 28th, the afternoon will include live ... Boutique is Houston’s largest CoolSculpting provider, holding the prestigious title of ...
(Date:9/20/2017)... ... September 20, 2017 , ... Announced that ... clinical and commercial support services market) has entered into an agreement on September ... , The PGSD is the first private Dental School to launch an ...
Breaking Medicine News(10 mins):